What were your first myasthenia gravis symptoms?

Myasthenia gravis most commonly affects muscles that control eye and eyelid movement, so the first symptoms you notice may be eyelid drooping and/or blurred or doubled vision. Most will go on to develop weakness in other muscle groups within one or two years.
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What are the most common early symptoms of myasthenia gravis?

Common symptoms of myasthenia gravis include:
  • droopy eyelids.
  • double vision.
  • difficulty making facial expressions.
  • problems chewing and difficulty swallowing.
  • slurred speech.
  • weak arms, legs or neck.
  • shortness of breath and occasionally serious breathing difficulties.
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What is an initial symptom in myasthenia gravis?

In about 15% of people with myasthenia gravis, the first symptoms involve face and throat muscles, which can: Impair speaking. Your speech might sound soft or nasal, depending on which muscles have been affected. Cause difficulty swallowing. You might choke easily, making it difficult to eat, drink or take pills.
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Does myasthenia gravis come on suddenly?

What are the symptoms of myasthenia gravis? Initial symptoms of MG often come on suddenly. The neuromuscular disease causes your muscles to get weaker when you're active. Muscle strength returns when you rest.
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Where does myasthenia gravis start?

In myasthenia gravis, muscle weakness often first appears in the muscles of the face, neck and jaw. The arm and leg muscles are affected later.
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Myasthenia Gravis MADE EASY - Cause, Symptoms, Diagnosis and Treatment of MG - Animation



What mimics myasthenia gravis?

Beware: there are other diseases that mimic myasthenia gravis. A number of disorders may mimic MG, including generalized fatigue, amyotrophic lateral sclerosis (ALS), Lambert-Eaton myasthenic syndrome, botulism, penicillamine-induced myasthenia, and congenital myasthenic syndromes.
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Which patient is most likely to have myasthenia gravis?

It most commonly impacts young adult women (under 40) and older men (over 60), but it can occur at any age, including childhood. Myasthenia gravis is not inherited nor is it contagious.
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Can you have mild myasthenia gravis?

Myasthenia gravis can range from mild to severe. In some cases, symptoms are so minimal that no treatment is necessary. Even in moderately severe cases, with treatment, most people can continue to work and live independently.
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What are the symptoms of weak eye muscles?

What Are the Symptoms?
  • Sore or irritated eyes.
  • Trouble focusing.
  • Dry or watery eyes.
  • Blurred or double vision.
  • Increased sensitivity to light.
  • Pain in the neck, shoulders, or back.
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Can myasthenia gravis symptoms come and go?

Myasthenia gravis (or myasthenia) is a condition that causes weakness in the voluntary muscles (the muscles we can control). The weakness can come and go, and vary from mild to severe.
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How quickly does MG progress?

Over a longer term, the symptoms of MG usually progress, reaching maximum or near-maximum severity within one to three years of onset in most people. In about 15% of people, the disease remains ocular, but in most it becomes oculobulbar or generalized.
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Are there different stages of myasthenia gravis?

Myasthenia gravis (MG), a neuromuscular disease characterized by weakness and fatigue, is typically divided into five types: generalized, congenital, ocular, juvenile, and transient neonatal myasthenia gravis, depending on time of disease onset, the cause of the neuromuscular dysfunction, and the muscle groups affected ...
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Can you have myasthenia gravis without ptosis?

Conclusion: Although the hallmark findings of MG are ptosis and eye muscle palsy with variability, MG may present without ptosis, affect nonstriated muscles, and/or manifest either as a nonstrabismic vergence anomaly or as comitant nonvariable strabismic deviation.
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What can trigger myasthenia gravis?

Myasthenia crisis may be caused by a lack of medicine or by other factors, such as a respiratory infection, emotional stress, surgery, or some other type of stress. In severe crisis, a person may have to be placed on a ventilator to help with breathing until muscle strength returns with treatment.
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Why is myasthenia gravis worse in the evening?

In patients with myasthenia gravis, the body's immune system mistakenly interferes with the muscles' receptors for acetylcholine. When these receptors cannot work properly, the affected muscles tire easily. The amount of weakness typically fluctuates and may be worse at the end of the day.
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Why does myasthenia gravis affect the eyes first?

It's very common for myasthenia gravis to affect the muscles that control eye movement. In fact, for a large percentage of people, eye-related changes are one of the first symptoms of myasthenia gravis. Because of the lack of signals to the nerves, changes to the eyes may include: Drooping eyelids.
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Does myasthenia gravis cause back pain?

Although the underlying cause of pain in MG is unknown, it could be related to muscle weakness and changes in posture. For example, weakness in the muscles of the head may change the way a person stands, leading to neck or back pain. MG also impacts a person's quality of life and mental health.
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Does myasthenia gravis cause tingling?

MG can indeed often mimic MS – tingling arms and legs, general fatigue, slurred speech – all of these symptoms can be attributed to the deterioration caused by MS.
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Does myasthenia gravis cause shaking?

In patients with MG, this test will lead to shaking or a gradual drooping of arms, hands, or fingers.
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What is late onset myasthenia gravis?

Late-onset MG is defined herein as the onset of the disease after the age of 50 years in a patient with no clinical or paraclinical evidence of a thymoma but, quite often, with immunological findings similar to those found in patients with thymoma.
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Can you live a normal life with MG?

Many people with MG can live fairly normal lives. The first one to three years – when various symptoms appear – often are the most difficult. It can take time to work through various treatments to find what works best for you. MG is called the “snowflake disease” because its symptoms differ for every patient.
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Can you have myasthenia gravis with a normal blood test?

Approximately 85% of people diagnosed with MG have AChR autoantibodies present in their blood tests. For people with generalized MG, some will not have AChR antibodies present in the blood, but a small percentage will test positive for anti-MuSK (muscle-specific kinase) antibodies.
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What feature do almost all patients with myasthenia gravis have?

Patients with myasthenia gravis come to the physician complaining of specific muscle weakness and not of generalized fatigue. Ocular motor disturbances, ptosis or diplopia, are the initial symptom of myasthenia gravis in two-thirds of patients; almost all had both symptoms within 2 years.
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Does myasthenia gravis affect the stomach?

Well, this was definitely mine. Side effects of many of the medications to treat myasthenia gravis include stomach upsets, stomach cramps, and other things I sometimes think are worse than the symptoms they are treating.
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Can myasthenia gravis go away?

Myasthenia gravis is a chronic condition, but it can go into remission—meaning the signs and symptoms of myasthenia gravis disappear—lasting for several years. Most people with myasthenia gravis are able to gain muscle strength through medication or immunotherapy.
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