How are pans and PANDAS diagnosed?

To diagnose PANDAS or PANS, doctors will take time talking to you and asking questions about your child's symptoms. They will do an exam and test for infections. Treatment starts with medicine to take care of the infection. Treatment also includes cognitive behavioral therapy for OCD.
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How do you test for pans and PANDAS?

To test for the possibility of PANDAS/PANS, your family doctor will likely first complete a physical examination, starting with a test for strep via throat swab or possibly blood test for antibodies. In some cases, depending on the test results, your doctor may continue searching for other bacterial infections.
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How is pans disease diagnosed?

There are no tests to definitively diagnose PANS or PANDAS. But, the Cunningham Panel™ is the first and only test available that can assist physicians in making a diagnosis.
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What are the signs of PANDAS?

PANDAS Symptoms Checklist
  • Sudden onset of OCD-like symptoms.
  • Irritability or aggression.
  • Depression or extreme moodiness.
  • Poor motor coordination.
  • Tics or unusual movements.
  • Sensitivity to light, sound or touch.
  • Visual hallucinations.
  • Sleep disturbances or fatigue.
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Does PANDAS show up in blood work?

PANDAS/PANS is a clinical diagnosis based on a collection of signs, symptoms, medical history and laboratory findings that cannot be explained by another medical condition. There is no conclusive blood test for PANDAS/PANS, which can make it challenging to get a diagnosis for your child.
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A Childhood Mystery: PANDAS and PANS Disorder



How do I know if my child has pans?

To diagnose PANDAS or PANS, doctors will take time talking to you and asking questions about your child's symptoms. They will do an exam and test for infections. Treatment starts with medicine to take care of the infection. Treatment also includes cognitive behavioral therapy for OCD.
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How do I know if my child has PANDAS?

PANDAS is short for Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections. A child may be diagnosed with PANDAS when: Obsessive-compulsive disorder (OCD), tic disorder, or both suddenly appear following a streptococcal (strep) infection, such as strep throat or scarlet fever.
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What happens if PANDAS go untreated?

Symptoms of PANDAS can leave your child unable to function at school or in social situations. Untreated, symptoms of PANDAS may continue to worsen and can result in permanent cognitive damage. For some children, PANDAS can become a chronic autoimmune condition.
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How do I check my PANS?

What should I do if I think my child has PANS or PANDAS?
  1. It is advised that the pediatrician test the child for both a rapid strep throat, and if negative, by culture.
  2. A peri-anal rapid strep test would be recommended if the patient is also experiencing rash, pain, redness or itching.
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Is PANS an autoimmune disease?

PANS and PANDAS are infection-induced autoimmune conditions that disrupt a patient's normal neurologic functioning, resulting in a sudden onset of Obsessive Compulsive Disorder (OCD) and/or motor tics.
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Will PANDAS go away without treatment?

According to current research, PANDAS is a pediatric disease caused by a strep infection, which is common in young children and demonstrated in these prevalence rates. PANDAS/PANS symptoms seem to flare and remit throughout childhood and disappear in adulthood with proper treatment and symptom maintenance.
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What kind of doctor treats pans?

Doctors who treat PANDAS syndrome come from a variety of backgrounds. Pediatrics, neurology, hematology/oncology, psychology, psychiatry, integrative medicine, immunology and rheumatology are just a few of the specialties of PANDAS doctors.
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What causes pans flare ups?

PANS can be triggered by viruses, bacteria, mold, allergies, and even emotional trauma and stress!
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What is the best antibiotic to treat PANDAS?

Azithromycin and penicillin have been utilized in the treatment of PANDAS with observations of improvement in neuropsychiatric symptoms.
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Can children outgrow pans?

In fact, some studies suggest that about 95% of kids will outgrow PANS or PANDAS by adolescence or young adulthood when their immune systems fully mature.
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Can you have mild PANDAS?

Mild: Symptoms are significant and cause disruptions at home and/or school. They occupy a few hours a day. The PANDAS Physicians Network (PPN) flowcharts for diagnosis and treatment will help clinicians evaluate their patients and determine the best course of treatment.
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How long does a pans flare last?

Flares not treated with NSAIDs had a mean duration of approximately 12.2 weeks (95% CI: 9.3–15.1).
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What is the difference between PANS and PANDAS?

PANDAS is the only subtype of PANS that requires that symptoms be associated with a strep infection. PANS has been reported to occur in association with a variety of infectious agents, including influenza, varicella, and mycoplasma pneumoniae.
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Can Benadryl help with PANDAS?

In addition to their immunologic properties, the H1 blockers (such as diphenhydramine or Benadryl) are “soporific” drugs which produce sleepiness; this side effect can be useful for PANDAS children with initial insomnia.
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Can pans cause brain damage?

Not much is known about the condition and many pediatricians aren't aware it exists, according U.S. News & World Report. Some experts say PANS is triggered by an infection, like strep throat, which causes the immune system to attack the brain.
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Are pans brain inflammation?

MRI brain scans show subtle changes consistent with inflammation in a severe childhood disease in which the immune system is thought to attack the brain, Stanford researchers found.
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Why is PANDAS controversial?

Still, PANDAS has attracted a vocal band of proponents who have proposed it as a catchall for a wide range of mental health issues sometimes lumped under the broader term 'autoimmune encephalopathy. ' The list of purported triggers has grown from strep to include Lyme disease, mononucleosis and herpes.
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Can PANDAS last into adulthood?

CAN TEENAGERS AND ADULTS GET PANS & PANDAS? The short answer is yes. While the focus in research has been on children with PANS, the link between the immune system and neuropsychiatric symptoms can be seen in patients of many ages.
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Is PANDAS Recognised by the NHS?

The NHS doesn't currently recognise PANDAS, even though the disease is recognised by the WHO and has an ICD10 code. Our GP had been saying that tics are very common at a young age and our son will grow out of it.
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Are autism and PANDAS related?

What is the relationship between PANDAS and autism? So far as we can tell, PANDAS does not occur more often in children with autism than among other children. However, PANDAS may be more difficult to recognize in a child with autism – due to overlapping symptoms.
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