What's the difference between Moderna and Pfizer?

The interval between Moderna doses is 28 days; for the Pfizer vaccine, it's 21 days. Each dose of Pfizer's contains 30 micrograms of vaccine. Moderna went with a much larger dose of vaccine, 100 micrograms. It means the company is using a little more than three times as much vaccine per person as Pfizer is.
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What are the possible side effects of the Moderna COVID-19 vaccine?


Possible side effects: Pain, redness, swelling in the arm where the shot was administered; tiredness, headache, muscle pain, chills, fever, nausea throughout the rest of the body. If any of these side effects occur, they should go away in a few days.

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Is it safe to take the Moderna, Pfizer-BioNTech, or J&J COVID-19 vaccine during pregnancy?

No safety concerns were found in animal studies: Studies in animals receiving a Moderna, Pfizer-BioNTech, or Johnson & Johnson (J&J)/Janssen COVID-19 vaccine before or during pregnancy found no safety concerns in pregnant animals or their babies.
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Is there a difference between the Moderna COVID-19 booster and Moderna third shot?


In the case of Moderna, the booster dose is only half of the original dose. Unlike boosters, third/additional doses of COVID-19 vaccines are for people who received the complete starter series of vaccines but then their immune systems didn't have a good enough response.

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Do mRNA Pfizer and BioNTech vaccines largely prevent severe disease from the COVID-19 Omicron variants?

Pfizer Inc. and BioNTechs Covid-19 vaccine appears to largely prevent severe disease from the coronavirus omicron variants sublineages BA. 4 and BA.
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Pfizer v. Moderna: Is One Better Than the Other?



Does the COVID-19 vaccine reduce the risk of getting "Long COVID"?

Reseach is showing that people who are vaccinated, even with just one dose, tend to have lower rates of long COVID-19 after catching the virus than those who are unvaccinated.
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Does the COVID-19 booster vaccine protect against the Omicron variant?


In adult populations, the protection conferred by two vaccine doses against Covid-19 wanes (more against milder infection than against severe disease) and is lower for omicron than for delta. However, a booster dose increases protection, including protection against omicron.

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Can you mix and match COVID-19 booster shots?

The FDA has authorized the use of mix-and-match booster doses for currently available COVID-19 vaccines based on the results of a NIAID-supported study.

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Is there a COVID-19 second booster for Pfizer and Moderna?


The FDA and CDC have authorized a second booster from Pfizer and Moderna for people with certain immune deficiencies. This includes solid organ transplant recipients and those with conditions that give them an equally reduced ability to fight infections and other diseases.

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Do COVID-19 booster shots cause worse side effects?


If you experienced side effects when you were vaccinated initially, you may wonder if you'll have any noticeable symptoms in response to your booster shot. While you may have some side effects, they should be no worse than what you experienced originally and may well be milder.

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Is the COVID-19 vaccine safe for pregnancy?

Vaccination is recommended for pregnant women to prevent COVID-19, including severe illness and death. COVID-19 vaccination is safe and effective when administered during pregnancy
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Can you have the mRNA COVID-19 vaccine if pregnant?


Data have clearly shown that receiving an mRNA COVID-19 vaccine during pregnancy reduces the risk for infection, severe illness and death from COVID-19 among people who are pregnant.

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What can you tell us about pregnancy after receiving the Pfizer COVID-19 shot?


What can you tell us about that? Results from published studies suggest there is no increased risk of first trimester pregnancy loss for patients who receive any of the three vaccines that currently have emergency use authorization: Pfizer, Moderna and Johnson & Johnson-Janssen.

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What are some side effects of the COVID-19 vaccine?


Although COVID-19 vaccination and booster doses reduce the risk of serious illness, they don't guarantee you will avoid getting infected. All vaccines can cause immune responses such as arm rashes, swollen lymph nodes, low-grade fever, soreness, and fatigue.
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What are the possible side effects of the Moderna and Pfizer COVID-19 vaccines?


Possible side effects: Pain, redness, or swelling at the site where the shot was administered, and/or tiredness, headache, muscle pain, chills, fever, or nausea throughout the rest of the body. If these side effects occur, they should go away in a few days. A few side effects are serious, but rare.

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When do COVID-19 vaccine side effects appear?


You probably experienced COVID-19 vaccine side effects fairly quickly when you had your initial injections. The same is true for COVID-19 vaccine booster shots: Most people notice side effects within the first 24 hours. The symptoms typically only last a day or two. Some people don't notice any side effects.

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How long does the protection from Pfizer and Moderna's COVID-19 booster vaccine last?


The most recent research from the CDC suggests that protection from the Pfizer and Moderna COVID-19 vaccines starts to fade around 4 months after a booster dose.

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Can you mix and match the vaccines for your mRNA (Pfizer or Moderna) primary vaccination series?


No, vaccines used for the primary vaccination series should be same. However, if the mRNA vaccine product given for the first two doses is not available or is unknown, either Pfizer-BioNTech or Moderna COVID-19 vaccine (mRNA COVID-19 vaccines) may be administered.

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How long is the stability of the Pfizer-BioNTech COVID-19 vaccine?

Pfizer-BioNTech has submitted data to FDA supporting the stability of their COVID-19 vaccine when stored for up to one month (31 days) at 2°-8°C (standard refrigerator temperature).
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Can you mix and match Pfizer and Moderna COVID-19 vaccine?


Through the FDA's authorization and the CDC's recommendation, heterologous boosting—aka “mixing and matching”—is allowed with a single dose of any of the authorized COVID-19 vaccine boosters. For example, those who got Johnson & Johnson's one-dose series can receive a booster shot from Moderna or Pfizer

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Are people 50 and older eligible to receive a second COVID-19 booster vaccine in the US?

In late May, the Centers for Disease Control and Prevention strengthened its recommendations to say people 50 or older should get a second booster shot if at least four months have passed since their first booster.
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How long does COVID-19 rebound usually last?

How long will a rebound last? In the cases that have been described, rebound symptoms improved and/or positive tests became negative within 3 days for most people.
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Is the COVID-19 Omicron variant more transmissible than previous variants?

The good news was that the new variant caused less severe illness and death than Delta. But it was also highly transmissible—more contagious than any variant that came before it.
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Are COVID-19 vaccines effective against COVID-19 delta variant?

In fact, COVID-19 cases have increased over 300% nationally from June 19 to July 23, 2021, driven by Delta variant.

The best way to stop the spread of Delta is to get vaccinated against COVID-19. Vaccines are preventing severe illness, hospitalization, and death, and are effective against the Delta variant.

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Does the COVID-19 vaccine reduce the transmission of the Delta variant?

This study confirms that COVID-19 vaccination reduces the risk of delta variant infection and also accelerates viral clearance in the context of the delta variant. However, this study unfortunately also highlights that the vaccine effect on reducing transmission is minimal in the context of delta variant circulation.
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