Which symptom present in MS patients is the most difficult to address?

Fatigue, weakness, and imbalance were more severe for respondents with progressive forms of MS than for people with relapsing-remitting MS. Generally, respondents with greater mobility limitations reported worse fatigue, weakness, numbness, and pain.
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What is the most debilitating symptom of MS?

Fatigue is also among the most common symptoms, reported by at least 75% of MS patients at some point in the disease course. For many, fatigue is considered to be the single most debilitating symptom, surpassing pain and even physical disability.
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What do people with MS struggle with?

Summary. Multiple sclerosis (MS) is a disease of the central nervous system that can affect the brain, spinal cord and optic nerves. Common symptoms include fatigue, bladder and bowel problems, sexual problems, pain, cognitive and mood changes such as depression, muscular changes and visual changes.
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What are 4 clinical manifestations that most patients with multiple sclerosis present with?

Muscle stiffness or spasms. Severe weakness or paralysis, typically in the legs. Problems with bladder, bowel or sexual function. Cognitive problems, like forgetfulness or word finding difficulties.
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What is the most common symptoms associated with multiple sclerosis?

Some of the most common symptoms include:
  • fatigue.
  • vision problems.
  • numbness and tingling.
  • muscle spasms, stiffness and weakness.
  • mobility problems.
  • pain.
  • problems with thinking, learning and planning.
  • depression and anxiety.
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Less Common Symptoms -- National MS Society



What are some unusual symptoms of MS?

Here are some of the less common, more surprising symptoms that you might not be aware of.
  • Vertigo. Many people with MS experience dizziness, in which you feel light-headed or off-balance, notes the NMSS. ...
  • Speech Disorders. ...
  • Difficulty Swallowing. ...
  • Itching. ...
  • Hearing Problems. ...
  • Tremors. ...
  • Headache and Migraine. ...
  • Breathing Problems.
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Why are the symptoms of MS unpredictable?

The resulting damage to myelin, the protective layer insulating wire-like nerve fibers, disrupts signals to and from the brain. This interruption of communication signals causes unpredictable symptoms such as numbness, tingling, mood changes, memory problems, pain, fatigue, blindness and/or paralysis.
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Can MS cause irrational behavior?

While many with MS will experience depression or anxiety at some point, more rarely, some people experience changes to their emotions or behaviour that don't seem to make sense, or that they aren't able to control.
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Why is it so hard to get diagnosed with MS?

Tests for multiple sclerosis. Diagnosing MS is complicated because no single test can positively diagnose it. Other possible causes of your symptoms may need to be ruled out first. It may also not be possible to confirm a diagnosis if you have had only 1 attack of MS-like symptoms.
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What is the most common cause of MS exacerbation?

Exacerbations (relapses) are caused by inflammation in the central nervous system (CNS). The inflammation damages the myelin, slowing or disrupting the transmission of nerve impulses and causing the symptoms of MS.
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Are there obvious symptoms of MS?

Multiple sclerosis, a chronic disease of the central nervous system, is notable for its erratic and unpredictable symptoms. The obvious symptoms can include difficulty walking, loss of coordination, muscle spasms, weakness and changes in speech. But, not all symptoms are easily visible.
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What are the facial symptoms of multiple sclerosis?

Usually, MS facial twitching affects one side of your face at a time. And you may notice other facial symptoms first, like numbness, tingling, weakness, or other weird sensations. “People will usually say, 'My face feels swollen, but I look in the mirror and it's not swollen,'” Stoll says.
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What are the first physical signs of MS?

There are lots of symptoms that MS can cause, but not everyone will experience all of them.
  • fatigue.
  • numbness and tingling.
  • loss of balance and dizziness.
  • stiffness or spasms.
  • tremor.
  • pain.
  • bladder problems.
  • bowel trouble.
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Which symptoms do nearly all people with MS experience during the course of their disease?

Which symptom do nearly all people with MS experience during the course of their disease? Up to 90% of all people with MS experience fatigue.
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What are MS symptom triggers?

Multiple sclerosis (MS) triggers that worsen symptoms or cause a relapse can include stress, heart disease and smoking. While some are easier to avoid than others, maintaining a healthy lifestyle and overall health and wellness can have outsized benefits for MS patients.
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What is the hallmark of multiple sclerosis?

The pathologic hallmark of multiple sclerosis is multiple focal areas of myelin loss within the CNS called plaques or lesions, accompanied by variable gliosis and inflammation and by relative axonal preservation. Active multiple sclerosis lesions are infiltrated by macrophages containing myelin debris.
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What causes weakness in multiple sclerosis?

Damage to the nerve fibers (demyelination) in the spinal cord and brain that stimulate the muscles can also cause weakness. The muscles are not receiving the nerve impulses they require in order to work effectively – which often results in decreased endurance.
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Is MS anxiety symptoms?

MS can cause significant anxiety, distress, anger, and frustration from the moment of its very first symptoms. The uncertainty and unpredictability associated with MS is one of its most distressing aspects. In fact, anxiety is at least as common in MS as depression.
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What is primary and secondary fatigue in multiple sclerosis?

Primary fatigue is caused by MS damage in the brain and spinal cord. And lots of processes might be involved. One idea from researchers is that passing messages around nerve damage takes extra energy. Secondary fatigue is caused by living with MS symptoms like pain, or disturbed sleep.
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When do MS symptoms get worse?

Over time, symptoms stop coming and going and begin getting steadily worse. The change may happen shortly after MS symptoms appear, or it may take years or decades. Primary-progressive MS: In this type, symptoms gradually get worse without any obvious relapses or remissions.
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What are the symptoms of MS brain lesions?

MS brain lesions may appear on the brainstem—the lowest part of the brain right above the spinal cord. Among the symptoms that can appear with MS brainstem lesions are blurred or double vision, trouble swallowing, slurred speech, dizziness, coordination problems, weakness, and decreased sensation.
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What is the most common way to diagnose MS?

Brain MRI is often used to help diagnose multiple sclerosis.
...
Your doctor may then recommend:
  • Blood tests, to help rule out other diseases with symptoms like MS . ...
  • Spinal tap (lumbar puncture), in which a small sample of cerebrospinal fluid is removed from your spinal canal for laboratory analysis.
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What symptoms do MS spinal lesions cause?

Multiple sclerosis (MS) causes damage, called lesions, to parts of the central nervous system, including the spine.
...
Symptoms
  • pain and itching.
  • numbness or tingling.
  • weakness.
  • fatigue.
  • dizziness and vertigo.
  • sexual dysfunction.
  • trouble walking.
  • spasticity.
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What type of personality do people with multiple sclerosis have?

Regarding the five-factor model (FFM) that deals with five core dimensions—neuroticism, extraversion, openness, conscientiousness, and agreeableness [10]—MS patients usually show high neuroticism, loss of empathy, and low agreeableness, which are distinctive features of narcissism and histrionism.
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