What's better Pepcid or Prilosec?

Key takeaways: Famotidine (Pepcid) and omeprazole (Prilosec) are two medications used to treat gastroesophageal reflux disease (GERD). Both medications are effective in helping to manage GERD symptoms. Famotidine kicks in faster, but omeprazole works better and provides longer-lasting relief.
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What is the difference between Prilosec and Pepcid?

Pepcid and Prilosec belong to different drug classes. Pepcid (famotidine) is an H2-blocker and Prilosec is a proton pump inhibitor (PPI). Pepcid and Prilosec are available over-the-counter (OTC) and in generic form.
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Which is safer famotidine or omeprazole?

Famotidine has no major contradictions with other medications. Omeprazole, however, has many interactions with medications including HIV medications, clopidogrel, methotrexate, and certain antibiotics. Because of this, it may be safer for you to take famotidine if you are on many medications.
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Is there something better than Prilosec?

When comparing Nexium to Prilosec, clinical trials found that Nexium tended to outperform Prilosec and other PPIs. Nexium was able to offer the best acid control as well as faster symptom relief. Even so, both medicines are effective and one may work better for another based on individual health factors.
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Is Prilosec the best for acid reflux?

Yes, Prilosec is a good option for acid reflux. In clinical studies, Prilosec helped to heal ulcers and improve symptoms.
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Pepcid vs. Prilosec - What Should I Take for Heartburn?



Is it OK to take Prilosec every day?

Prilosec OTC is to be used once a day, every day for 14 days as a course of treatment. Do not take for more than 14 days or more oftent han every 4 months unless directed by a doctor.
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Can I take Prilosec and Pepcid together?

No, Nexium, Prilosec, and Pepcid should not be taken together. Scientists and Clinicians do not recommend taking both a PPI and an H2-blocker at the same time as they have overlapping mechanisms of actions despite working at different stages of production.
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What is the safest antacid to take long term?

According to Dr. Ghouri, Prilosec OTC “is usually sufficient in controlling symptoms in a majority of [heartburn] cases” and has been the #1 Doctor Recommended frequent heartburn relief medicine for 14 years.
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Is there a safer alternative to Prilosec?

There are other medications that can be used instead of PPIs in the treatment of conditions like acid reflux. H2 blockers include: Cimetidine (Tagamet) Ranitidine (Zantac)
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Why does Prilosec work so well?

It works by decreasing the amount of acid your stomach makes. It relieves symptoms such as heartburn, difficulty swallowing, and cough. This medication helps heal acid damage to the stomach and esophagus, helps prevent ulcers, and may help prevent cancer of the esophagus.
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Can you take Pepcid everyday?

Official answer. Famotidine (brand name: Pepcid AC, Zantac 360) should not be used for longer than 14 days if you are treating heartburn symptoms.
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What are the dangers of famotidine?

Check with your doctor right away if you have the following symptoms: confusion, delirium, hallucinations, disorientation, agitation, seizures, or unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness. These are more likely to occur if you are older or if you have a kidney disease.
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Is it OK to take famotidine every day?

Do not take more than two tablets, capsules, or chewable tablets of over-the-counter famotidine in 24 hours and do not take over-the-counter famotidine for longer than 2 weeks unless your doctor tells you that you should.
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Which is the most effective antacid?

Calcium Carbonate [CaCO3] – Calcium Carbonate (chalk) is the most potent usable antacid. It can completely neutralize stomach acid.
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What medicine is stronger than Prilosec?

There is some evidence that Nexium provides more effective acid control, lasts for longer, and works faster than Prilosec; however, some studies have failed to find a difference between the two medicines and the American College of Gastroenterology states that there are no major differences between PPIs when used to ...
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Which Pepcid is best for acid reflux?

When you need heartburn relief fast, try Maximum Strength PEPCID AC® with 20 mg of famotidine. You can also take Maximum Strength PEPCID AC® before a meal in order to help prevent symptoms from starting in the first place. Maximum Strength PEPCID AC® is not indicated to treat GERD.
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Who should not use Prilosec?

liver problems. a type of kidney inflammation called interstitial nephritis. subacute cutaneous lupus erythematosus. systemic lupus erythematosus, an autoimmune disease.
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Why was Prilosec taken off the market?

They may contain unacceptable levels of a potential cancer-causing substance known as NDMA, or N-Nitrosodimethylamine. In some samples tested by the FDA, the impurity appears to increase over time, especially when stored at higher temperatures.
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Who should not take Prilosec?

Who should not take Omeprazole?
  • diarrhea from an infection with Clostridium difficile bacteria.
  • inadequate vitamin B12.
  • low amount of magnesium in the blood.
  • liver problems.
  • a type of kidney inflammation called interstitial nephritis.
  • subacute cutaneous lupus erythematosus.
  • systemic lupus erythematosus, an autoimmune disease.
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Why can't you take Pepcid long term?

Increased risk of bone fracture: Increased gastrin production as a result of taking PPIs can inhibit calcium absorption, making bones more fragile. Heart Attack: It's recently been discovered that the risk of heart attack in adults is increased by as much as 20% with the long term use of PPIs.
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What are the new warnings for famotidine?

Check with your doctor right away if you have the following symptoms: confusion, delirium, hallucinations, disorientation, agitation, seizures, or unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness. These are more likely to occur if you are older or if you have a kidney disease.
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Why can't you take Prilosec for more than 14 days?

You shouldn't take OTC omeprazole for longer than 14 days without a healthcare provider's OK. Prescription omeprazole is often taken for 4 to 8 weeks, depending on what you're treating. For some conditions, it's taken for even longer. Taking omeprazole for too long can lead to serious side effects.
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Is Pepcid good for acid reflux?

Famotidine (Pepcid AC) is a histamine-2 (H2) antagonist that's used to treat conditions that cause too much stomach acid to build up, such as heartburn and stomach or intestinal ulcers (sores).
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Is Tums or Pepcid better?

Studies have shown that bismuth subsalicylate and calcium carbonate are commonly used to treat indigestion because of their acid-reducing effects. Compared with H2 blockers like Pepcid (famotidine) and Zantac (ranitidine), Tums works faster and relieves symptoms for a shorter period of time.
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Can you take Pepcid in the morning and Prilosec at night?

Yes, you could take omeprazole in the morning and famotidine at night but there are not many studies investigating this approach.
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