What antidepressant works with tramadol?

Dual action antidepressants mirtazapine (Remeron), duloxetine (Cymbalta), and most notably venlafaxine (Effexor), which tramadol is closely related to in structure, also inhibit NE and 5HT reuptake.
Takedown request   |   View complete answer on pubmed.ncbi.nlm.nih.gov


Which antidepressant Can you take with tramadol?

Tramadol as a factor.

With regard to the antidepressant interactions, SS has been reported with combinations of tramadol and the following: fluoxetine,2628 sertraline,2931 paroxetine,3235 citalopram,36 fluvoxamine,37 venlafaxine,38,39 and TCAs.
Takedown request   |   View complete answer on ncbi.nlm.nih.gov


Which classes of antidepressants should be avoided in patients who are taking tramadol?

Tramadol is also commonly implicated in new onset seizures with therapeutic use. This risk is further heightened when it is co-administered with SSRIs, tricyclic antidepressants, venlafaxine and bupropion.
Takedown request   |   View complete answer on nps.org.au


Can you take tramadol with SSRIs?

The combination of tramadol and SSRIs or SNRIs can result in the serotonin syndrome, which is potentially dangerous but easily avoidable if prescribers are aware of this risk.
Takedown request   |   View complete answer on ncbi.nlm.nih.gov


Can I take Prozac and tramadol together?

They work by increasing the level of serotonin in the brain, according to Mayo Clinic. “If tramadol is taken together with fluoxetine (Prozac), sertraline (Zoloft), or any of the SSRI medications, the combination can increase the risk of a serious condition called serotonin syndrome.
Takedown request   |   View complete answer on webmd.com


Tramadol



Can I take tramadol while on antidepressants?

Tramadol can be safely combined with antidepressants; however, monitoring and counseling patients are prudent when starting a new serotonergic agent or when doses are increased.
Takedown request   |   View complete answer on pubmed.ncbi.nlm.nih.gov


Can you take Lexapro and tramadol?

Because tramadol increases serotonin production in the brain, taking it along with drugs like Zoloft and Lexapro, common antidepressants, can result in a potentially life-threatening situation.
Takedown request   |   View complete answer on sunrisehouse.com


Can I take Wellbutrin with tramadol?

buPROPion traMADol

TraMADol may rarely cause seizures, and combining it with other medications that can also cause seizures such as buPROPion may increase that risk.
Takedown request   |   View complete answer on drugs.com


Can you take sertraline with tramadol?

by Drugs.com

It's best to avoid taking tramadol with sertraline as there is potential for a severe interaction. Please see link below for interaction in detail. Talk with your doctor or pharmacist about other safer pain relief options.
Takedown request   |   View complete answer on drugs.com


Can I take tramadol and Paxil?

PARoxetine traMADol

Severe cases may result in coma and even death. You should contact your doctor immediately if you experience these symptoms while taking the medications. Using traMADol with PARoxetine may also increase the risk of seizures not related to the serotonin syndrome.
Takedown request   |   View complete answer on drugs.com


Can I take amitriptyline and tramadol together?

amitriptyline traMADol

TraMADol may rarely cause seizures, and combining it with other medications that can also cause seizures such as amitriptyline may increase that risk.
Takedown request   |   View complete answer on drugs.com


What medications should not be taken with tramadol?

You should not take other medicines that also contain tramadol. This includes Conzip®, Qdolo, Rybix™, Ryzolt™, Ultram®, Ultram® ER, or Ultracet®. Using these medicines together may increase your chance for more serious side effects.
Takedown request   |   View complete answer on mayoclinic.org


Does tramadol affect serotonin levels?

Tramadol increases the concentration of serotonin in the synapses between the serotonergic neurons found in the brain stem. This extra serotonin causes some of the positive effects of the medication, such as pain relief.
Takedown request   |   View complete answer on serenityatsummit.com


Can tramadol cause anxiety and depression?

Respiratory depression is a serious side effect that may occur in people taking tramadol. If a person has difficulty breathing while taking tramadol, they must seek emergency medical attention. People can experience respiratory depression with usual dosages of tramadol.
Takedown request   |   View complete answer on medicalnewstoday.com


Is it OK to take mirtazapine with tramadol?

traMADol mirtazapine

Severe cases may result in coma and even death. You should contact your doctor immediately if you experience these symptoms while taking the medications. Using traMADol with mirtazapine may also increase the risk of seizures not related to the serotonin syndrome.
Takedown request   |   View complete answer on drugs.com


Can you take duloxetine and tramadol together?

Because of it is analgesic properties, duloxetine in the lower antidepressant doses (60 mg taken ones daily) combined with tramadol (another analgesic agent) can be useful in CPS for patients who do not respond satisfactory to monotherapy.
Takedown request   |   View complete answer on sciencedirect.com


Which is stronger tramadol or amitriptyline?

Tramadol is more effective than morphine and amitriptyline against ischaemic pain but not thermal pain in rats. Pharmacol Res.
Takedown request   |   View complete answer on pubmed.ncbi.nlm.nih.gov


Can you take painkillers with antidepressants?

Taking antidepressants together with painkillers can substantially increase the risk of bleeding from the stomach, according to new research by the University of East Anglia.
Takedown request   |   View complete answer on medicalxpress.com


Can I take tramadol with Seroquel?

Using traMADol together with QUEtiapine can lead to serious side effects including seizures, respiratory distress, coma, and even death. Combined use can also increase the risk of an irregular heart rhythm that may be serious and potentially life-threatening, although it is a relatively rare side effect.
Takedown request   |   View complete answer on drugs.com


Can traMADol and Buspar be taken together?

busPIRone traMADol

Using narcotic pain or cough medications together with other medications that also cause central nervous system depression can lead to serious side effects including respiratory distress, coma, and even death.
Takedown request   |   View complete answer on drugs.com


Can you take Zyban and traMADol together?

Let your healthcare professionals (e.g. doctor or pharmacist) know that you are taking these medicines together.Do not take more than the prescribed dose of tramadol. Your healthcare professionals may already be aware of this interaction and may be monitoring you for it.
Takedown request   |   View complete answer on webmd.com


Can you take traMADol and lorazepam?

Can You Take Ativan With Tramadol? You should not take Ativan (lorazepam) with tramadol, especially if you're taking either without a prescription, which is also dangerous. Because both drugs are central nervous system depressants, combining the two can amplify their side effects.
Takedown request   |   View complete answer on banyantreatmentcenter.com


Is tramadol used to treat anxiety?

Tramadol reduces anxiety-related and depression-associated behaviors presumably induced by pain in the chronic constriction injury model of neuropathic pain in rats.
Takedown request   |   View complete answer on pubmed.ncbi.nlm.nih.gov


Can you take clonazePAM with tramadol?

clonazePAM traMADol

Using narcotic pain or cough medications together with other medications that also cause central nervous system depression can lead to serious side effects including respiratory distress, coma, and even death. Talk to your doctor if you have any questions or concerns.
Takedown request   |   View complete answer on drugs.com


What painkillers can I take with Zoloft?

Safer Pain Relief Options with Zoloft

For over-the-counter pain relief without the risk of thinning the blood, acetaminophen (Tylenol) is a safer choice because it does not have the same side effects.
Takedown request   |   View complete answer on wellrx.com
Previous question
What is Swiss death cleaning?