What works better than metformin?

Insulin remains the most effective therapy to lower glucose, particularly in comparison to most oral medicines for type 2 (including metformin).
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What is the most effective medication for type 2 diabetes?

Metformin (Fortamet, Glumetza, others) is generally the first medication prescribed for type 2 diabetes. It works primarily by lowering glucose production in the liver and improving your body's sensitivity to insulin so that your body uses insulin more effectively.
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What works as well as metformin?

Studies show that taking berberine can lower blood sugar levels to a similar extent as the popular diabetes drug metformin ( 4 ).
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What is the best medicine to control blood sugar?

What Are the Best Drugs to Treat Diabetes?
  1. Insulin (long- and rapid-acting) ...
  2. Metformin (biguanide class) ...
  3. Glipizide (sulfonylurea class) ...
  4. Glimepiride (sulfonylurea class) ...
  5. Invokana (sodium glucose cotransporter 2 inhibitor class) ...
  6. Jardiance (SGLT2 class)​​​​​​​ ...
  7. Januvia (dipeptidyl peptidase 4 inhibitor)​​​​​​​
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What is the new pill for diabetes?

FRIDAY, Sept. 20, 2019 (HealthDay News) -- A new pill to lower blood sugar for people with type 2 diabetes was approved by the U.S. Food and Drug Administration on Friday. The drug, Rybelsus (semaglutide) is the first pill in a class of drugs called glucagon-like peptide (GLP-1) approved for use in the United States.
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Twice as Effective as Metformin!



Is Rybelsus better than metformin?

The bottom line. Metformin has been used to treat diabetes for a long time, while Rybelsus was recently approved in 2019. Both medications are effective for lowering blood sugar levels. Metformin is often the first-choice medication for this use.
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Is there another drug to replace metformin?

The currently available medications in this class are Adlyxin, Bydureon, Byetta, Ozempic, Rybelsus, Trulicity, and Victoza. Side effects of taking a GLP-1 receptor agonist may include: Nausea. Vomiting and diarrhea (usually decreases over time)
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Is berberine better than metformin?

In the regulation of lipid metabolism, berberine activity is better than metformin. By week 13, triglycerides and total cholesterol in the berberine group had decreased and were significantly lower than in the metformin group (P<0.05).
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Is Ozempic better than metformin?

Metformin has an average rating of 6.9 out of 10 from a total of 611 ratings on Drugs.com. 56% of reviewers reported a positive effect, while 18% reported a negative effect. Ozempic has an average rating of 5.9 out of 10 from a total of 641 ratings on Drugs.com.
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How can I get my A1C down quickly?

Since exercise prompts your muscles to take up sugar from your bloodstream, it helps your blood sugar levels drop more quickly after you eat a meal. As you make exercise a regular habit, you'll see a downward trend in your A1c numbers. Never miss your meds. You can reliably lower your A1c through diet and exercise.
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What should I do if metformin isn't working?

What to Do If Metformin Isn't Working
  • Actos (pioglitazone)
  • DPP-4I inhibitors, including Januvia (sitagliptin), Tradjenta (linagliptin), Onglyza (saxagliptin), and Nesina (alogliptin)
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Is Farxiga better than metformin?

Farxiga has an average rating of 4.5 out of 10 from a total of 129 ratings on Drugs.com. 28% of reviewers reported a positive effect, while 51% reported a negative effect. Metformin has an average rating of 6.9 out of 10 from a total of 611 ratings on Drugs.com.
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Is Trulicity or Ozempic better?

In the SUSTAIN 7 trial, Ozempic® was proven superior to Trulicity® in A1C reduction, A1C control, and weight reduction in adults with type 2 diabetes. Ozempic® is not indicated for weight loss.
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What is the new weight loss injection?

The U.S. Food and Drug Administration on Friday announced the approval of pharmaceutical giant Novo Nordisk's Wegovy (semaglutide) injection for adults who either have obesity or are overweight and have at least one weight-related condition such as high blood pressure, type 2 diabetes, or high cholesterol.
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Which is better Jardiance or Ozempic?

Compared to Jardiance (once-daily SGLT-2 inhibitor pill): The highest dose of oral Ozempic (14 mg) lowered A1C more than Jardiance: 1.3% decrease vs. 0.8% decrease. Average weight loss was about 10 pounds for oral Ozempic and 8 pounds for Jardiance.
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Can you substitute berberine for metformin?

In the case that is refractory or intolerable to metformin, berberine may be used as an alternative or additive agent to increase tolerance and minimize the side effects.
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Who should take berberine?

The people who stand to benefit the most are individuals with type 2 diabetes and metabolic syndrome. However, it may also be useful as a general protection against chronic disease, as well as an anti-aging supplement. If you use supplements, then berberine may be one of the top ones to include in your arsenal.
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Does berberine reduce belly fat?

Berberine inhibits gluconeogenesis in the liver, can modulate bacteria in the gut associated with obesity, and has been shown to decrease lipid (cholesterol) levels (5). Berberine has also been shown to assist weight and body fat loss by inhibiting the enzyme lipoprotein lipase, which increases fat storage (6).
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Is glipizide better than metformin?

Another comparative trial found that metformin provided better blood sugar control than glipizide. Those taking metformin in the study had better fasting plasma glucose levels than glipizide after 24, 36, and 52 weeks. Those taking metformin also had a lower HbA1c level than those taking glipizide after 52 weeks.
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How can I reverse diabetes permanently?

“There is no permanent cure for diabetes, because the cells that produce insulin have been damaged and the underlying genetic factors remain,” Lucas says. “The patient does maintain an increased susceptibility to recurrence of diabetes, so lifestyle interventions must be continued.”
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Which is better Ozempic or Rybelsus?

If you have heart disease, your doctor may recommend Ozempic instead of Rybelsus. Ozempic is approved to decrease the risk of major heart problems in people with type 2 diabetes and heart disease.
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Is Jardiance better than Rybelsus?

Jardiance has an average rating of 5.3 out of 10 from a total of 280 ratings on Drugs.com. 40% of reviewers reported a positive effect, while 42% reported a negative effect. Rybelsus has an average rating of 5.9 out of 10 from a total of 133 ratings on Drugs.com.
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Is Rybelsus the same as Trulicity?

Trulicity and Rybelsus are both GLP-1 receptor agonist medications used to treat type 2 diabetes mellitus. Although similar, they are different medications that contain different active ingredients. Dulaglutide in Trulicity and semaglutide in Rybelsus. The two medications may also affect you differently.
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What is cheaper Ozempic or Trulicity?

Average prices for Ozempic and Trulicity prices are similar, but Ozempic is usually slightly more expensive. Whilst Ozempic and Trulicity are similar GLP-1 receptor agonist medications used to treat Type 2 diabetes, there are differences between them.
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Which is better Ozempic or Victoza?

Ozempic and Victoza are both used (along with diet and exercise) to help lower blood sugar levels in adults with type 2 diabetes. Both drugs have been found to be effective for this use. One study found that Ozempic may be slightly better than Victoza at lowering blood sugar.
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