Which medication may lead to bruxism?

Bruxism is an under-recognised adverse drug reaction particularly associated with use of antipsychotics and selective serotonin reuptake inhibitors. A recent systematic review of case reports found it was most commonly reported with fluoxetine, venlafaxine and sertraline.
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Why do drugs cause bruxism?

Medication: Research shows that certain medications are known to cause bruxism, including those that are used to treat psychiatric conditions. 2 It's thought that these drugs cause changes in the central nervous system that lead to teeth grinding and jaw clenching.
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Do all antidepressants cause bruxism?

Although there aren't many antidepressants that don't cause bruxism, it might be worth it to ask your doctor if they can prescribe you something different, like the non-SSRI antidepressant Buspar which can boost dopamine without causing bruxism.
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What is the main cause of bruxism?

While stress is a main cause of bruxism in adults, that's not usually the case with children. Teeth grinding in children may come from: Allergies. Misaligned teeth.
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Does dopamine cause bruxism?

Acute use of dopamine precursors like L-dopa inhibits bruxism activity and chronic long term use of L-dopa results in increased bruxism activity. SSRIs (serotonin reuptake inhibitors) such as Prozac exert an indirect influence on the dopaminergic system and may cause bruxism after long-term use.
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The Cause And Cure Of Bruxism And Clenching By Dr Mike Mew



Can caffeine cause bruxism?

Caffeine links bruxism and coffee. The caffeine in coffee stimulates your muscles, which makes you grind harder and more often and causes further damage to your teeth, not to mention you won't get much sleep if you're grinding all night.
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Why do SSRIs cause bruxism?

It has been hypothesized that the mechanism for SSRI-induced bruxism may involve excessive serotonergic action on the meso-cortical neurons arising from the ventral tegmental area.
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Does Zoloft cause bruxism?

Commonly used antidepressant medications—including Prozac, Paxil and Zoloft—may cause bruxism and associated headaches, a new study shows.
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Can sertraline cause teeth clenching?

Bruxism may develop as an adverse reaction to antidepressant therapy, and is most likely to develop within 2–3 weeks of medication introduction or dose titration. This phenomenon may be seen in a variety of serotonergic antidepressants, and may be most associated with fluoxetine, sertraline, or venlafaxine.
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Do stimulants cause bruxism?

People taking stimulants may notice bruxism (teeth grinding and clenching) and a decrease in saliva, resulting in dry mouth (called xerostomia). These side effects do not affect everyone, but for those who find them bothersome, there are ways to manage these problems.
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What drugs cause jaw problems?

Bisphosphonates — such as alendronate (Fosamax, Binosto), risedronate (Actonel, Atelvia), ibandronate (Boniva) and zoledronic acid (Reclast, Zometa) — and denosumab (Prolia, Xgeva) have been linked to osteonecrosis of the jaw and atypical femoral fractures.
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Can certain medications cause TMJ?

Drugs such as Prozac, Lunesta, benzodiazepines, oral contraceptives (migraine) and so forth can cause or exacerbate TMD symptoms.
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Can citalopram cause teeth grinding?

We commonly come across patients on Citalopram, Fluoxetine, Sertraline, and Venlafaxine displaying side effects of bruxism. Apart from discontinuation of the drug there is reported role of Buspirone as an antidote for this side effect.
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Does amitriptyline cause teeth grinding?

Low doses of amitriptyline (a tricyclic antidepressant) were found to be ineffective against SB, 189, 190 and SSRI medications (eg, fluoxetine, sertraline, paroxetine) actually increased tooth grinding and clenching.
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Can antidepressants cause TMJ?

Depression, ADHD, tinnitus and TMJ all cluster together, meaning that when someone has one, they are at increased risk for the rest. It is also true that antidepressants have occasionally been reported to cause tinnitus, and we know that they can cause teeth grinding, which can worsen TMJ.
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Does Prozac cause teeth grinding?

In the last few years, research has shown that Selective Serotonin Reuptake Inhibitor (SSRI) medications such as Prozac, Paxil, Zoloft, and Celexa may cause clenching and grinding of the teeth in patients who have never done this before and will increase these behaviors (both frequency and intensity) in those known to ...
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Can Lexapro cause teeth grinding?

Bruxism may also be an uncommon side effect of some antidepressant medications, particularly selective serotonin reuptake inhibitors. Some are citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac), paroxetine (Paxil) and sertraline (Zoloft).
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Why does lexapro cause jaw clenching?

It's thought that SSRIs can cause bruxism by indirectly lowering dopamine levels. Dopamine inhibits certain movements including jaw clenching. Treatment with other agents that affect dopaminergic neurotransmission such as antipsychotics, amphetamines, and levodopa are also associated with bruxism.
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Can Zoloft cause TMJ?

A number of medications that are used to treat these conditions can also trigger jaw problems, including: Prozac (fluoxetine), Zoloft (sertraline)
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Do sleeping pills cause bruxism?

Medication Side Effects

Drugs for sleep, anxiety or depression all may raise your risk of bruxism slightly. Antidepressants, in particular, have a high rate of this kind of bruxism development.
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What vitamin deficiency causes teeth grinding?

After analyzing the data, the authors found an association between deficient levels of vitamin D and the severity of bruxism. More individuals reporting moderate and severe bruxism were deficient in vitamin D concentrations than those experiencing no symptoms or other levels of tooth clenching or grinding, they wrote.
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Does nicotine cause bruxism?

If you grind your teeth when you're stressed, nervous or upset, vaping can make things worse. Nicotine is a muscle stimulant and can cause or worsen bruxism.
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Does GERD cause bruxism?

After adjustment, GERD was identified as a risk factor of bruxism. Bruxism with reflux symptoms for extensive time-periods was associated with severe tooth wear for the whole dentition (odds ratio, 4.70, 95% confidence interval, 2.04–10.83).
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What are the most common side effects of citalopram?

Citalopram may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
  • nausea.
  • diarrhea.
  • constipation.
  • vomiting.
  • stomach pain.
  • heartburn.
  • decreased appetite.
  • weight loss.
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Can drugs cause bruxism?

Bruxism is an under-recognised adverse drug reaction particularly associated with use of antipsychotics and selective serotonin reuptake inhibitors. A recent systematic review of case reports found it was most commonly reported with fluoxetine, venlafaxine and sertraline.
Takedown request   |   View complete answer on ncbi.nlm.nih.gov
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