WHO ORS vs low osmolarity ORS?

However, patients treated with reduced-osmolarity ORS solution had a significantly lower volume of vomiting and significantly higher urine output than those treated with standard WHO-ORS solution. Reduced-osmolarity ORS solution was as efficacious as standard WHO-ORS solution in the management of cholera patients.
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WHO ORS vs low osmolality ORS?

We found that reduced osmolarity ORS has beneficial effects over the WHO standard ORS in reducing needs for unscheduled intravenous fluid infusion, stool output during rehydration, and the number of patients with vomiting during oral rehydration treatment.
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Why is low osmolar ORS better?

It reduces stool output or stool volume by about 25% when compared to the original WHO-UNICEF ORS solution, It reduces vomiting by almost 30%, It reduces the need for unscheduled IV therapy by more than 30%.
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Which type of ORS is best?

Rice based ORS

Tastes better and provide more calories than the glucose based. Culturally acceptable, reduces stool volume (by about 40%) shortens the duration of diarrhea in both cholera and other diarrheal diseases.
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WHO recommended Oral Rehydration Solution?

For more than 25 years, WHO and UNICEF have recommended a single formulation of glucose-based oral rehydration salts to prevent or treat dehydration from diarrhoea irrespective of the cause or age group affected.
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ORS - Oral Rehydration Salt | ReSoMal | Reduced osmolarity ORS, Homemade ORS



What is low osmolarity ORS?

This product, which provides a solution containing 90 mEq/l of sodium with a total osmolarity of 311 mOsm/l, has proven effective and without apparent adverse effects in worldwide use. It has been well established, however, that ORS solution does not reduce stool output or duration of diarrhoea.
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How many types of ORS are there?

A comparative study of three types of ORS in the management of diarrheal dehydration.
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What is the difference between ORS and ReSoMal?

At that time WHO guidance advised that children with SAM should be given a modified version of oral rehydration solution (ORS) called ReSoMal (rehydration solution for malnutrition), which has lower sodium, higher potassium and glucose and lower osmolarity than Old WHO ORS ( Table 2) 5, 6.
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Are osmolarity and osmolality the same?

Osmolarity and osmolality are frequently confused and incorrectly interchanged. Osmolarity refers to the number of solute particles per 1 L of solvent, whereas osmolality is the number of solute particles in 1 kg of solvent.
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What is composition of WHO ORS?

The composition of the new, reduced osmolarity ORS, as recommended by WHO, is as follows: • Sodium chloride—2.6 g. • Glucose (anhydrous)—13.5 g. • Potassium chloride—1.5 g. • Trisodium citrate dehydrate—2.9 g.
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Is ORS hypotonic or isotonic?

A hypotonic oral rehydration salts (ORS) solution with total osmolality of 224 mosmol/l was compared in an open clinical trial with an isotonic (osmolality 304 mosmol/l) ORS solution for the treatment of dehydration due to acute diarrhoea.
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Why is citrate added to ORS?

The citrate in ORS is needed for the treatment of acidosis, which occurs frequently with dehydration. Glucose is included in the solution principally to help the absorption of sodium and not as a source of energy.
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What does osmolarity mean?

The term osmolarity refers to the number of particles of solute per liter of solution, whereas the term osmolality refers to the number of particles of solute per kilogram of solvent.
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What is high osmolarity?

“Osmolality” refers to the concentration of dissolved particles of chemicals and minerals -- such as sodium and other electrolytes -- in your serum. Higher osmolality means you have more particles in your serum. Lower osmolality means the particles are more diluted.
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What osmolality means?

Osmolality is a test that measures the concentration of all chemical particles found in the fluid part of blood.
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Which is the best ORS in India?

Electral,India's No. 1, ORS,Oral Rehydration Solution Brand.
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Why glucose is added in ORS?

Glucose: A key agent in ORS, this ingredient helps the body absorb sodium through the cotransport system. It also helps to energize muscles and remedy fatigue. Other electrolytes: Nutrients like potassium, zinc, and magnesium play a crucial role in fluid balance.
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What is the best oral rehydration solution?

Pedialyte is an OTC rehydration drink for both children and adults. It's one of the most effective and safest treatments available for mild to moderate dehydration. Because it contains electrolytes, it's more effective than drinking only water if you've lost a lot of fluids.
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Why hypotonic is important?

Hypotonic solution: A solution that contains fewer dissolved particles (such as salt and other electrolytes) than is found in normal cells and blood. Hypotonic solutions are commonly used to give fluids intravenously to hospitalized patients in order to treat or avoid dehydration.
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Why is isotonic used to treat dehydration?

Isotonic IV solutions restore fluid volume because they fill the tissues and maintain fluid volume more effectively than hypertonic or hypotonic solutions.
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What IV fluid is best for dehydration?

For severe dehydration, start IV fluids immediately. If the patient can drink, give ORS by mouth while the IV drip is set up. Ringer's lactate IV fluid is preferred. If not available, use normal saline or dextrose solution.
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What's the difference between ORT and ORS?

Oral rehydration therapy (ORT) treats dehydration caused by severe diarrhea through the replacement of lost fluids. Oral rehydration solution (ORS) is one liter of water, six teaspoons of sugar, and a half teaspoon of salt. This simple mixture has saved millions of lives and costs just pennies.
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