Why is rheology important in pharmaceutical industry give examples?

Drug Formulation and Process Development

Rheological characterization tools, such as viscometers, allow drug producers to directly affect how a drug is formulated and developed, cutting across parameters and conditions to arrive at product characteristics that can be quantified.

What are the examples of rheology?

Many physiological materials and fluids exhibit complicated rheology. Within the eye, examples include the vitreous humour, the liquid in the tear film, and the blood in capillaries.

What are the pharmaceutical applications of rheology?

Examples of pharmaceutical applications of rheology can be exemplified by the following: Surfactants, poly(oxyethylene)-poly(oxypropylene)-poly(oxyethylene) block copolymers, also known as Pluronic® and poloxamers, exhibit Newtonian behavior in the liquid state, at low concentrations and low temperatures.

What is the importance of rheology?

Researchers believe that rheological characterization is essential for the development, optimization, and processing of foods. Food rheology also determines the food texture. Rheological flow properties deal with the perception of food when we touch or put it into our mouth.

What is rheology and its application?

Rheology is science which treats the deformation and flow of materials. The science of rheology is applied to the physics, chemistry, engineering, medicine, dentistry, pharmacy, biology and so on. Classical theory of elasticity treats the elastic solid which is accordant to Hooke's law [ 1].

Rheology Essentials for Pharmaceutical Scientists Part 1

Why is rheology important in cosmetics?

Rheological measurements provide information about storage stability, processability or flow properties of liquid and semi-solid formulations, which are essential for quality control and further product development.

What is medical rheology?

[re-ol´ah-je] the science of the deformation and flow of matter, such as the flow of blood through the heart and blood vessels.

Why is the rheological property important to understand polymers?

Understanding the rheological properties of polymers through laboratory testing can help to optimize products and process conditions, thereby saving costs and minimizing potential waste.

Why is rheological measurement important in food quality control?

Investigating food using rheological tests

Rheological tests are useful to: Investigate the fluid and structural properties of raw materials used in food production. Improve the texture, taste, and mouthfeel of food. Predict the materials' performance during processing.

What is rheology in food processing?

Food rheology is the study of the consistency and flow of food under specified applied forces, to understand the underlying physicochemical principles of 'structuring' by food materials and their interaction.

Why is viscosity important in pharmaceutical industry?

Viscosity is a key indicator of quality in a wide range of biotech applications, from pharmaceuticals and mechanical devices to medical laboratories and research centers. Viscosity measurement is important when it comes to determining a wide range of data points—such as at what point can a fluid flow through a syringe?

What are the pharmaceutical applications of thixotropy?

The time-dependent change in viscous nature of thixotropy finds its major applications in pharmaceutical formulations including hydrogel, ointment, suspensions and emulsions through various routes including oral, topical, ophthalmic and mucosal administration, as shown in Table 2.

What is Rheogram in physical pharmacy?

Pharmaceutics, Pharmacy Notes. Rheology is the science which deals with flow of the liquid and deformation of the solid. The term 'rheology' was derived from the Greek words rheo (flow) and logos (science).

What are rheological properties of fluids?

Rheological properties refer to the Bingham plastic fluid parameters such as yield point (YP) and plastic viscosity (PV). It is one of the several flow characteristics of drilling fluid, workover fluid or completion fluid or cement.

What is rheology modifiers in cosmetics?

Rheology modifiers are often referred to as thickeners, and whilst increasing the apparent viscosity will confer a feeling of “quality” to the formulation, this is only one aspect of rheological control. The product itself can be Newtonian or pseudoplastic, thixotropic, be a ringing gel or a stringy flowable liquid.

What is rheology testing?

Rheology testing is measuring the deformation of matter under the influence of imposed stress, by analysing the internal response of materials to forces.

How do you determine the rheological properties of liquid foods?

The rheological behavior of fl uid foods is determined by measurements of shear stress versus shear rate/time or elastic/viscous modulus versus frequency, and representation of the experimental data by viscometric/ oscillatory diagrams and empirical equations, as a function of temperature and/or concentration.

What is rheology PDF?

Rheology is the study of the flow of matter, primarily in the liquid state, but also as 'soft solids' or solids under flow conditions in which they respond with plastic flow rather than deforming elastically in response to the applied force.

What are the rheological properties of polymers?

Macroscopic and Microscopic characteristics of Polymers: MW, MWD, time, molecular structure and composition, orientation, solvent, pressure, filler, temperature, and morphology. - Like rubbers, some materials have large recoverable deformation, but the stress is not proportional to the deformation.

What does rheology depend on?

Rheology is the scientific field that encompasses the flow phenomena of matter (solids, liquids, and gases) and notably involves time-dependent behavior under the influence of stresses.

What is rheology measurement?

Measurement. Rheometers are instruments used to characterize the rheological properties of materials, typically fluids that are melts or solution. These instruments impose a specific stress field or deformation to the fluid, and monitor the resultant deformation or stress.

What is the difference between rheology and viscosity?

Viscosity is a quantitative measurement that is useful in chemistry. These two terms are related to fluids such as liquids and gases. The key difference between rheology and viscosity is that rheology is the study of the flow of matter whereas viscosity is a measure of its resistance to deformation.

What is rheology Slideshare?

DEFINITION OF RHEOLOGY  Rheology is the science/physics that concerns with the flow of liquids and the deformation of solids.  Study of flow properties of liquids is important for pharmacist working in the manufacture of several dosage forms, viz., simple liquids, gels, ointments, creams, and pastes.

Is viscosity a rheological property?

The property of rheology is viscosity, which is defined as the measure of the resistance of a fluid to gradual deformation by shear or tension.

Is lotion Pseudoplastic fluid?

According to the ana - lysis of a down-curve at lower shear rates (0–600 s-1) it was con- firmed that samples of body lotions are pseudoplastic sub- stances and the pow- er law model, t = Kg·p, was used (regression coefficients higher than 0.98) to deter- mine consistency parameter, K, and flow index, p.