When is the best time of year to test a horse for Cushing's?

If a horse is showing symptoms of Cushing's Disease and has a normal ACTH level, then we recommend either re-testing ACTH levels during Mid-August to Mid-February, or a TRH stimulation test.
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How much does an equine Cushings test cost?

The test is performed Monday-Saturday, with results in one business day; the cost is $29.00 with a $6.00 accession fee. One drawback to this test is the need for multiple measurements at 15 and 19 hours post injection of dexamethasone.
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What age does Cushing's start in horses?

The disease primarily affects those over the age of 10, with 19 being the average age at diagnosis. It can be quite prevalent in aged equine populations.
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What is the best hay to feed a horse with Cushings?

Alfalfa averages 10-15% NSC, and oat hay is very high, averaging 22%. Alfalfa can be a good option for a horse with Cushings if they are a hard time holding their weight because it is more calorie-dense than grass hay.
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Can you reverse Cushings in horses?

The Right Medicine PPID cannot be cured, but its effects can be controlled with medication and management. The drug most commonly used to treat horses with PPID is pergolide mesylate, a dopamine agonist that helps to regulate the pituitary gland.
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Equine Cushings Disease: Challenges of Diagnosis and Treatment



Can horses with Cushings eat grass?

Pasture grasses can have a high NSC content, especially during the spring and fall seasons, and the risk of colic and laminitis is greater when horses are on pasture. Since laminitis and founder are more common in horses with Cushing's disease, pasture grazing should be severely limited or totally avoided.
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What happens if Cushings is left untreated in horses?

If a horse has untreated Cushing's Disease, it is more likely to develop laminitis and the laminitis will be more difficult to control. If an equine has any of the clinical signs suggestive of Cushing's, a blood sample can be taken to check ACTH levels in the blood.
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What should I feed my senior horse with Cushings?

Increased energy requirements can be met by feeding alfalfa (lucerne) hay or chaff, super-fibers such as beet pulp and soy hulls, or a low- to moderate-NSC feed. Feeds that are higher in fat (greater than 6%) are preferred as they are less reliant on carbohydrates for energy.
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How quickly does Prascend work?

Clinical improvement is usually expected within 6-12 weeks of starting Prascend treatment, however the length of time between initiation of treatment to being able to see a response can vary from one horse or pony to another.
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Can you feed oats to horses with Cushings?

Even though oats are the grain lowest in sugar and starch, at around 45 to 50% starch they are still far too high in starch for horses on a low sugar and starch diet, eg insulin resistant horses, horses prone to laminitis, those with disorders like Cushings or PSSM etc, as well as many horses who are prone to ulcers, ...
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How can you tell if a horse has Cushings?

Signs of Cushing's syndrome include:
  • Failure or later shedding of the winter coat that may become really long, matted and curly especially around the legs.
  • Excessive sweating.
  • Increased drinking and urination.
  • Lethargy and poor performance.
  • A pot-bellied appearance.
  • Loss of muscle and topline.
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How do I know if my horse has Cushings disease?

Also known as equine Cushing's disease, PPID can cause signs that are subtle and easy to miss, such as a decrease in activity. The disease can progress to include loss of muscle mass and hair coat changes. “They may seem quieter than normal, perhaps duller,” notes Nicholas Frank, DVM, Ph.
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How long does a horse live with Cushing's?

Well-managed horses should live about five to seven years or more past diagnosis. In severely affected horses, however, laminitis and recurrent infections are time-consuming and expensive to manage and can shorten the horse's anticipated life expectancy dramatically.
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Does a horse with Cushings need medication?

How do you treat Equine Cushing's disease? Treatment is fairly simple. It consists of an oral medication (Pergolide) in the form of a tablet given once daily. PRASCEND is a FDA-approved formulation of pergolide.
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Is Cushing's painful for horses?

As long as horses with Cushing's disease are treated and monitored closely for any signs of pain (due to laminitis) or other abnormal characteristics of decreased quality of life, they are not thought to be suffering.
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How common is Cushing's disease in horses?

Equine Cushing's disease, also known as PPID, is thought to affect 20% of horses over the age of 15, and is the 5th most common disease syndrome recognised in horses and ponies in the UK*.
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How long can horses be on PRASCEND?

24-month stability at labeled storage conditions which allows for consistent, reliable dosing. PRASCEND is for use in horses only.
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Can you PRASCEND every other day?

Giving 0.5 mg every other day - the datasheet states that Prascend should be given once daily. As the average half life of pergolide has been found to be around 6 hours in horses (Abra Wright Pharmacokinetics of pergolide in normal mares, MSc thesis 2009), extending the time between doses seems counter-intuitive.
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What are the side effects of PRASCEND in horses?

Side effects

Prascend® is well tolerated in horses. Potential adverse reactions in horses include inappetence, transient anorexia and lethargy, mild central nervous system signs (e.g. mild depression, mild ataxia and mild hyperexcitability), diarrhoea and colic. These signs are usually mild and transient in nature.
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Can Cushings in horses be treated naturally?

Good hoof-care combined with nutritional management and the application of other modalities, including acupuncture and Chinese and Western herbs, can complete the healing process. The successful treatment of equine Cushing's syndrome is one of the best examples of treating a disease using the holistic approach.
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Does Cushing's shorten a horse's life?

Cushing's disease is not a death sentence. Despite the fact that there is no cure, there are several management practices that can keep an affected horse in use and in good health for many years following diagnosis.
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How long does it take for pergolide to work in horses?

Pergolide does not accumulate in the horse's body, and steady levels of pergolide are realized within three days of starting treatment; Pergolide is cleared from the system quickly, with a half-life less than 12 hours; and.
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Do all Cushings horses get laminitis?

Equine Cushing's cases always develop laminitis if they live long enough. They may become immunosuppressed and subject to a variety of parasitic or infectious agents such as helminthiasis or pneumonia. Many cases show muscle loss and become polydipsic and polyphagic; they may be diabetic.
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How do you prevent Cushing's disease in horses?

Although Cushing's disease cannot always be prevented, there are precautions you can take to lower the risk. “The most important thing is to keep your horse's weight down, providing proper nutrition, which means to feed him only what he really needs,” Langer says. Sugar intake should be minimized.
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What is a high ACTH level in horses?

However very high levels (>300pg/mL) are still highly suggestive of ECS and a normal level in the autumn (<100 pg/mL) is more likely to be truly negative. Horses with EMS may have elevated ACTH due to the stress of their laminitic condition but levels will still not be as high as expected with ECS.
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