Why do you gain weight on sertraline?

Antidepressants may cause weight gain by interfering with serotonin or histamine neurotransmitters in the brain that control appetite. Some antidepressants may cause drowsiness or fatigue that lower levels of activity, leading to weight gain.
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Does everyone gain weight on sertraline?

For some people who take an SSRI such as Prozac (fluoxetine) or Zoloft (sertraline), one of these possible side effects is weight gain. Research suggests that the amount of weight typically gained while on an SSRI is modest.
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Does sertraline cause rapid weight gain?

Antipsychotic drugs, antidepressants , and mood stabilizers are common drugs that have the most potential to increase weight gain. All 12 of the leading antidepressants, including fluoxetine (Prozac), sertraline (Zoloft), and escitalopram (Lexapro), make gaining weight more likely.
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How can I avoid gaining weight on antidepressants?

As simple as it may sound, the best chance of avoiding, or lessening further, undesirable weight gain when taking a prescribed antidepressant or antipsychotic medication, is to simultaneously participate in a formal weight management program.
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Can you lose weight while on sertraline?

Sertraline can make you feel more or less hungry than usual, so you may gain or lose weight when you start taking it. If you start to have problems with your weight while taking sertraline, talk to your doctor or pharmacist.
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Does Zoloft cause weight gain? | FNP Explains | Chat and Chill



How do I stop gaining weight on sertraline?

How to Avoid Sertraline Weight Gain
  1. Weigh yourself before you start. ...
  2. Maintain your normal eating habits. ...
  3. Stay active. ...
  4. Weigh yourself weekly, not daily. ...
  5. If you gain weight, tell your healthcare provider. ...
  6. If you lose weight, tell your healthcare provider.
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What should you avoid when taking sertraline?

Do not use sertraline with buspirone (Buspar®), fentanyl (Abstral®, Duragesic®), linezolid (Zyvox®), lithium (Eskalith®, Lithobid®), methylene blue injection, tryptophan, St John's wort, or some pain or migraine medicines (eg, rizatriptan, sumatriptan, tramadol, Frova®, Imitrex®, Maxalt®, Relpax®, Ultram®, Zomig®).
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How much weight do you gain on sertraline?

Official answer. Zoloft (sertraline) may lead to a small weight gain ranging from 1% to 1.6% of initial body weight when used over 6 months to 1 year. For example, in a 150 lb (68 kg) person, this would equal an added 1.5 to 2.4 lbs (0.7 to 1.1 kg) of weight.
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Does sertraline make you hungry?

If you've been prescribed this medication or its generic version, sertraline, you may have experienced an improvement in your mood, sleep, and energy levels. Your appetite might also have increased. Along with these changes, you may begin to notice you have put on a little weight.
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Why do people gain weight on antidepressants?

Antidepressants interfere with serotonin, the neurotransmitter that regulates anxiety and mood while also controlling appetite. In particular, these changes may increase cravings for carbohydrate-rich foods, such as bread, pasta, and desserts.
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How can I lose weight while on antidepressants?

Increasing both aerobic exercise and strength training, ideally four times a week for a minimum of 30 to 45 minutes, can increase muscle tone and metabolism and reduce fat stores. Regular exercise has also been shown to reduce risk for depression relapse when combined with a stable medication regimen.
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How can I lose weight after antidepressants?

How to lose weight after antidepressants
  1. Change medication. Some antidepressants aren't linked to weight gain. ...
  2. Look at your lifestyle. One study on SSRI use and weight gain found that weight gain was more likely in people who also had a Western diet, were sedentary, and smoked⁸. ...
  3. Get active. ...
  4. Get a good night's sleep.
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Is antidepressant weight gain permanent?

The research also raises concerns about the duration of risk that patients are exposed to. Previous studies correlating antidepressants with weight gain have been short-term, typically less than a year.
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Does sertraline cause weight gain NHS?

Sertraline can make you feel more or less hungry than usual, so you may lose or gain weight when you start taking it. If you and your doctor decide to take you off sertraline, your doctor will recommend reducing your dose gradually to help prevent withdrawal side effects.
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Which antidepressants cause the most weight gain?

Tricyclic antidepressants such as amitriptyline and tetracyclic antidepressants such as mirtazapine are linked to the most weight gain.
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Does serotonin cause weight gain?

According to the study published in Natural Medicine, there are 2 types of serotonin. The type that is known for its effects on mood and appetite only accounts for 5% of serotonin in the body, while the other 95%, called peripheral serotonin, plays a role in obesity.
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When is the best time to take sertraline?

When is the best time to take sertraline (Zoloft)? Typically, your doctor will recommend that you take your prescribed dose of sertraline once a day, either in the morning or evening. If sertraline makes you drowsy, your doctor may suggest that you take it at bedtime.
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How do I get rid of weight gain medicine?

Here are some ways to lose weight gained due to medication use:
  1. Switch to a different medication. The first strategy to consider involves changing medications. ...
  2. Lower medication dosage. ...
  3. Limit portion sizes. ...
  4. Exercise. ...
  5. Eat more protein. ...
  6. Talk to a dietitian. ...
  7. Avoid alcohol. ...
  8. Get enough sleep.
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Why can you not drink alcohol with sertraline?

In addition to the common side effects listed above, sertraline can cause excessive sleepiness and reduce your ability to think clearly, react and make decisions. These effects may become more severe when alcohol is consumed while sertraline is active in your body.
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How do you know if sertraline is working?

Sleep, energy, or appetite may show some improvement within the first 1-2 weeks. Improvement in these physical symptoms can be an important early signal that the medication is working. Depressed mood and lack of interest in activities may need up to 6-8 weeks to fully improve.
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What is the best antidepressant for weight loss?

Of these three medications, bupropion (Wellbutrin) is the most consistently associated with weight loss. Several studies, including a 2019 meta-analysis of 27 studies, found that bupropion (Wellbutrin) was the only commonly used antidepressant associated with weight loss.
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Why should you not take sertraline on a night?

Sertraline's effectiveness doesn't depend on the time it's taken, but your sleep schedule may be better if you take it at a certain time of day. For some people, sertraline can make you feel tired and sleepy. For others, sertraline can cause insomnia or difficulty sleeping.
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Is it OK to drink coffee while taking sertraline?

No interactions were found between caffeine and sertraline.
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How long can you stay on sertraline?

For depression it might be six months, for OCD it might be 12 months and for other anxiety related conditions such as PTSD and panic disorder it might be up to 18 months. If you stop taking the sertraline too soon, there is more chance that your symptoms will come back.
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