Which antidepressant is best?

"In the short-term, for acute depression, antidepressants seem to work modestly," said study author Dr.
...
When the researchers checked which depression drugs were tolerated the best, these topped the list:
  • Celexa (citalopram)
  • Lexapro (escitalopram)
  • Prozac (fluoxetine)
  • Trintellix (vortioxetine)
  • Zoloft (sertraline)
Takedown request   |   View complete answer on webmd.com


What is the best antidepressant with the least side effects?

Selective serotonin reuptake inhibitors (SSRIs).

These medications generally cause fewer bothersome side effects and are less likely to cause problems at higher therapeutic doses than other types of antidepressants are.
Takedown request   |   View complete answer on mayoclinic.org


What are the top three antidepressants?

Selective serotonin reuptake inhibitors (SSRIs) are the most prescribed type of antidepressant and include:
  • Fluoxetine.
  • Citalopram.
  • Sertraline.
  • Paroxetine.
  • Escitalopram.
Takedown request   |   View complete answer on magazine.medlineplus.gov


What are the top five antidepressants?

Top 5 antidepressants to treat depression
  • Citalopram.
  • Escitalopram.
  • Fluoxetine.
  • Fluvoxamine.
  • Paroxetine.
  • Sertraline.
Takedown request   |   View complete answer on medicinenet.com


What are the top 10 best antidepressants?

Their top 12 most popular and effective antidepressants were:
  • Celexa (citalopram)
  • Wellbutrin (bupropion)
  • Paxil (paroxetine)
  • Savella (milnacipran)
  • Prozac (fluoxetine)
  • Cymbalta (duloxetine)
  • Luvox (fluvoxamine)
  • Vestra (reboxetine)
Takedown request   |   View complete answer on sunrisehouse.com


Which antidepressant is right for you? | Ben's Mental Health Story | Mind



What is the number 1 prescribed antidepressant?

Zoloft is the most commonly prescribed antidepressant; nearly 17% of those surveyed in the 2017 antidepressant use study reported that they had taken this medication.
Takedown request   |   View complete answer on verywellmind.com


What's the safest antidepressant?

Among the newer antidepressants, bupropion and venlafaxine were associated with the highest case fatality rates. In addition, among SSRIs, citalopram and fluvoxamine appeared to be related to higher mortality rates in overdose, whereas fluoxetine and sertraline were the safest [188].
Takedown request   |   View complete answer on karger.com


What is the newest and best antidepressant?

29 (HealthDay News) -- Sertraline (Zoloft) and escitalopram (Lexapro) are the best of 12 new-generation antidepressants, while reboxetine is the least effective, a new analysis shows. The Italian researchers reviewed 117 studies that included more than 25,000 patients with major depression to come to this conclusion.
Takedown request   |   View complete answer on medicinenet.com


Which antidepressant works the fastest?

Ketamine, by far the best-studied of these medications, is notable for its very rapid antidepressant effects. In patients with treatment-resistant MDD, ketamine has produced initial reductions in depressive symptoms within two hours, with peak effects at 24 hours. Ketamine may also rapidly reduce suicidal thoughts.
Takedown request   |   View complete answer on sciencedaily.com


What is the best antidepressant for energy and motivation?

Prozac/Fluoxetine

It gives people more energy than other antidepressants which may not work well for someone with insomnia as well as depression. That being said, for those with low energy, it can be helpful. Fluoxetine treats many mental health issues which includes depression, OCD, and panic disorders.
Takedown request   |   View complete answer on northpointrecovery.com


What is better Prozac or Zoloft?

In a double-blind, clinical trial, both Zoloft and Prozac improved depression based on different scores for depression and anxiety as well as sleep. While both SSRIs were found to be effective, Zoloft was found to have lower severity of side effects.
Takedown request   |   View complete answer on singlecare.com


Is Zoloft better than Lexapro?

A 2014 study published in International Clinical Psychopharmacology suggested that Lexapro may be more effective and better tolerated than Zoloft or Paxil. Lexapro has different binding site interactions which may lead to better efficacy and tolerability.
Takedown request   |   View complete answer on singlecare.com


What are the newest antidepressants?

