Which solvent is best for extraction?

Methanol was identified as the most effective solvent for the extraction, resulting in the highest extraction yield (33.2%) as well as the highest content of phenolic (13.36 mg GAE/g DW), flavonoid (1.92 mg QE/g DW), alkaloid (1.40 mg AE/g DW), and terpenoids (1.25%, w/w).
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What are some commonly used solvent for extraction?

If you know something about the compound that needs extraction, one can choose a solvent. Methanol and ethanol are commonly used since they extract a wide range of compounds. Another set of solvents is hexane (or petroleum ether), followed by dichloromethane, ethyl acetate, methanol (or ethanol), and finally water.
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Is water the best solvent for extraction?

To extract polar compounds in extract it is best to use water, ethanol methanol or butanol while for non polar compounds diethyl ether, hexane or chloroform depending on the use of the estract. I believe these will give you good result. Water is always best solvent for living being.
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How do we select solvent for extraction?

The several criteria are:
  1. Distribution Coefficient. This is the ratio (at equilibrium) of the concentration of solute in the extract and raffinate phases. ...
  2. Selectivity (Separation Factor) ...
  3. Insolubility of Solvent. ...
  4. Recoverability. ...
  5. Density. ...
  6. Interfacial Tension. ...
  7. Chemical Reactivity. ...
  8. Viscosity, Vapour Pressure, Freezing Point.
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What is the most effective extraction method?

Solvent extraction is the most widely used method. The extraction of natural products progresses through the following stages: (1) the solvent penetrates into the solid matrix; (2) the solute dissolves in the solvents; (3) the solute is diffused out of the solid matrix; (4) the extracted solutes are collected.
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Which Solvent is the Best?



Why methanol is used for extraction?

The polarity of the solvent used will determine the kind of compounds that can be extracted. Most at times, methanol is a polar solvent used to extract bioactive compounds from extracts and has very good yields when compared to other solvents (methanol has better yields than ethanol).
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Is ethanol extraction better than CO2?

Ethanol extraction is flammable, but not nearly as much as light hydrocarbons such as butane and propane. However, for those that want peace of mind, CO2 can offer more safety than other extraction methods since carbon dioxide is not flammable and less toxic than ethanol.
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What is the choice of solvent?

A pair of solvents is chosen: one in which the compound is soluble (called the "soluble solvent"), and one in which the compound is insoluble (called the "insoluble solvent"). The two solvents must be miscible in one another so that their solubility with one another does not limit the proportions used.
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Why is ethanol a good solvent for extraction?

Ethanol Solubility

Ethanol, also referred to as Ethyl alcohol (EtOH), is a common solvent which closely reproduces chemical ratios when used during extraction processes. Alcohol allows extraction of both water soluble and oil soluble components.
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Why is hexane a good solvent for extraction?

Hexane is a chemical solvent that presents as a clear, odorless liquid that has a high evaporation rate and low boiling point, which makes hexane an ideal chemical for extraction. In addition to having the ideal properties for extraction hexane also produces no toxic fumes which is preferred for the safety of the user.
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Is ethanol a better solvent than methanol?

Methanol is the best solvent system to extract phytochemicals. Because methanol has high extractability in compare with Ethanol. methanol and its polarity work on vast number of phytochemicals including Polar and non polar compounds. the extractability we can assure atleast 50% on both side of the polarity.
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Why is acetone used for extraction?

If you are extracting THC to produce products that will be consumed or inhaled, an organic, non-toxic solvent like acetone is a great option for extraction. Acetone evaporates very quickly and has a low boiling point.
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Why are methanol and ethanol not used for extraction?

Ethanol, methanol, tetrahydrofuran (THF) and acetone are usually not suitable for extraction because they are completely miscible with most aqueous solutions.
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Why ethyl acetate is used for extraction?

Solvents like ethyl acetate are used in extraction processes because of its chemical and biological functions such as medium polarity and minimum cell toxicity. Ethyl acetate biphasic actions enables it to be used to extract both polar and non polar compounds.
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Why do we use different solvents for extraction?

It is because of the extractability and solubility of different plant extracts/ residues in different solvents as all of them are not extracted in a particular solvent. The best solvent can be selected for a particular plant-drug on the basis of its higher extractability percentage.
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Which is the best solvent?

Water has the ability to dissolve a large variety of substances. This is the reason why it is regarded as a good solvent. Furthermore, water is often referred to as the “universal solvent” because it is known to dissolve more substances than all other liquid solvents.
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Why is acetone a better solvent than ethanol?

Acetone is a good solvent due to its ability to dissolve both polar and nonpolar substances, while other solvents can only dissolve one or the other.
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What type of ethanol is used for extraction?

Ethanol used in the extraction processes is usually USP grade. This stands for United States Pharmacopeia and means the product is acceptable for food, drug, or medicinal use. Companies can also choose to use denatured ethanol. This type of ethanol has a component that is poisonous and is not suitable for consumption.
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Why is toluene a good solvent?

Toluene is a very good solvent because, unlike water, it can dissolve many organic compounds. In many commercial products, toluene is used as a solvent that is present in paint thinners, nail polish remover, glues, and correction fluid.
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Which pairs of solvents would make good extraction systems?

Water and dichloromethane and water and diethyl ether form immiscible two-component solvent systems that are ideal for solvent extraction.
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Why is dichloromethane a good solvent for extraction?

While dichloromethane isn't miscible with water, it is able to dissolve a wide range of organic compounds. These properties, combined with its volatility, makes DCM a highly effective solvent in many industrial processes.
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Is butane a good solvent?

Since butane has a boiling point of 30.2℉, it easily re-condenses without the use of extreme temperatures. This makes butane the solvent of choice for passive recovery. Butane tends to yield a more stable extract, as the polar terpenes are left behind.
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Is ethanol extraction better than butane?

Ethanol has a much higher boiling point than Butane or Propane making the recovery process generally slower and more difficult. Ethanol is limited in the products it can produce making items like shatter or “sauce” is nearly impossible.
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Is propane or butane better for extraction?

Propane has a lower boiling point than butane, allowing the leftover solvent to be easily removed. The main difference is between butane and propane is that propane runs at higher pressures. This makes it easier to strip larger plant molecules and often delivers less residue and higher levels of terpene.
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Is methanol a better solvent than water?

Methanol 100% is a good organic solvent to extract most of the compounds but it is not that polar compared to water. So combination of methanol-water will be good for most of the compounds from polar-non polar.
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