Does omeprazole hurt your bones?

The present study corroborates the previous findings, given that a relationship between omeprazole use and decreased bone mineral density was demonstrated. This can be taken to be a predictive sign indicating that fractures may occur as a result of long-term PPI use.
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Do proton pump inhibitors weaken bones?

Long-term PPI therapy is reported to be associated with decreased bone mineral density (BMD) [14,15,16]. Reduction in BMD and deterioration of bone microstructure are characteristics of osteoporosis, a metabolic bone disease [17].
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Can PPI cause bone pain?

Proton pump inhibitors (PPIs) do not appear to be associated with changes in bone strength or bone structure, according to a new report. 1. Targownik LE, Goertzen AL, Luo Y, et al. Long-term proton pump inhibitor use is not associated with changes in bone strength and structure.
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Can omeprazole cause fractures?

May 25, 2010 -- Popular PPI antacids -- Aciphex, Dexilant, Nexium, Prevacid, Prilosec, Protonix, Vimovo, and Zegerid -- raise the risk of bone fracture, especially when used for a year or more or at high doses, the FDA warns.
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Does omeprazole cause calcium deficiency?

In a study of elderly women, administration of omeprazole decreased the absorption of calcium, presumably because the drug decreased the stomach's production of hydrochloric acid, which is necessary for calcium absorption. The form of calcium used in the study to test calcium absorption was calcium carbonate.
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Omeprazole side effects: Long term use- Surprising facts



What happens if you take omeprazole for too long?

Prilosec (omeprazole) is a proton pump inhibitor that treats severe stomach acid-related conditions like GERD. Common Prilosec side effects include headache, stomach pain and nausea. Long-term Prilosec use has been linked to kidney damage, bone fractures and other dangerous side effects.
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Does omeprazole cause hip pain?

Stop using omeprazole and call your doctor at once if you have: severe stomach pain, diarrhea that is watery or bloody; new or unusual pain in your wrist, thigh, hip, or back; seizure (convulsions);
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What are the two medications that may cause osteoporosis after long-term use?

High doses or long-term use of medicines called proton pump inhibitors (PPIs) can raise the risk of bone loss. PPIs, such as esomeprazole, lansoprazole, and omeprazole, are used for GERD (acid reflux), peptic ulcer, or heartburn. However, getting enough calcium and vitamin D may be enough to lower the risk.
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Do proton pump inhibitors make osteoporosis worse?

In September 2012, the US Food and Drug Administration issued a warning regarding use of proton pump inhibitors (PPIs) and osteoporosis stating that “several published observational studies suggest that proton pump inhibitor (PPI) therapy may be associated with an increased risk for osteoporosis-related fractures of ...
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What drugs make your bones ache?

Medications that can cause joint and muscle pain
  • Antibiotic: levofloxacin. ...
  • Osteoporosis medication: bisphosphonates. ...
  • Asthma inhalers. ...
  • Breast cancer medications: anastrozole, exemestane, letrozole. ...
  • Acne treatment: isotretinoin. ...
  • Nerve pain / anti-seizure medication: pregabalin. ...
  • Estrogen medication: Premarin.
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What medications can weaken your bones?

  • High doses of corticosteroids.
  • High doses of thyroid medicines.
  • Medicines that reduce levels of sex hormones.
  • Certain diabetes medicines.
  • Certain stomach medicines, such as proton pump inhibitors or antacids containing aluminum.
  • Certain antidepressants.
  • Mood stabilizers containing lithium.
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What medications cause bones to hurt?

Hormone Drugs
  • Anastrozole (Arimidex)
  • Exemestane (Aromasin)
  • Leuprolide (Lupron Depot)
  • Goserelin (Zoladex)
  • Medroxyprogesterone acetate (Depo-Provera)
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Can acid reflux affect your bones?

Changing the acidity of your digestive system affects your body's ability to absorb bone-boosting calcium. Long-term use of PPIs may also cause vitamin B-12 deficiency. This damages your nerves and increases your risk for falls.
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Can acid reflux cause osteoporosis?

Gastroesophageal reflux disease (GERD) with proton pump inhibitor (PPI) use is associated with an increased risk of osteoporosis.
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Can omeprazole cause osteopenia?

Conclusion: Short-term administration of omeprazole has no significant influence on bone density and does not increase the incidence of osteopenia and osteoporosis.
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What does osteoporosis pain feel like?

Sudden, severe back pain that gets worse when you are standing or walking with some relief when you lie down. Trouble twisting or bending your body, and pain when you do. Loss of height.
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How do you increase your bone density?

Keep reading for tips on increasing bone density naturally.
  1. Weightlifting and strength training. ...
  2. Eating more vegetables. ...
  3. Consuming calcium throughout the day. ...
  4. Eating foods rich in vitamins D and K. ...
  5. Maintaining a healthy weight. ...
  6. Avoiding a low calorie diet. ...
  7. Eating more protein. ...
  8. Eating foods rich in omega-3 fatty acids.
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Is walking good for osteoporosis?

You can prevent bone loss with regular exercise, such as walking. If you have osteoporosis or fragile bones, regular brisk walking can help to keep your bones strong and reduce the risk of a fracture in the future. How should you walk and how often? You should walk briskly on a regular basis.
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Can omeprazole cause nerve pain?

Symptoms can include: nervousness. neuritis (inflammation of a nerve) numbness or tingling in your hands and feet.
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What are the most common side effects of omeprazole?

Common side effects of omeprazole include:
  • headache.
  • abdominal pain.
  • diarrhea.
  • nausea.
  • vomiting.
  • gas (flatulence)
  • dizziness.
  • upper respiratory infection.
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What is an alternative to omeprazole?

These include proton pump inhibitors such as esomeprazole (Nexium), omeprazole (Prilosec), pantoprazole (Protonix) and lansoprazole (Prevacid). The others are antacids such as Maalox, Mylanta and Tums; and H2 (histamine) receptor antagonists such as famotidine (Pepcid), and cimetidine (Tagamet).
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Is it OK to take omeprazole every day?

You should not take it for more than 14 days or repeat a 14-day course more often than every 4 months unless directed by a doctor. Do not crush, break, or chew the tablet. This decreases how well Prilosec OTC works in the body.
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What is the longest you should take omeprazole?

How long to take it for. If you bought the medicine yourself from a pharmacy or supermarket, you can take it for up to 14 days. If you feel no better after taking omeprazole for 14 days, tell your doctor. They may want to do tests to find out what's causing your symptoms or change you to a different medicine.
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Is it OK to take omeprazole every other day?

Conclusion: Alternate-day, long-term treatment with omeprazole may be adequate to maintain remission in patients with reflux esophagitis. This regimen can assure serum gastrin levels within the normal range, thus reducing the potential risk of prolonged, sustained hypergastrinemia and profound hypochlorhydria.
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Do antacids cause bone loss?

Indiscriminate use of over-the-counter antacids may be weakening your bones. Acidity and reflux is a bane of our stressful times. Most do not think twice before popping an antacid to check heartburn, but doctors warn that regular consumption of the drug can weaken your bones and cause osteoporosis.
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