What tests are done to detect COVID-19?

There are two types of COVID-19 diagnostic tests:
  • Molecular tests, such as polymerase chain reaction (PCR) tests.
  • Antigen tests, often referred to as rapid tests.
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What is the most accurate diagnostic test to detect COVID-19?


Reverse transcription polymerase chain reaction (RT-PCR)-based diagnostic tests (which detect viral nucleic acids) are considered the gold standard for detecting current SARS-CoV-2 infection.

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Which COVID-19 tests are more accurate PCR or antigen tests?


PCR tests are more accurate than antigen tests. "PCR tests are the gold standard for detecting SARS-CoV-2," says Dr. Broadhurst. "It is the most accurate testing modality that we have.

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What are the different types of viral tests?


Viral Test Types

  • Laboratory tests can take days to complete and include RT-“PCR” tests and other types of nucleic acid amplification tests (NAATs).
  • Rapid Point-of-Care tests can be performed in minutes and can include antigen tests, some NAATs, and other tests.



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What is a PCR test in the context of COVID-19 testing?

A PCR test stands for polymerase chain reaction test. This is a diagnostic test that determines if you are infected by analyzing a sample to see if it contains genetic material from the virus.
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RT-PCR made EASY - Reverese Transcriptase PCR for detection and test of Viral DNA



Why PCR is better than the rapid COVID-19 test?


“PCR tests are more reliable and accurate due to testing the specific genetic material of the virus, eliminating the interference from other viruses,” said Heather Seyko, a Laboratory Services manager for OSF HealthCare.

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How accurate are COVID-19 PCR tests?

PCR tests are very accurate when properly performed by a health care professional, but the rapid test can miss some cases.
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What is the difference between a molecular test and rapid antigen tests for COVID-19?


Molecular tests are generally more accurate and mostly processed in a laboratory, which takes longer; antigen tests—or “rapid tests”—are processed pretty much anywhere, including at home, in doctors' offices, or in pharmacies.

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What is the CDC viral testing tool for COVID-19?


Need additional help? CDC's Viral Testing Tool is an online, mobile-friendly tool that asks a series of questions, and provides recommended actions and resources based on a user's responses.

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What is the difference between the IgM and IgG antibodies tests for COVID-19?

Both SARS-CoV-2 IgM and IgG antibodies may be detected around the same time after infection. However, while IgM is most useful for determining recent infection, it usually becomes undetectable weeks to months following infection; in contrast, IgG is usually detectable for longer periods.
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When should you take a COVID-19 PCR test instead of a rapid antigen test?


“PCR would be chosen where there is a low likelihood of having the virus, but we want to be certain the patient doesn't have it. Antigen would be chosen if there is a high probability the patient has the virus (i.e. is experiencing symptoms), and we need to screen the patient as positive or negative,” Heather said.

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How long can someone test positive on a COVID-19 rapid antigen test?

Two-plus years into the COVID-19 pandemic, scientists still arent sure how long people who catch coronavirus remain infectious, The Wall Street Journal reports. Some people keep testing positive with rapid tests beyond five days, and some even test positive after 10 days, the newspaper reported.
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What is the accuracy of the COVID-19 antigen test?


If possible, taking an at-home rapid COVID-19 test the day of the event is ideal. While these tests aren't 100% accurate, a negative result strongly suggests that you're not contagious at that particular time.

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Are molecular or rapid COVID-19 tests more accurate?


Molecular tests are generally more accurate and mostly processed in a laboratory, which takes longer; antigen tests—or “rapid tests”—are processed pretty much anywhere, including at home, in doctors' offices, or in pharmacies.

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How accurate are home COVID-19 tests?

Even though demand for COVID-19 tests greatly overwhelmed supply earlier in the pandemic, rapid home tests are more available today. While home tests provide a quick, accurate result, the flip side is that many test results are no longer reported to health authorities.
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Are CT scans helpful for diagnosing COVID-19?

Along with laboratory testing, chest CT scans may be helpful to diagnose COVID-19 in individuals with a high clinical suspicion of infection.
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How accurate is the BinaxNOW rapid test compared to PCR?

Accuracy: The BinaxNOW test correctly gave a positive result 84.6% of the time compared to PCR. In the same study, the test correctly gave a negative result 98.5% of the time.

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What is the Lucira COVID-19 All-in-One test kit?

The Lucira COVID-19 All-In-One Test Kit is a single-use test kit intended to detect the novel coronavirus SARS-CoV-2 that causes COVID-19. This test is authorized for prescription home use with self-collected nasal swab samples in individuals aged 14 and older who are suspected of COVID-19 by their healthcare provider.
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How accurate is the at-home QuickVue rapid COVID-19 test?


Quidel QuickVue rapid test Two lines mean a positive result. Accuracy: For people with symptoms, the QuickVue test correctly gave a positive result 83.5% of the time. It also correctly gave a negative result 99.2% of the time.

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What are COVID-19 antigen tests?

Antigen tests are commonly used in the diagnosis of respiratory pathogens, including influenza viruses and respiratory syncytial virus. The U.S. Food and Drug Administration (FDA) has granted emergency use authorization (EUA) for antigen tests that can identify SARS-CoV-2.
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What is the COVID-19 Molecular Laboratory Developed Test?

The Molecular LDT COVID-19 Authorized Test is designed, for use in a single laboratory, to detect the virus that causes COVID-19 in respiratory specimens, for example nasal or oral swabs.
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What does a false-positive COVID-19 antigen test result mean?


A false-positive antigen test result means that the test says the person has COVID-19 but they are actually do not have COVID-19.

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Can a COVID-19 RT-PCR test be falsely negative?


RT-PCR tests are not perfect, Alland said. “After the first week of infection, there is a decline in virus shedding in the respiratory tract, where tests can become falsely negative,” he said.

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What are consequences of a false negative COVID-19 test?

Risks to a patient of a false negative test result include: delayed or lack of supportive treatment, lack of monitoring of infected individuals and their household or other close contacts for symptoms resulting in increased risk of spread of COVID-19 within the community, or other unintended adverse events.
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Is it possible to get a false positive test result for COVID-19?

It's possible to have a positive test result even if you never had any symptoms of COVID-19 . False-positive test results can occur. It may be that the test detected antibodies to a coronavirus closely related to the COVID-19 virus or that the test quality was flawed.
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