Where is theophylline found?

Theophylline is naturally found in cocoa beans. Amounts as high as 3.7 mg/g have been reported in Criollo cocoa beans. Trace amounts of theophylline are also found in brewed tea, although brewed tea provides only about 1 mg/l, which is significantly less than a therapeutic dose.

Is theophylline found in chocolate?

Chocolate (cocoa) contains mostly theobromine and also caffeine and theophylline in low concentrations.

Does green tea have theophylline?

Theophylline is found naturally in black and green tea, green coffee, unsweetened natural cocoa, and mate (sometimes called Yerba mate, Jesuits' tea, or Paraguayan tea).

Does tea have theophylline?

Tea also contains two substances related to caffeine: theobromine and theophylline. Finally, it provides a rather unique amino acid called L-theanine, which has some very interesting effects on the brain.

How is theophylline manufactured?

Theophylline is a xanthine alkaloid, a methylxanthine chemically related to caffeine and theobromine. Along with caffeine, it is an active constituent of tea (Camellia sinensis), but it is commercially produced in pharmaceutical manufacture by chemical synthesis.

Theophylline (Uniphyl) - Pharmacist Review - Uses, Dosing, Side Effects

Is theophylline still made?

Major has discontinued theophylline extended-release tablets. Teva has had theophylline extended-release tablets temporarily unavailable for several years. Theophylline 24-hour extended-release presentations are available from Mylan, Rhodes, and Endo Pharmaceuticals.

Who makes theophylline?

Theophylline is available under the brand names Elixophyllin, Theo-24, Theo-Dur, and others. Lannett Company, Inc., Pfizer Inc., and Heritage Pharmaceuticals Inc. are pharmaceutical companies that manufacture Theophylline.

What foods is theophylline found in?

Theophylline is found in black tea and to a lesser extent in green coffee, cocoa cotyledon and dried mate. Theophylline is synthesized on an industrial scale and is used principally in pharmaceutical preparations. Per-caput daily intake of theophylline from black tea in the USA has been estimated to be 0.14 mg.

How much theophylline is in green tea?

Theophylline (1,3-dimethylxanthine, TP) is a purine alkaloid that is found in the three most popular ingredients in the world: tea, (21) coffee, (22) and cocoa. (23) There are reportedly about 1.8 mg/g TP in tea leaves, (24) 0.04 mg/mL in black coffee, (25) and 2.0 mg/g in cocoa powder.

What foods have theobromine?

Theobromine is consumed in cocoa and chocolate beverages and in various forms of chocolate-based foods. Theobromine is also present in small amounts in green coffee beans, tea and mate.

Who shouldn't drink green tea?

Precautions. Pregnant and breastfeeding women, children under the age of 2 and people with kidney disorders, heart conditions, stomach ulcers and psychological problems should also avoid taking green tea. People with glaucoma, anemia, liver disease, osteoporosis and diabetes should also avoid it.

Are caffeine and theophylline similar?

Caffeine is a drug that is very similar to theophylline. Theophylline is a bronchodilator drug that is taken to open up the airways in the lungs and therefore relieve the symptoms of asthma, such as wheezing, coughing and breathlessness.

How much theophylline is in a cup of tea?

Natural occurrences. Theophylline is naturally found in cocoa beans. Amounts as high as 3.7 mg/g have been reported in Criollo cocoa beans. Trace amounts of theophylline are also found in brewed tea, although brewed tea provides only about 1 mg/l, which is significantly less than a therapeutic dose.

Does Coca Cola contain theobromine?

Possible effects of cola extracts were also found out. Cola contains catechins, theobromine, and tannins.

Does white chocolate contain theophylline?

Chocolate contains caffeine and theobromine, both of which are members of the methylxanthine group of compounds. Another member of this class is theophylline.

What chocolate has the most theobromine?

Theobromine concentrations are higher in certain types of chocolate. Higher cacao percentage chocolate (progressively darker) has higher theobromine levels, with raw cacao powder being the highest at 20mg/g. Milk chocolate contains 2mg theobromine per 1g of chocolate. Dark chocolate contains on average 9mg/g^​21,25​.

Which drug is found in coffee?

Caffeine is a drug that stimulates (increases the activity of) your brain and nervous system. Caffeine is found in many drinks such as coffee, tea, soft drinks and energy drinks.

Does black tea have theobromine?

Total theobromine was highest in black teas (1.64 and 1.69 mg/g) and least in oolong teas (0.65 and 0.71 mg/g). Caffeine and theobromine were not detected in either herbal tea samples, and theophylline was not detected in any tea tested.

Why does tea make you pee more than coffee?

Tea Is A Natural Diuretic

The caffeine in tea is the main culprit for excess peeing. Caffeine is a well known diuretic that makes you want to pee a lot.

How much theobromine is in green tea?

The content of methylxanhines was determined in green tea infusions by HPLC method. The content of caffeine varied from 19,78 to 27,22 mg/g DW. Theobromine was found in the concentrations between 1,22 and 6,04 mg/g and theophilline in concentrations between 0,52 and 1,28 mg/g DW.

What is the generic name for theophylline?

Theophylline is available under the following different brand names: Theo 24, Theochron, Elixophyllin, aminophylline, and Uniphyl.

Do tea and coffee have the same amount of caffeine?

With a coffee shop on every corner, catch-ups over coffee or a good ole coffee morning, it's no wonder that coffee is the strong favourite. But, interestingly, tea has more caffeine in it per mg. See, tea leaves have around 3.5% caffeine in them whereas unbrewed coffee beans have only around 1.1-2.2% caffeine.

Why has theophylline been discontinued?

The Department of Health and Social Care (DHSC) has issued a supply disruption alert (SDA) stating that, Merck, the manufacturer of Slo-phyllin® (theophylline) capsules, has discontinued production of all strengths of this medicine due to manufacturing issues. There are no safety concerns with the product.

Is theophylline available over the counter?

Theophylline and phenobarbital previously were active ingredients in nonprescription asthma products; however, both are now classified as prescription-only products.

Is there a substitute for theophylline?

Abstract: Doxofylline, which differs from theophylline in containing the dioxalane group at position 7, has comparable efficacy to theophylline in the treatment of respiratory diseases, but with an improved tolerability profile and a favorable risk-to-benefit ratio.