Why aspirin and clopidogrel are given together?

Aspirin combined with clopidogrel has been shown to decrease the risk of cardiovascular events in patients at higher risk of cardiovascular disease, as well as in those with acute coronary syndrome.

Do I have to take aspirin with clopidogrel?

Do not take aspirin for pain relief (300mg tablets) or ibuprofen while you're taking clopidogrel, unless a doctor has said it's OK. They increase the chance of bleeding. You can take paracetamol together with clopidogrel.

Why is it important that clopidogrel and aspirin are given as soon as an acute myocardial event has happened?

Aspirin combined with clopidogrel can effectively reduce the occurrence of re-thrombosis after PCI and improve the recovery of cardiac function after acute operation, moreover the safety is high.

Why aspirin is given in myocardial infarction?

Aspirin is effective in reducing the blood clots that are blocking a coronary artery during an acute heart attack.

What is the rationale for aspirin and clopidogrel administration during AMI?

The study conducted by Sabatine et al has declared that Clopidogrel and Aspirin combined therapy leads to a significant reduction in the odds of death from cardiovascular causes, recurrent myocardial infarction, and recurrent ischemia of STEMI patients.

Asprin vs Plavix? Which is better?

What's the difference between aspirin and clopidogrel?

What is the difference between aspirin and Plavix (clopidogrel)? Aspirin and Plavix (clopidogrel bisulfate) are drugs used to prevent blood clots. Aspirin and Plavix belong to different drug classes. Plavix is an anticoagulant and aspirin is a nonsteroidal anti-inflammatory drug (NSAID).

Can clopidogrel cause internal bleeding?

Stomach pain is not a common side effect of Plavix. However, if you have stomach pain or cramping while taking this drug, there's a small chance you could have bleeding in your stomach. (Serious bleeding is a possible side effect of Plavix. See “Serious side effects” above.)

Does clopidogrel affect platelet count?

The combination of clopidogrel and IL-6 may account for the smaller decline of platelet count in the patients with more stents. In conclusion, platelet count decreased in the majority of patients with acute coronary syndrome 6 months after stent implantation.

When is the best time to take clopidogrel 75 mg?

You can take clopidogrel at whatever time of day you find easiest to remember, but take your doses at the same time of day each day. Most people prefer to take it in the morning, as they find this helps them to remember to take it regularly. You can take the tablet either before or after a meal.

Does clopidogrel stop clotting?

Clopidogrel is an antiplatelet medicine used to prevent blood clots in patients who have had a heart attack, stroke, or problems with the circulation in the arms and legs. It works by helping to keep the platelets in the blood from sticking together and forming clots that can occur with certain medical conditions.

What is the most serious adverse effect of clopidogrel?

Serious side effects

severe stomach ache or abdominal pain. uncontrolled bleeding or unusual bruising. vomiting with blood. weakness or numbness in an arm or leg.

What are the most common side effects of clopidogrel?

Does clopidogrel affect the kidneys?

Conclusions. In summary, among patients hospitalized with ACS and treated with clopidogrel, lower levels of kidney function were associated with a greater risk of death, hospitalization for AMI, and major bleeding.

Which is safer clopidogrel or aspirin?

Aspirin combined with the antiplatelet drug clopidogrel is no better than aspirin alone for stroke prevention in people with a history of lacunar strokes, and the combination carries a greater risk of gastrointestinal bleeding, according to results of a trial funded by the National Institutes of Health.

Does clopidogrel increase bleeding risk?

In conclusion, we found that among patients receiving DES, clopidogrel use was associated with an increased risk of major bleeding over a broad range of time intervals out to 18 months. In contrast, clopidogrel use was associated with decreased risk of MI in all time intervals and death in the 7- to 12-month interval.

Who needs dual antiplatelet therapy?

Dual antiplatelet therapy is recommended for an ABCD2 score of 4 or greater. Minor stroke can be identified by a National Institutes of Health (NIH) Stroke Scale score of 3 or less. The risk of recurrence after minor stroke is similar to that after a high-risk TIA.

Can atorvastatin be taken with clopidogrel?

Talk to your doctor before using atorvastatin and clopidogrel. This combination may reduce the effects of clopidogrel. Call your doctor promptly if you have any signs of blood clots such as chest pain, shortness of breath, sudden loss of vision, or pain, redness or swelling in an extremity.

Is there an alternative to clopidogrel?

Ticagrelor and prasugrel are antiplatelet drugs that are alternatives to clopidogrel in acute coronary syndrome. Their advantages include reduced rates of ischaemia and stent thrombosis.

Is clopidogrel a blood thinner?

Clopidogrel (Plavix) is a blood thinner that's used to prevent heart attack and stroke in people who are at higher risk for those events.

Does clopidogrel affect blood sugar?

These results could indicate that clopidogrel has glucose lowering effect and the FSG level in placebo treated group significantly elevated after the same course of treatment.

What are the contraindications of clopidogrel?

Why is atorvastatin used?

Atorvastatin is used together with diet, weight loss, and exercise to reduce the risk of heart attack and stroke and to decrease the chance that heart surgery will be needed in people who have heart disease or who are at risk of developing heart disease.

Can you take amlodipine and clopidogrel together?

When used together, they can increase the risk of bleeding complications. Using amlodipine with clopidogrel can raise the risk for heart attack or stroke.

What is aspirin 75mg used for?

Daily low-dose aspirin makes your blood less sticky and helps to prevent heart attacks and stroke. You'll usually take a dose of 75mg once a day.