Which antidepressant causes the most weight gain?

Tricyclic antidepressants such as amitriptyline and tetracyclic antidepressants such as mirtazapine are linked to the most weight gain.
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Which antidepressants do not cause weight gain?

Some antidepressants may be less likely to affect weight. Effexor and Serzone generally do not cause weight gain, while Wellbutrin can cause weight loss.
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Which causes more weight gain Prozac or Zoloft?

That being said, one study published in 2016 in the Journal of Clinical Medicine found that Zoloft can lead to an overall greater weight gain than Prozac when taken long-term. The study found that people taking Prozac for two years gained an average of 4.6 pounds.
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Do antidepressants make everyone gain weight?

Weight gain is a possible side effect of nearly all antidepressants. However, each person responds to antidepressants differently. Some people gain weight when taking a certain antidepressant, while others don't.
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Can antidepressants cause permanent weight gain?

The most commonly prescribed form of antidepressant medication, selective serotonin reuptake inhibitors (SSRIs) have been associated with weight loss in short-term use, but may cause weight gain when used long term.
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Why do you gain weight with antidepressants and mood stabilizers?



Does everyone gain weight on Lexapro?

Lexapro is the brand name for a drug called escitalopram, which is a treatment for anxiety and depression. Taking Lexapro may cause a person to gain a small amount of weight. Less commonly, it can cause weight loss. A healthful diet and regular exercise can help to prevent unwanted changes in weight.
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Can Zoloft help weight loss?

Weight gain is a common complaint of patients receiving antidepressant drug treatment. The antidepressant sertraline, a selective serotonin uptake inhibitor, has been reported to promote weight loss.
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Is sertraline making me fat?

Zoloft (sertraline) may lead to a small weight gain ranging from 1% to 1.6% of initial body weight when used over 6 months to 1 year. For example, in a 150 lb (68 kg) person, this would equal an added 1.5 to 2.4 lbs (0.7 to 1.1 kg) of weight.
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Does Lexapro help you lose weight?

There are some reports that people begin to lose weight when first taking Lexapro, but this finding is not well supported by research studies. Another study found that Lexapro didn't reduce the obsessive-compulsive symptoms linked to binge-eating disorder, but it did reduce weight and body mass index.
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Why does Zoloft make you gain weight?

One theory is that antidepressants such as sertraline may stimulate your appetite and make you feel hungrier than normal by affecting your ability to suppress the urge to eat.
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Is Prozac better than Wellbutrin?

Is Wellbutrin or Prozac better? Wellbutrin and Prozac are similarly effective for treating depression. The best antidepressant is the one that causes the least side effects and is more cost effective, depending on the situation. Wellbutrin causes less sexual side effects and weight gain than SSRIs like Prozac.
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Which is better Zoloft or Lexapro?

A 2014 study published in International Clinical Psychopharmacology suggested that Lexapro may be more effective and better tolerated than Zoloft or Paxil. Lexapro has different binding site interactions which may lead to better efficacy and tolerability.
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Which is stronger Zoloft or Prozac?

Which is More Effective? Both Prozac and Zoloft are considered powerful mental health medications, comparably effective at treating depression and reducing anxiety for the patients who take them. A few clinical trials suggest that Zoloft may have less serious side effects than Prozac.
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Is Wellbutrin a good antidepressant?

Wellbutrin has been found to be at least as effective as other popularly prescribed antidepressant medication. There is also less chance of weight gain, sleepiness, and sexual dysfunction than with other forms of treatment. It may even work actively against sexual dysfunction resulting from previous antidepressant use.
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Is Effexor better than Wellbutrin?

Effexor and Wellbutrin are both effective drugs that treat depression. Effexor is better than Wellbutrin for treating anxiety disorders that are experienced alongside depression. However, compared to Wellbutrin, Effexor may cause more sexual side effects, such as abnormal ejaculation and impotence.
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How does Wellbutrin cause weight loss?

It stimulates noradrenaline, dopamine, and (less-so) serotonin receptors. This gives you more energy, suppresses your appetite, and enhances your mood. Stress increases cortisol and ghrelin which stimulate your appetite. Dopamine and noradrenaline suppress your appetite.
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Which is better effexor or Lexapro?

The results found that both Effexor and Lexapro were similarly effective at treating depression, and both were more effective than many other antidepressant medications. However, Effexor's side effect profile may make it more difficult to tolerate than Lexapro.
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Is Prozac better than Lexapro?

When considering Prozac vs Lexapro, both medications are approved to treat major depressive disorder (MDD). A 2014 study found that Lexapro was more effective than Prozac in treating severe periods of depression.
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Can Lexapro cause rapid weight gain?

Antipsychotic drugs, antidepressants , and mood stabilizers are common drugs that have the most potential to increase weight gain. All 12 of the leading antidepressants, including fluoxetine (Prozac), sertraline (Zoloft), and escitalopram (Lexapro), make gaining weight more likely.
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How can I lose weight on antidepressants?

Increasing both aerobic exercise and strength training, ideally four times a week for a minimum of 30 to 45 minutes, can increase muscle tone and metabolism and reduce fat stores. Regular exercise has also been shown to reduce risk for depression relapse when combined with a stable medication regimen.
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How can I lose weight after antidepressants?

How to lose weight after antidepressants
  1. Change medication. Some antidepressants aren't linked to weight gain. ...
  2. Look at your lifestyle. One study on SSRI use and weight gain found that weight gain was more likely in people who also had a Western diet, were sedentary, and smoked⁸. ...
  3. Get active. ...
  4. Get a good night's sleep.
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How fast is weight loss on Wellbutrin?

How long does it take for Wellbutrin to work for weight loss? In people who lose weight as a side effect of Wellbutrin, it is possible to notice weight changes within eight weeks. However, Wellbutrin is not a weight-loss drug and may not produce consistent results when taken for this purpose.
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Does Wellbutrin help with weight loss?

Wellbutrin (bupropion) is a prescription medication for depression and smoking cessation. Bupropion can cause weight loss in some people, so it's sometimes prescribed as a weight loss medication in the form of Contrave (a combination drug of bupropion and naltrexone).
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Does Wellbutrin cause weight gain?

Weight changes are considered a side effect for both Wellbutrin XL and Wellbutrin SR. Studies of Wellbutrin XL show that 23% of people taking a dose of 150 to 300 mg per day lost 5 pounds or more. In the same studies, 11% of people gained more than 5 pounds.
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What is the difference between Lexapro and Wellbutrin?

While both Wellbutrin and Lexapro treat depression, they are not the same type of drug, Wellbutrin works by blocking the reuptake of dopamine and norepinephrine in the neuronal synapse, while Lexapro blocks the reuptake of serotonin. All of these neurotransmitters play a role in mood and affect.
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