What happens if you take antidepressants for too long?

Those who had used antidepressants for >3 years reported more severe side effects, including “weight gain”, “addiction”, “feeling not like myself ”, “withdrawal symptoms”, and “suicidality”, than those who had been on antidepressants for ≤2 years.
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How long is too long to be on antidepressants?

Clinicians generally recommend staying on the medication for six to nine months before considering going off antidepressants. If you've had three or more recurrences of depression, make that at least two years.
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What are the side effects of long-term use of antidepressants?

Long-Term Effects of Antidepressants
  • Sexual problems (72%), including the inability to reach orgasm (65%)
  • Weight gain (65%)
  • Feeling emotionally numb (65%)
  • Not feeling like themselves (54%)
  • Reduced positive feelings (46%)
  • Feeling as if they're addicted (43%)
  • Caring less about other people (36%)
  • Feeling suicidal (36%)
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Can you stay on antidepressants for life?

For people with chronic or severe depression, medication may be needed on a long-term basis. In these cases, antidepressants are often taken indefinitely. That is, in part, because depression is not an illness that can be cured.
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Is it OK to take antidepressants long-term?

Guidance from the National Institute of Health and Care Excellence recommends that antidepressants are used as 'maintenance' treatment for up to 2 years to prevent their depression returning (relapse). It also recommends cognitive-behavioural therapy to change habits of thought and behaviour.
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How Long Should You Use Antidepressants?



Do antidepressants permanently affect brain?

Some research has suggested this type of drug aids in neuroplasticity. In other words, these drugs can affect how our minds organize and form synaptic connections. Other researchers believe this type of medication has no long-term effects on our brains once the individual stops using the drug.
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How long is the average person on antidepressants?

The length of treatment varies.

Even once you do start to feel better, you should expect to remain on your antidepressant for at least 4 to 6 additional months. Those experiencing depression for the first time may require even longer, from 6 to 12 months.
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Does your brain go back to normal after antidepressants?

If the symptoms develop later or gradually, they may constitute a relapse of the depression. Ultimately, these withdrawal symptoms will improve with time, but they can be unpleasant for days and possibly even weeks. In time, the brain readjusts and people should experience a return to their normal state.
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Is it impossible to get off antidepressants?

Antidepressant withdrawal is possible if you abruptly stop taking an antidepressant, particularly if you've been taking it longer than four to six weeks. Symptoms of antidepressant withdrawal are sometimes called antidepressant discontinuation syndrome and typically last for a few weeks.
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Why should you not just stop taking antidepressants?

It's important that you do not stop taking antidepressants suddenly. A dose of antidepressants should be slowly reduced, normally over 4 weeks, but sometimes longer. This is to prevent any withdrawal symptoms you might get as a reaction to coming off antidepressants suddenly.
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How do you know when to go off antidepressants?

Stopping antidepressants suddenly is not dangerous but you could get withdrawal symptoms or become unwell again if you make a sudden change. If you can, stop your antidepressant when you have felt better for the last six months on medication. Plan in advance to cut down your dose gradually.
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Can antidepressants stop working after 20 years?

If you feel like your antidepressant has stopped working, you're not alone. It's common for a medication that once worked wonders to become ineffective, especially if you've been taking it for a long time. Symptoms return for up to 33% of people using antidepressants — it's called breakthrough depression.
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Is there an alternative to antidepressants?

Exercise. Research suggests that regular exercise may be a more effective treatment for mild depression than antidepressants. Exercise helps boost levels of chemicals called serotonin and dopamine in the brain, which can lift your mood.
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How long should you stay on antidepressants for anxiety?

It's usually recommended that a course of antidepressants continues for at least 6 months after you feel better, to prevent your condition recurring when you stop. Some people with recurrent illness are advised to carry on taking medicine indefinitely.
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What do antidepressants do to your head?

Antidepressants work by boosting the activity of particular brain chemicals, or making the activity last longer. This includes noradrenaline and serotonin, which are thought to be involved in regulating your mood. Noradrenaline and serotonin are neurotransmitters.
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Should antidepressants be permanent?

Antidepressants can either be prescribed as a short-term treatment for those with acute symptoms, or long-term for those who may experienced worsened symptoms. Many people who are known to have histories of recurrent depressive episodes may even require indefinite treatment with antidepressants.
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Can antidepressants cause more harm than good?

Our review supports the conclusion that antidepressants generally do more harm than good by disrupting a number of adaptive processes regulated by serotonin. However, there may be specific conditions for which their use is warranted (e.g., cancer, recovery from stroke).
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Can long-term antidepressants cause memory loss?

Tranquilizers, antidepressants, some blood pressure drugs, and other medications can affect memory, usually by causing sedation or confusion. That can make it difficult to pay close attention to new things. Talk to your doctor or pharmacist if you suspect that a new medication is taking the edge off your memory.
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What vitamin is a natural antidepressant?

Vitamin B-3 and Vitamin B-9 can help people with depression because B vitamins help the brain manage moods. Vitamin D, melatonin and St. John's Wort are recommended for seasonal depression. Omega-3 fatty acids, magnesium and vitamin C may also help with depression.
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What is a natural anti antidepressant?

Natural antidepressants include SAM-e, St John's Wort, and omega-3-fatty acids, among others. If a person thinks they have symptoms of depression, they should speak to a doctor before trying any natural antidepressants.
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What works better than antidepressants?

Exercise

At 10 months, exercise was more effective than antidepressant medication. To get the antidepressant benefits of exercise, walk like you're late for 45 minutes 4-5 times a week. In addition, do weight training twice a week as it can increase testosterone, which improves mood, memory, and motivation.
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How long after stopping antidepressants will I feel better?

The return of depression or anxiety usually takes longer – typically weeks or months. Some antidepressants, like fluoxetine, take a lot longer to leave the body. So, with these, symptoms can start days or even weeks after stopping or reducing your dose.
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Is it OK to stop antidepressants cold turkey?

People taking antidepressants should never stop “cold turkey.” Quitting suddenly throws the brain into a state of imbalance that can be worse than before. The resulting symptoms are both psychological and physical.
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