Is a freckle on the eye serious?

A freckle in your eye might seem odd, but they're actually common and usually harmless. If you have one, your eye doctor may want to watch it over time. It's rare, but they can turn into a type of cancer called melanoma.
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What percentage of eye freckles are cancerous?

It is a flat pigmented lesion that is benign, with roughly one in 10 people developing this type of nevus. Although it is generally noncancerous, a choroidal nevus still has a small potential to become cancerous. That is why it needs to be followed by your eye doctor.
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How do I know if my eye freckles are cancerous?

When to See Your Eye Doctor About That Eye Freckle
  1. You notice your eye freckle has grown or changed its shape or color.
  2. You have eye pain.
  3. You see flashing lights.
  4. You notice other changes in your vision.
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What does a freckle on the eyeball mean?

An eye freckle is called a nevus (“nevi” is the plural), and different kinds of freckles can occur on different parts of the eye. While usually harmless, they do need to be monitored by a doctor because there's a small chance they can become a type of cancer called melanoma.
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Can a freckle in the eye be removed?

Can a nevus be removed? Because nevi don't affect your vision or cause health problems, they usually don't need to be removed. In fact, removal could do more damage than good. However, if a nevus becomes cancerous, your ophthalmologist may recommend it be removed with radiation therapy or surgery.
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What causes eye freckles? Are they dangerous?



How common is melanoma in the eye?

Ocular melanoma is the most common primary cancer affecting the eye. However, it is a rare disorder and is estimated to be diagnosed in about 2,500 people in the United States each year. The incidence is unknown, but one estimate places it at about 5-6 people per every 1,000,000 people in the general population.
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Is eye melanoma curable?

These rare cancers can be treated with either surgical removal of the tumor, if it is small enough, or radiation therapy. In more advanced cases or if there is serious eye damage, enucleation (removal of the eyeball) may be needed.
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Should I be worried about freckles?

In most cases, freckles are harmless. They form as a result of overproduction of melanin, which is responsible for skin and hair color (pigmentation). Overall, freckles come from ultraviolet (UV) radiation stimulation. There are two categories of freckles: ephelides and solar lentigines.
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What causes freckles on the retina?

An eye freckle is very similar to a mole on your skin or a freckle. And similar to both moles and freckles, a nevus can be brown, yellow or gray. Cells called melanocytes produce melanin, which gives color to your skin and to your eyes, and when these cells lump together, an eye freckle is the result.
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Can a freckle be melanoma?

Some freckles can look normal but can potentially be a melanoma freckle. Most melanomas usually share a few tell-tale warning signs.
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Is ocular melanoma a death sentence?

Choroidal melanoma is a disease with a high mortality rate, usually irrespective of the chosen treatment modality. About 30-50% of patients with choroidal melanoma will die within 10 years from diagnosis and treatment. Death is usually secondary to distant metastases, and the risk is greatest in larger tumors.
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Is melanoma of the eye life threatening?

Called "OM" for short, ocular melanoma is a malignant tumor that can grow and spread to other parts of the body - this process, known as metastasis, is often fatal and occurs in about half of all cases.
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What does iris melanoma look like?

Circumscribed iris melanomas appear as a variably pigmented well-defined mass in the iris stroma and is more commonly found in the inferior half of the iris. The degree of pigmentation can vary as well as the shape. Some are small and flat and others are elevated and dome shaped.
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Can a nevus appear suddenly?

Moles, or nevi, typically form during childhood and adolescence, but new moles can appear in adulthood. Although most moles are noncancerous, or benign, the development of a new mole or sudden changes to existing moles in an adult can be a sign of melanoma.
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What does a nevus look like?

A common mole (nevus) is a small growth on the skin that is usually pink, tan, or brown and has a distinct edge. A dysplastic nevus is often large and does not have a round or oval shape or a distinct edge. It may have a mixture of pink, tan, or brown shades.
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How can you tell the difference between a melanoma and a choroidal nevus?

Choroidal nevi are slate-gray and relatively flat (less than 2mm thickness), although there is significant size overlap between small melanomas and larger nevi. Like choroidalal melanomas (i.e. full-blown eye cancers), they also may show overlying drusen or lipofuscin (figure 2).
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What does a spot on your retina mean?

A Roth spot, also known as a Litten spot, is a hemorrhage — the release of blood from a ruptured blood vessel — in the retina. The retina is the part of the eye that senses light and sends visual information to your brain, allowing you to see. ‌ Roth spots are only visible during an eye exam.
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When should a freckle be checked?

A mole or freckle should be checked if it has a diameter of more than a pencil eraser or any characteristics of the ABCDEs of melanoma (see below). Dysplastic nevi are moles that are generally larger than average (larger than a pencil eraser) and irregular in shape.
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What does Stage 1 melanoma look like?

Stage IA Melanoma: The melanoma tumor is less than 1.0 millimeter thick (less than the size of a sharpened pencil point) with or without ulceration (broken skin) when viewed under the microscope. Stage IB Melanoma: The melanoma tumor is more than 1.0 millimeter and less than 2.0 millimeters thick without ulceration.
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What does Stage 1 melanoma mean?

Stage I Melanoma

This is a noninvasive stage, which is also called melanoma “in situ,” meaning “in its original place.” With stage I melanoma, the tumor's thickness is 1mm or less. This tumor may or may not have ulcerated, and it isn't yet believed to have spread beyond the original site.
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What are the symptoms of melanoma in the eye?

When they do occur, signs and symptoms of eye melanoma can include:
  • A sensation of flashes or specks of dust in your vision (floaters)
  • A growing dark spot on the iris.
  • A change in the shape of the dark circle (pupil) at the center of your eye.
  • Poor or blurry vision in one eye.
  • Loss of peripheral vision.
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What is the survival rate for melanoma of the eye?

The 5-year survival rate for eye melanoma is 82%. When melanoma does not spread outside the eye, the 5-year relative survival rate is about 85%. The 5-year survival rate for those with disease that has spread to surrounding tissues or organs and/or the regional lymph nodes is 71%.
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How long does it take for ocular melanoma to metastasize?

Approximately 50% of ocular melanoma patients will develop metastatic disease within 15 years of the original diagnosis, and currently there is no cure for metastatic OM.
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What is the treatment for melanoma behind the eye?

Surgery is the most common treatment for intraocular melanoma. The following types of surgery may be used: Resection: Surgery to remove the tumor and a small amount of healthy tissue around it. Enucleation: Surgery to remove the eye and part of the optic nerve.
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