What is the sweet syndrome?

Sweet syndrome (acute febrile neutrophilic dermatosis
dermatosis
A skin condition, also known as cutaneous condition, is any medical condition that affects the integumentary system—the organ system that encloses the body and includes skin, nails, and related muscle and glands.
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) is a neutrophilic dermatosis characterized by the abrupt appearance of edematous and erythematous papules, plaques, or nodules on the skin. Fever, leukocytosis, and internal organ involvement can also occur.
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What causes Sweet syndrome?

In most cases, the cause of Sweet's syndrome isn't known. The condition is sometimes associated with blood cancers, such as leukemia, or solid tumors, such as breast or colon cancer. It might also occur as a reaction to a medication — most commonly a type of drug that boosts production of white blood cells.
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Why is it called sweets syndrome?

Acute febrile neutrophilic dermatosis also has the eponymous name, Sweet syndrome or disease—named after Dr Robert Douglas Sweet from Plymouth, England, who first described it in 1964.
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Is Sweet syndrome serious?

These symptoms can point to a number of health conditions, including one you may never have heard of: Sweet syndrome. Usually, this rare skin condition (also known as acute febrile neutrophilic dermatosis) isn't serious and clears up without treatment.
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How is Sweet syndrome diagnosed?

Your doctor diagnoses Sweet syndrome by performing a thorough physical examination. Doctors may perform a skin biopsy if they can't make a diagnosis after a physical exam. For a biopsy, your doctor takes a skin tissue sample and sends it to a laboratory for further evaluation.
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Sweet’s disease, explained by a dermatopathologist. Unk #16.



Is Sweet syndrome autoimmune?

Key Messages. Sweet syndrome is a rare skin condition characterised by fever and sudden onset of painful skin lesions. In rare cases, Sweet syndrome has been reported to occur in association with Sjögren's syndrome, an autoimmune condition characterised by dry eyes and mouth.
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Can Sweet syndrome cause death?

The recurrence of Sweet syndrome may coincide with or precede a hematological relapse. No transformation into acute myeloid leukemia occurred in our cases. However, 7 of the 9 patients died in a follow-up period of 3 to 9 years, confirming the poor prognosis of Sweet syndrome associated with myelodysplasia.
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What does Sweets disease look like?

The major symptom of Sweet syndrome is the sudden onset of tender or painful bumps (nodules or papules) on the arms, legs, face or neck. They may also occur on the thighs and trunk. Papules are solid, raises lesions; nodules are slightly larger and may extend deeper into the skin.
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Is Sweet syndrome itchy?

The cutaneous manifestations of Sweet's syndrome include tender, non-itchy, red-to-purple papules and plaques that can enlarge as the disease progresses. Sometimes these lesions enlarge and may coalesce to cover large areas of the body.
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Is Sweet's syndrome contagious?

Sweet's syndrome (also known as acute febrile neutrophilic dermatosis) is a rare skin disorder characterised by a fever and the appearance of tender red or purple lumps or patches on the skin that may ulcerate. It is not contagious, not hereditary and not a form of skin cancer.
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Is there a cure for Sweet's syndrome?

Sweet's syndrome might go away without treatment. But medications can speed the process. The most common medications used for this condition are corticosteroids: Pills.
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Who discovered Sweet syndrome?

Dr Robert Douglas Sweet first described and used the term acute febrile neutrophilic dermatosis, back in 1964 based on his observations in 8 women. However, the name “Sweet's syndrome” is established as the eponym for acute febrile neutrophilic dermatosis and used worldwide.
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What does a lesion look like?

Skin lesions are areas of skin that look different from the surrounding area. They are often bumps or patches, and many issues can cause them. The American Society for Dermatologic Surgery describe a skin lesion as an abnormal lump, bump, ulcer, sore, or colored area of the skin.
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What causes dermatosis?

Conditions of the skin, also known as dermatoses, can be caused by a variety of factors, including infections, irritation, autoimmune diseases, or cancer. Treatment for dermatosis depends on the cause, and may include topical steroids, moisturizers, antibiotics, antifungals, or chemotherapy.
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What is pyoderma Gangrenosum?

Pyoderma gangrenosum (pie-o-DUR-muh gang-ruh-NO-sum) is a rare condition that causes large, painful sores (ulcers) to develop on your skin, most often on your legs.
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What is lupus vulgaris?

Lupus vulgaris is the most common form of cutaneous tuberculosis that occurs in previously sensitized individuals with a moderate degree of immunity against tubercle bacilli. The different types of lupus vulgaris include plaque, ulcerative, vegetative, papular and nodular, and tumor forms.
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What is febrile neutrophilic dermatosis?

Acute febrile neutrophilic dermatosis is a skin condition characterized by fever, inflammation of the joints (arthritis), and painful skin lesions that appear mainly on the face, neck, back and arms.
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Does lupus cause Sweet syndrome?

Interestingly, Sweet syndrome was the initial manifestation of lupus in 33% of their patients. The pathogenesis of Sweet syndrome in SLE is unclear but is likely the result of immunologic abnormalities in SLE causing cytokine stimulation resulting in neutrophil chemotaxis.
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Is chronic cellulitis an autoimmune disease?

The exact cause of familial eosinophilic cellulitis is still not known. Some scientists believe that there may be an autoimmune basis for the disorder.
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Is cellulitis caused by autoimmune disease?

Weak Immune System

An autoimmune disease — such as lupus or rheumatoid arthritis — can also weaken the immune system. This not only makes you vulnerable to cellulitis, but also to other infections, such colds and the flu.
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Why is my whole body itches at night?

Circadian rhythm

In the evening, the body releases more heat, and blood flow to the skin increases, which may contribute to nighttime itching. In addition, skin loses water at night, resulting in dryness that can make you itchy.
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What does it mean when your itchy all over?

Itching on the whole body might be a symptom of an underlying illness, such as liver disease, kidney disease, anemia, diabetes, thyroid problems, multiple myeloma or lymphoma. Nerve disorders. Examples include multiple sclerosis, pinched nerves and shingles (herpes zoster). Psychiatric conditions.
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What do little red dots in skin mean?

Petechiae are tiny spots of bleeding under the skin. They can be caused by a simple injury, straining or more serious conditions. If you have pinpoint-sized red dots under your skin that spread quickly, or petechiae plus other symptoms, seek medical attention.
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Which infection is called sweetie?

Sweet syndrome or neutrophilic dermatosis is a rare inflammatory disorder where the patient develops acute onset of lesions (sores or blisters) on the skin (neutrophilic lesions) associated with fever, joint pains, and headache.
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What is tens skin condition?

Toxic epidermolysis necrosis on a woman's back

TEN causes large areas of blistering, peeling skin. Toxic epidermal necrolysis (TEN) is a rare, life-threatening skin reaction, usually caused by a medication. It's a severe form of Stevens-Johnson syndrome (SJS).
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