What are long term side effects of antidepressants?

Long-Term Effects of Antidepressants
  • Sexual problems (72%), including the inability to reach orgasm (65%)
  • Weight gain (65%)
  • Feeling emotionally numb (65%)
  • Not feeling like themselves (54%)
  • Reduced positive feelings (46%)
  • Feeling as if they're addicted (43%)
  • Caring less about other people (36%)
  • Feeling suicidal (36%)
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What are the long-term effects of taking antidepressants?

Two recent reviews of research in this area concluded that discontinuation effects, sexual dysfunction, weight gain, and sleep disturbance (multiple long-wake periods) are adverse effects of long-term SSRI use.
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Do antidepressants affect your brain long-term?

Some research has suggested this type of drug aids in neuroplasticity. In other words, these drugs can affect how our minds organize and form synaptic connections. Other researchers believe this type of medication has no long-term effects on our brains once the individual stops using the drug.
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How long is too long to be on antidepressants?

It's usually recommended that a course of antidepressants continues for at least 6 months after you feel better, to prevent your condition recurring when you stop. Some people with recurrent illness are advised to carry on taking medicine indefinitely.
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Does your brain go back to normal after antidepressants?

If the symptoms develop later or gradually, they may constitute a relapse of the depression. Ultimately, these withdrawal symptoms will improve with time, but they can be unpleasant for days and possibly even weeks. In time, the brain readjusts and people should experience a return to their normal state.
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The 'extreme' side-effects of antidepressants - BBC News



Do antidepressants cause dementia?

Certain antidepressants and bladder medications are linked to increased risk of dementia, according to new University of East Anglia research funded by Alzheimer's Society and published today in the British Medical Journal.
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Do antidepressants change your personality?

Fact: When taken correctly, antidepressants will not change your personality. They will help you feel like yourself again and return to your previous level of functioning.
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Do antidepressants shorten your life?

The analysis found that in the general population, those taking antidepressants had a 33 percent higher risk of dying prematurely than people who were not taking the drugs. Additionally, antidepressant users were 14 percent more likely to have an adverse cardiovascular event, such as a stroke or a heart attack.
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Is it OK to take antidepressants for life?

MYTH: Once on antidepressants, I'll be on them for life. FACT: Not true. A general rule clinicians often use is that a person should be treated with antidepressants at least one-and-a-half times as long as the duration of the depressive episode before they can begin to be weaned off.
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Is it okay to be on antidepressants for years?

Long-term—even indefinite—use of antidepressants may be the best treatment for someone with multiple past episodes of depression, especially if they have a history of suicide attempts or have residual symptoms, like sleep problems, says Dr. Potash.
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What are the benefits of coming off antidepressants?

Besides easing the transition, tapering the dose decreases the risk that depression will recur. In a Harvard Medical School study, nearly 400 patients (two-thirds of them women) were followed for more than a year after they stopped taking antidepressants prescribed for mood and anxiety disorders.
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How do you know when to go off antidepressants?

Your doctor might recommend stopping your antidepressant if: You're feeling better, and you and the doctor agree that it's time to stop. You have been taking the medicine for at least 6 months.
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Do antidepressants affect intelligence?

Serretti et al. showed that using SSRIs even in healthy individuals leads to cognitive impairment [25]. The memory loss caused by SSRIs has not yet been convincingly explained; however, serotonin appears to play an important role in learning and memory [26].
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Do antidepressants heal the brain?

Scientists have long known that SSRIs rapidly increase the available amount of the neurotransmitter serotonin, leading to changes that go well beyond brain chemistry: Research suggests the drugs help reverse the neurological damage associated with depression by boosting the brain's innate ability to repair and remodel ...
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Are antidepressants harmful?

Antidepressants can cause dizziness and unsteadiness, increasing the risk of falls and bone fractures, especially in older people. Interactions with other medications can increase this risk. A very small number of people have had heart problems, epileptic fits or liver damage while taking antidepressants.
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What does antidepressants do to the brain?

SSRIs treat depression by increasing levels of serotonin in the brain. Serotonin is one of the chemical messengers (neurotransmitters) that carry signals between brain nerve cells (neurons). SSRIs block the reabsorption (reuptake) of serotonin into neurons.
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How can I get off antidepressants naturally?

Never stop "cold turkey." In many cases, the best way to stop taking most antidepressants is to slowly cut back your dose under the guidance of your doctor. This is called tapering. Tapering helps your brain adjust to the chemical changes and can help prevent discontinuation symptoms.
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Does brain fog from antidepressants go away?

These symptoms of brain fog may be short-term or ongoing as you take these medications. While antidepressants are generally intended to help with brain fog, some can cause brain fog as a side effect, depending on the medication and your unique response to it.
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Can SSRIs cause permanent brain damage?

Long-term use of antidepressants could cause permanent damage, doctors warn. NHS figures show antidepressant prescriptions in England doubled in the last decade, with more than 70 million handed out in 2018.
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Do antidepressants Make You Age Faster?

Surprising results among those taking antidepressants

Researchers believe this may be due to the tendency for antidepressants to relax the facial muscles, leading to more drooping than would otherwise be the case for a particular patient's chronological age.
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How do you know if your antidepressant is too high?

Signs and symptoms include:
  1. Agitation or restlessness.
  2. Insomnia.
  3. Confusion.
  4. Rapid heart rate.
  5. Dilated pupils.
  6. Loss of muscle coordination or twitching muscles.
  7. High blood pressure.
  8. Muscle rigidity.
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Can antidepressants make you mean or angry?

SSRIs are the first line of therapy for anxiety and depressive disorders and for many other clinical diagnoses. One of the most disturbing side effects that is observed is a tendency towards aggressiveness among patients receiving medications from this group, mainly during the first month of therapy.
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Do antidepressants take away your emotions?

Antidepressants and dulled emotions

Doctors typically treat MDD with antidepressants like selective serotonin reuptake inhibitors (SSRIs) or serotonin-norepinephrine reuptake inhibitors (SNRIs). A 2017 survey reported that 46% of people on antidepressants experienced symptoms of emotional numbness.
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Do antidepressants help with self esteem?

In addition to treating depression, they seemed to make certain people more assertive or less curmudgeonly than they had ever been before. Soon more of my patients said the medication made them feel more confident.
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Are antidepressants a good idea?

Research suggests that antidepressants can be helpful for people with moderate or severe depression. They're not usually recommended for mild depression, unless other treatments like talking therapy have not helped.
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