Where does lymphoma spread to first?

NHL usually starts in an area of lymph nodes. When it spreads to an organ or tissue outside of the lymph nodes, it is called extranodal spread.
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Where is lymphoma most likely to spread?

Lymphoma most often spreads to the liver, bone marrow, or lungs.
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Where does lymphoma usually begin?

Lymphoma is cancer that begins in infection-fighting cells of the immune system, called lymphocytes. These cells are in the lymph nodes, spleen, thymus, bone marrow, and other parts of the body.
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Does lymphoma spread quickly?

Non-Hodgkin lymphoma grows and spreads at different rates and can be indolent or aggressive. Indolent lymphoma tends to grow and spread slowly, and has few signs and symptoms. Aggressive lymphoma grows and spreads quickly, and has signs and symptoms that can be severe.
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How do you know if lymphoma has spread?

Stage 4 lymphoma occurs when cancer has spread to a distant part of the body outside of the lymphatic system, such as the spinal cord, lungs, or liver.
...
Symptoms
  1. enlarged lymph nodes under the skin.
  2. fatigue.
  3. chills.
  4. loss of appetite.
  5. itching.
  6. a persistent cough.
  7. shortness of breath.
  8. chest pain.
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Signs and symptoms of lymphoma - Mayo Clinic



What are the warning signs of lymphoma?

Signs and symptoms of lymphoma may include:
  • Painless swelling of lymph nodes in your neck, armpits or groin.
  • Persistent fatigue.
  • Fever.
  • Night sweats.
  • Shortness of breath.
  • Unexplained weight loss.
  • Itchy skin.
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What is the most common early symptom of lymphoma?

The most common sign of lymphoma is a lump or lumps, usually in the neck, armpit or groin. These lumps are swollen lymph nodes, sometimes known as 'glands'. Usually, they're painless. Fatigue is different to normal tiredness.
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Which is worse non-Hodgkin's lymphoma or Hodgkin's lymphoma?

Non-Hodgkin lymphoma is the seventh most diagnosed cancer, accounting for an estimated 72,500 cases in 2016. More than 86 percent of patients diagnosed with Hodgkin lymphoma survive five years or more. About 70 percent of patients diagnosed with non-Hodgkin lymphoma survive five years or more.
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How long could you have lymphoma without knowing?

These grow so slowly that patients can live for many years mostly without symptoms, although some may experience pain from an enlarged lymph gland. After five to 10 years, low-grade disorders begin to progress rapidly to become aggressive or high-grade and produce more severe symptoms.
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What can be mistaken for lymphoma?

Conditions that non-Hodgkin Lymphoma is commonly misdiagnosed as include:
  • Influenza.
  • Hodgkin's lymphoma.
  • Cat scratch fever.
  • HIV.
  • Infections.
  • Mononucleosis.
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What triggers lymphoma?

Causes of lymphoma

In most cases, there is no known cause for lymphoma. However, for a few types of lymphoma, scientists have identified a cause: Most cases of gastric MALT lymphoma are caused by a common bacterial infection called Helicobacter pylori. Usually, Helicobacter pylori causes stomach ulcers and indigestion.
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Does lymphoma show up in blood work?

Most types of lymphoma can't be diagnosed by a blood test. However, blood tests can help your medical team find out how lymphoma and its treatment are affecting your body. They can also be used to find out more about your general health.
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Can lymphoma spread to other parts of the body?

Lymphoma can spread rapidly from the lymph nodes to other parts of the body through the lymphatic system. As cancerous lymphocytes spread into other tissues, the immune system cannot defend against infections as effectively.
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What type of lymphoma is not curable?

Lymphoplasmacytic lymphoma or Waldenstrom macroglobulinemia.

It's found mainly in the bone marrow, lymph nodes, and spleen. This type of lymphoma can't be cured.
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Where does non-Hodgkin's lymphoma metastasis to?

Regardless of how quickly they grow, all non-Hodgkin lymphomas can spread to other parts of the lymph system if not treated. Eventually, they can also spread to other parts of the body, such as the liver, brain, or bone marrow.
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What does lymphoma fatigue feel like?

People often describe lymphoma fatigue (or treatment-related fatigue) as feeling: Extremely tired. Weak. Exhausted.
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Can you gain weight with lymphoma?

Weight gain is also extremely common among patients with prostate cancer, as well as lymphoma, multiple myeloma and chronic leukemia.
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Can you feel well with lymphoma?

Signs and Symptoms of Hodgkin Lymphoma. You or your child can have (HL) and feel perfectly well. But HL often causes symptoms or changes that should be checked by a doctor.
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What does lymphoma feed on?

Earlier studies hinted at the same thing. Now, Zheng says, it seems clear that a major factor in the mysterious rise of non-Hodgkin's lymphoma is a diet high in meat, saturated fats, dairy products, and eggs and low in fiber, fruits, and vegetables.
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Is lymphoma a terminal?

Survival for all non-Hodgkin lymphomas

Generally, for people with non-Hodgkin lymphoma in England: around 80 out of every 100 people (around 80%) survive their cancer for 1 year or more after they are diagnosed. around 65 out of every 100 people (around 65%) survive their cancer for 5 years or more after diagnosis.
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Which is worse leukemia or lymphoma?

Which is more aggressive: leukemia or lymphoma? The survival rate for lymphoma is higher than leukemia. According to the Leukemia and Lymphoma Society, the 5-year survival rate of all leukemias combined is 65.8 percent.
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Where do you itch with lymphoma?

Cytokines can irritate nerve endings in the skin, which can in turn cause persistent itching. Many individuals experience this itchiness in their hands, lower legs or feet, while others feel it throughout their entire body. Patients often report that the itching tends to worsen while they are lying in bed at night.
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How is lymphoma detected early?

Even though there is no routine lymphoma screening test, early detection is possible for both Hodgkin and non-Hodgkin lymphoma. The typical diagnostic process involves a physical exam and medical history, along with a biopsy and cell/blood tests.
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What blood test results indicate lymphoma?

Complete blood count (CBC).

This test measures the number of blood cells in a sample, including red blood cells, white blood cells, and platelets. A low level of red blood cells, white blood cells or platelets may indicate that the lymphoma is present in the bone marrow and/or blood.
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