What are Zoladex injections?

Goserelin is a type of hormone therapy. It is also known as Zoladex. This page is about goserelin for breast cancer in women who haven't gone through the menopause. Goserelin is also a treatment for prostate cancer and is sometimes used to treat men with breast cancer.
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Is Zoladex a form of chemotherapy?

Zoladex - Chemotherapy Drugs - Chemocare.
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What does Zoladex do to the body?

It works by decreasing testosterone hormones in men and estrogen hormones in women. This effect helps to slow or stop the growth of certain cancer cells and uterine tissue that need these hormones to grow and spread.
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Is Zoladex cancer treatment?

Goserelin is a type of hormone therapy. It is also known as Zoladex. You might have it as a treatment for breast or prostate cancer.
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What kind of treatment is Zoladex?

Zoladex contains the drug goserelin, which belongs to a class of medications called gonadotropin releasing hormone (GnRH) agonists. (A medication class is a group of drugs that work in a similar way.) Zoladex is a type of hormone therapy that works to lower levels of sex hormones such as testosterone and estrogen.
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Zoladex injections - How to give and what to expect



How long can you be on Zoladex for?

It is important that you carry on receiving your Zoladex 10.8 even if feeling well unless your doctor decides it is time for the treatment to stop. Women should only receive Zoladex 10.8 for a maximum of 6 months. If you miss a treatment: You should not delay or miss your 12 or 13 weekly Zoladex 10.8.
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What happens after first Zoladex injection?

After goserelin has been given, you may notice an area of redness or bruising at the injection site, but this should disappear within a few hours. Occasionally, bruising may be there for a few days. Some women notice a change in their breast size.
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Is Zoladex better than tamoxifen?

Compared to women who didn't get either medicine, the risk of breast cancer coming back was 33% lower for women who got 2 years of Zoladex and 29% lower for women who got 2 years of tamoxifen.
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Are Zoladex injections painful?

You usually have injections under the skin (subcutaneous injection) into the stomach. You might have stinging or a dull ache for a short time after this type of injection but they don't usually hurt much. The skin in the area may go red and itchy for a while.
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Where do you inject Zoladex?

ZOLADEX, at a dose of 3.6 mg, should be administered subcutaneously every 28 days into the anterior abdominal wall below the navel line using an aseptic technique under the supervision of a physician [see Administration Technique].
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How do you feel after Zoladex?

After your first Zoladex implant, it takes 2 to 4 weeks for your hormone levels to drop. Many of Zoladex's side effects, such as hot flashes, acne, and sexual problems, are related to this hormone level drop. As a result, you may notice most of Zoladex's side effects starting within 2 to 4 weeks.
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Does Zoladex put you into menopause?

Rapid onset of menopausal symptoms. If menopausal symptoms are to occur they may occur more rapidly after oophorectomy, whereas the use of Zoladex tends to induce a more gentle menopause.
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When should Zoladex be given?

You should be given a Zoladex LA injection every 12 weeks. Always remind the doctor or nurse to set up an appointment for your next injection. If you are given an appointment for your next injection which is earlier or later than 12 weeks from your last injection, tell your doctor or nurse.
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What does Zoladex do to ovaries?

Zoladex blocks a hormone produced in the brain called GnRH that triggers the ovaries to make estrogen. Blocking the ovaries from making estrogen is called ovarian suppression. It can slow the growth of HR+ breast cancer or help prevent it from coming back.
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Does Zoladex cause joint pain?

This medication can be associated with joint or muscle aches and pains. If it is bothersome, it may be treated with medications.
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Can you drink alcohol on Zoladex?

What drugs and food should I avoid while taking Zoladex (Goserelin (Implant))? Avoid drinking alcohol. It can increase your risk of bone loss while you are being treated with goserelin.
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Can I inject Zoladex myself?

Zoladex® 3.6mg is only available with a doctor's prescription and can only be administered by a nurse or doctor.
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Does Zoladex cause tiredness?

Tell your doctor right away if you have any serious side effects, including: vaginal burning/pain (in women), pain during sex (in women), breast pain/tenderness, new/worsening bone pain, new broken bone, burning feeling in feet/toes, swelling of the ankles/feet, unusual tiredness, change in the amount of urine, stomach ...
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Do you still have periods on Zoladex?

Zoladex 3.6 will usually stop your periods. Some women will have a menstrual period in the first 2 weeks after the first injection of Zoladex 3.6. Rarely, some women may enter their natural menopause when being treated with Zoladex 3.6 and will not resume having periods when the treatment with Zoladex 3.6 stops.
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What happens after stopping Zoladex?

Hot flushes and sweating. Occasionally these side effects may continue for some time (possibly months) after stopping Zoladex. A reduced sex drive. Pain, bruising, bleeding, redness or swelling where Zoladex is injected.
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Can I have my ovaries removed instead of taking tamoxifen?

If you have a high likelihood of developing estrogen-receptor-positive breast cancer but you don't want to take hormonal therapy, prophylactic ovary removal could be an option. You have had breast cancer and do not want to take medications that temporarily suppress estrogen production by the ovaries.
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What does ovarian suppression mean?

Treatment that stops or lowers the amount of estrogen made by the ovaries. Types of ovarian suppression include surgery to remove both ovaries, radiation therapy, and the use of certain drugs. Ovarian suppression may be used to prevent and treat breast cancer. Also called ovarian ablation.
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What does Zoladex do to fibroids?

Two hundred and forty-seven patients with uterine fibroids were randomized to surgery alone or 3 months' Zoladex® (Zeneca, Macclesfield, Ches., UK) followed by surgery. Zoladex significantly reduced uterine and fibroid volumes (p = 0.0001).
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Can you drive after Zoladex injection?

Zoladex is not likely to affect you being able to drive or use any tools or machines. weeks (28 days). This will be done by your doctor or nurse. It is important that you keep having Zoladex treatment, even if you are feeling well.
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How much does Zoladex cost?

The cost for Zoladex subcutaneous implant 3.6 mg is around $835 for a supply of 1 implant, depending on the pharmacy you visit. Prices are for cash paying customers only and are not valid with insurance plans. Zoladex is available as a brand name drug only, a generic version is not yet available.
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