Can omeprazole cause hip problems?

PPI use (overall) and 5 generic ingredients (omeprazole, esomeprazole, pantoprazole, lansoprazole, rabeprazole) were reported to be associated with fractures. Long-term or cumulative PPI use did not increase hip fracture risk, but risk of hip fracture was modestly increased during current short-term PPI use.
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Can PPI cause hip pain?

The discomfort for patients with reflux (aka GERD) drives them to seek help. Proton pump inhibitors (PPI) come to the rescue for many Minster reflux sufferers. Unfortunately, these PPIs may trigger pain elsewhere, especially the hip for which the risk of fracture is increased, even though they help with GERD.
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Can omeprazole hurt your bones?

The present study corroborates the previous findings, given that a relationship between omeprazole use and decreased bone mineral density was demonstrated. This can be taken to be a predictive sign indicating that fractures may occur as a result of long-term PPI use.
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Can PPIs cause joint pain?

Background: Proton pump inhibitors (PPIs) have a significant impact on the gut microbiome, which in turn, might increase the risk of rheumatoid arthritis (RA).
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Does Prilosec cause hip pain?

Stop using omeprazole and call your doctor at once if you have: severe stomach pain, diarrhea that is watery or bloody; new or unusual pain in your wrist, thigh, hip, or back; seizure (convulsions);
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Causes of Hip Pain - Everything You Need To Know - Dr. Nabil Ebraheim



Can omeprazole cause joint inflammation?

Serious side effects

you get joint pain along with a red skin rash, especially on parts of your body exposed to the sun, such as your arms, cheeks and nose – these can be signs of a rare condition called subacute cutaneous lupus erythematosus. This can happen even if you have been taking omeprazole for a long time.
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Can acid reflux cause joint and muscle pain?

Heartburn is often due to gastroesophageal reflux disease, or GERD. This may not be related to joint pain and muscle cramps, which could be present at the same time due to other conditions.
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Can omeprazole cause nerve pain?

Symptoms can include: nervousness. neuritis (inflammation of a nerve) numbness or tingling in your hands and feet.
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What are the most common side effects of omeprazole?

Common side effects of omeprazole include:
  • headache.
  • abdominal pain.
  • diarrhea.
  • nausea.
  • vomiting.
  • gas (flatulence)
  • dizziness.
  • upper respiratory infection.
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Can acid reflux make your whole body hurt?

Heartburn is often a symptom of reflux disease, and body aches or pains along with fatigue can occur following exercise or physical activity. Body aches can also accompany infections. Dizziness can be present with many illnesses, particularly if dehydration occurs.
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Can omeprazole cause osteopenia?

Conclusion: Short-term administration of omeprazole has no significant influence on bone density and does not increase the incidence of osteopenia and osteoporosis.
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Can PPI cause bone loss?

In September 2012, the US Food and Drug Administration issued a warning regarding use of proton pump inhibitors (PPIs) and osteoporosis stating that “several published observational studies suggest that proton pump inhibitor (PPI) therapy may be associated with an increased risk for osteoporosis-related fractures of ...
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Can acid reflux affect your bones?

Changing the acidity of your digestive system affects your body's ability to absorb bone-boosting calcium. Long-term use of PPIs may also cause vitamin B-12 deficiency. This damages your nerves and increases your risk for falls.
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What are the two medications that may cause osteoporosis after long-term use?

High doses or long-term use of medicines called proton pump inhibitors (PPIs) can raise the risk of bone loss. PPIs, such as esomeprazole, lansoprazole, and omeprazole, are used for GERD (acid reflux), peptic ulcer, or heartburn. However, getting enough calcium and vitamin D may be enough to lower the risk.
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Does Pantoprazole cause hip pain?

Pantoprazole may increase your risk of having fractures of the hip, wrist, and spine. This is more likely if you are 50 years of age and older, if you receive high doses of this medicine, or use it for one year or more. Call your doctor right away if you have severe bone pain or are unable to walk or sit normally.
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Does Nexium weaken bones?

Nexium, manufactured by AstraZeneca, and Prevacid, made by Takeda, are associated with a significantly increased risk of hip, wrist and vertebral spine fractures and cause bones to deteriorate and break.
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What happens when you stop taking omeprazole?

When omeprazole is stopped, a common side effect is rebound acid secretion, where the acid secretion in your stomach increases significantly. This should return to normal within 2 weeks.
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How long can you safely take omeprazole?

You should not take it for more than 14 days or repeat a 14-day course more often than every 4 months unless directed by a doctor. Do not crush, break, or chew the tablet.
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What is considered long-term use of omeprazole?

In a clinical context, use of PPI for more than 8 weeks could be a reasonable definition of long-term use in patients with reflux symptoms and more than 4 weeks in patients with dyspepsia or peptic ulcer.
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Can omeprazole cause restless legs?

In some instances a drug side-effect may be the cause of a patient's restless leg syndrome. Some antidepressants like fluoxetine, diphenhydramine, tricyclic drugs like amitriptyline, lithium, beta blockers, and even several acid reducers like omeprazole can cause symptoms of restless leg syndrome.
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Can long term use of omeprazole cause neuropathy?

A new analysis of the FDA adverse events database (FAERS) has reported that use of proton pump inhibitors (e.g. omeprazole, rabeprazole, lansoprazole, pantoprazole) may be associated with a risk of neurological conditions, including hearing and visual impairment, memory loss, neuropathy and migraine (Sci Rep 2019;9: ...
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Can PPIs cause peripheral neuropathy?

Furthermore, we found significant associations of PPI use with a wide range of neurological adverse reactions including, migraine, several peripheral neuropathies, and visual and auditory neurosensory abnormalities.
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Can acid reflux affect your legs?

Venous reflux, also known as venous insufficiency, can lead to: Leg swelling. Pain. Telangiectasias (fine spider veins)
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What is lupus joint pain like?

Lupus can also cause inflammation in the joints, which doctors call “inflammatory arthritis.” It can make your joints hurt and feel stiff, tender, warm, and swollen. Lupus arthritis most often affects joints that are farther from the middle of your body, like your fingers, wrists, elbows, knees, ankles, and toes.
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Can omeprazole cause leg pain?

muscle pain, weakness, and infrequently, leg cramps and water retention.
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