Why was bupropion taken off the market?

Initially approved in December 1985, Wellbutrin was withdrawn from the market by Burroughs Wellcome in March 1986 because of an unacceptable rate of seizures in a small study of nondepressed bulimic patients.
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Is bupropion recalled?

The medication being recalled is sold under the generic name of bupropion hydrochloride extended-release. The recall only applies to the 150mg tablets that were produced in the company's manufacturing facility in Halol, India. Although a recall has been issued, the recalled drug is not likely to cause injury.
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Why is there a bupropion shortage?

Shortage of generic manufacturers

All five bupropion manufacturers with declared shortages have said an increase in demand was the cause of at least one shortage, and they're struggling to keep up.
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Is generic bupropion as good as Wellbutrin?

The FDA considers the generic form of bupropion XL 300 mg (Teva Pharmaceuticals) bioequivalent and therapeutically equivalent to (interchangeable with) Wellbutrin XL 300 mg.
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What are the dangers of bupropion?

What Are The Possible Side Effects Of Bupropion? Headache, weight loss, dry mouth, trouble sleeping (insomnia), nausea, dizziness, constipation, fast heartbeat, and sore throat. These will often improve over the first week or two as you continue to take the medication.
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How and When to use Bupropion? (Wellbutrin, Zyban) - Medical Doctor Explains



Is bupropion a strong antidepressant?

Bupropion is an effective antidepressant with efficacy comparable to selective serotonin reuptake inhibitors and other antidepressants. It is well tolerated in short-and longer-term treatment.
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Can bupropion cause memory loss?

Tell your doctor right away if you have any serious side effects, including: fast/pounding/irregular heartbeat, mental/mood changes (such as anxiety, agitation, confusion, unusual behavior/thinking, memory loss), unusual weight loss or gain.
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What drug can replace Wellbutrin?

The Food and Drug Administration (FDA) approved these atypical antidepressants to treat depression:
  • Bupropion (Wellbutrin SR, Wellbutrin XL, others)
  • Mirtazapine (Remeron)
  • Nefazodone.
  • Trazodone.
  • Vilazodone (Viibryd)
  • Vortioxetine (Trintellix)
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What's the difference between bupropion and bupropion?

USP officially designates the SR formulation as“ bupropion hydrochloride; tablet, extended release.” The generic name for the XL formulation is “bupropion hydrochloride; tablet, extended release.” Although the generic drug names are the same, the two products are not therapeutically equivalent or interchangeable.
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Is Wellbutrin different from bupropion?

Wellbutrin, or bupropion, is a drug that is mainly used to treat depression. It can also be used to help people stop smoking. Other names include Aplenzin, and Forfivo XL. This article will look at how Wellbutrin is used, how it works, its side effects, and any important warnings.
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Is Wellbutrin discontinued?

FDA announced certain generic Wellbutrin to be pulled off of the shelves. The 300 mg generic version of Wellbutrin XL made by Impax Laboratories and marketed by Teva Pharmaceuticals is being recalled.
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What drug is currently in shortage 2021?

The most recent drug added to the FDA's shortage list was heparin sodium and sodium chloride 0.9 percent injection, an anticoagulant, on Jan. 7. Dexmedetomidine injection, a sedative used for patients on ventilators, was added Dec. 27, 2021.
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What happens when you stop taking Wellbutrin?

Common withdrawal symptoms of Wellbutrin include irritability, dizziness, headaches, aggression, flu symptoms, anxiety, depression, sleep changes, nausea, cramps, tremors, suicidal thoughts, excessive sweating, trouble balancing and difficulty tolerating warm temperatures.
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Does bupropion cause weight gain?

Though most antidepressants can cause weight gain, bupropion is a medication for depression that can lead to weight loss. If people with depression are concerned about weight gain, this might be a suitable option. People who do not have depression should not take bupropion to lose weight.
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Can bupropion cause tinnitus?

Tinnitus caused by bupropion is most likely due to dopaminergic enhancement. Tinnitus perception is processed in the prefrontal, primary temporal, and temporoparietal associative areas, as well as in the limbic system that overlaps cerebral dopaminergic projections.
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What pharmaceutical company makes bupropion?

[10-3-2012] The U.S. Food and Drug Administration (FDA) has reviewed new data that indicate Budeprion XL 300 mg (bupropion hydrochloride extended-release tablets), manufactured by Impax Laboratories, Inc., and marketed by Teva Pharmaceuticals USA, Inc., is not therapeutically equivalent to Wellbutrin XL 300 mg.
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Does Wellbutrin give you energy like Adderall?

With the increase of dopamine that Wellbutrin provides, some patients may experience a boost of energy and motivation while taking Wellbutrin.
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Does bupropion give you energy?

Conclusions: Our results demonstrated that bupropion increased some enzymes of brain energy metabolism. These findings are in accordance with other studies which showed that some antidepressants may improve energy metabolism.
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Is bupropion good for anxiety?

Also known as bupropion, Wellbutrin has been established as an effective antidepressant demonstrating an impressive ability to reduce anxiety levels. There are many benefits to Wellbutrin as an anxiety treatment, including its lack of common mood medication symptoms, like weight gain and sexual side effects.
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Which is better Lexapro or Wellbutrin?

Wellbutrin vs Lexapro: Which is better? There is no clear-cut answer in choosing between Lexapro and Wellbutrin. That is because each person is different, with potentially different responses and sensitivities to a medication. Both drugs have been effective in depressed patients.
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Who should not take Wellbutrin?

You should not take Wellbutrin if you are allergic to bupropion, or if you have: a seizure disorder; an eating disorder such as anorexia or bulimia; or. if you have suddenly stopped using alcohol, seizure medications, or a sedative (such as Xanax, Valium, Fiorinal, Klonopin, and others).
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Is Wellbutrin better than Zoloft?

Is Wellbutrin or Zoloft better? Multiple studies have shown Wellbutrin and Zoloft to be relatively comparable in achieving remission of depression symptoms. Wellbutrin may be favored over Zoloft due to the fact that its side effect profile is less severe.
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What are the 9 Common drugs Linked to Alzheimer's?

Caution! These 10 Drugs Can Cause Memory Loss
  • Antianxiety drugs (Benzodiazepines) ...
  • Cholesterol-lowering drugs (Statins) ...
  • Antiseizure drugs. ...
  • Antidepressant drugs (Tricyclic antidepressants) ...
  • Narcotic painkillers. ...
  • Parkinson's drugs (Dopamine agonists) ...
  • Hypertension drugs (Beta-blockers)
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What does bupropion do to the brain?

This medication works by improving your mood and your sense of well-being. This is achieved by restoring the chemical balance of dopamine and norepinephrine in the brain. Bupropion is also used off-label for the treatment of a variety of health conditions such as: Attention Deficit Hyperactivity Disorder (ADHD)
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Does your brain go back to normal after antidepressants?

"The fact that antidepressant withdrawal can be so prolonged suggests that the drug has changed the brain and that those changes are taking a very long time to return to normal and it may be the case that sometimes they don't go back to normal."
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