The Food and Drug Administration (FDA) recently approved two new antidepressant medications that represent new approaches to treating depression: brexanolone and esketamine.
Takedown request   |   View complete answer on perks.optum.com


Is there a medication that treats both depression and anxiety?

Selective serotonin reuptake inhibitors (SSRIs) are a class of medications that have a broad therapeutic range. They can be used to treat anxiety disorders, depression, or, in some cases, both at the same time.
Takedown request   |   View complete answer on singlecare.com


Which is best antidepressant for anxiety?

SSRIs and SNRIs are often the first-line treatment for anxiety. Common SSRI brands are Celexa, Lexapro, Luvox, Paxil, and Zoloft, and common SNRI brands are Pristiq, Cymbalta, and Effexor XR. Pros: They are effective for a lot of people and they have a solid safety profile.
Takedown request   |   View complete answer on bannerhealth.com


What is the best antidepressant for anxiety with the least side effects?

As of this writing, some of the anxiety medications with the fewest reported side effects and least risk of side effects include:
  • Most Benzodiazepines (Xanax, Valium)
  • Bupropion (Wellbutrin)
  • Citalopram (Celexa - SSRI)
  • Paroxetine (Paxil - SSRI)
Takedown request   |   View complete answer on calmclinic.com


What is the strongest antidepressant?

The most effective antidepressant compared to placebo was the tricyclic antidepressant amitriptyline, which increased the chances of treatment response more than two-fold (odds ratio [OR] 2.13, 95% credible interval [CrI] 1.89 to 2.41).
Takedown request   |   View complete answer on evidence.nihr.ac.uk


What antidepressant is best for severe depression?

Doctors often start by prescribing an SSRI. These drugs are considered safer and generally cause fewer bothersome side effects than other types of antidepressants. SSRIs include citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac), paroxetine (Paxil, Pexeva), sertraline (Zoloft) and vilazodone (Viibryd).
Takedown request   |   View complete answer on mayoclinic.org


Is Zoloft a good antidepressant?

Zoloft (sertraline) is a good and safe antidepressant that is also used to treat other psychiatric disorders such as panic disorder, post-traumatic stress disorder and obsessive compulsive disorder.
Takedown request   |   View complete answer on goodrx.com


What antidepressant is stronger than Zoloft?

In a study on patients who suffer from major depression, the drug Effexor was more likely than Prozac or Zoloft to result in full recovery. Researchers suspect Effexor is more effective because it acts on two different brain chemicals that transmit messages and are thought to control mood.
Takedown request   |   View complete answer on webmd.com


Is Prozac better than Lexapro?

When considering Prozac vs Lexapro, both medications are approved to treat major depressive disorder (MDD). A 2014 study found that Lexapro was more effective than Prozac in treating severe periods of depression.
Takedown request   |   View complete answer on tryminded.com


What is the best antidepressant for anxiety and panic attacks?

Selective serotonin reuptake inhibitors (SSRIs).

Generally safe with a low risk of serious side effects, SSRI antidepressants are typically recommended as the first choice of medications to treat panic attacks.
Takedown request   |   View complete answer on mayoclinic.org


Which antidepressants cause the most weight loss?

Of these three medications, bupropion (Wellbutrin) is the most consistently associated with weight loss. Several studies, including a 2019 meta-analysis of 27 studies, found that bupropion (Wellbutrin) was the only commonly used antidepressant associated with weight loss.
Takedown request   |   View complete answer on khealth.com


What are the 3 types of antidepressants?

There are several different types of antidepressants.
  • Selective serotonin reuptake inhibitors (SSRIs) ...
  • Serotonin-noradrenaline reuptake inhibitors (SNRIs) ...
  • Noradrenaline and specific serotonergic antidepressants (NASSAs) ...
  • Tricyclic antidepressants (TCAs) ...
  • Serotonin antagonists and reuptake inhibitors (SARIs)
Takedown request   |   View complete answer on nhs.uk


Is Lexapro a good antidepressant?

Lexapro (escitalopram) is good for treating depression and anxiety. It's generally well-tolerated and has fewer drug interactions than other antidepressants.
Takedown request   |   View complete answer on goodrx.com