What puts you at risk for having a baby with Down syndrome?

Advancing maternal age.
A woman's chances of giving birth to a child with Down syndrome increase with age because older eggs have a greater risk of improper chromosome division. A woman's risk of conceiving a child with Down syndrome increases after 35 years of age.
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What makes you high risk of having a baby with Down syndrome?

One factor that increases the risk for having a baby with Down syndrome is the mother's age. Women who are 35 years or older when they become pregnant are more likely to have a pregnancy affected by Down syndrome than women who become pregnant at a younger age.
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How do you prevent Down syndrome during pregnancy?

April 17, 2003 -- Taking folic acid supplements before and during early pregnancy may not only help prevent neural tube defects in babies, but it may also reduce the risk of Down syndrome.
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What causes Down syndrome during pregnancy?

TRISOMY 21 (NONDISJUNCTION)

Down syndrome is usually caused by an error in cell division called “nondisjunction.” Nondisjunction results in an embryo with three copies of chromosome 21 instead of the usual two. Prior to or at conception, a pair of 21st chromosomes in either the sperm or the egg fails to separate.
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Which pregnant mother is at greatest risk for having a child with Down syndrome?

Women over age 35 are at higher risk for giving birth to a child with Down syndrome. People have long recognized there is a connection between maternal age and Down syndrome.
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Down Syndrome diagnosis in pregnancy - AMA President Dr Gannon on Lateline



What are signs of Down syndrome during pregnancy?

At birth, babies with Down syndrome usually have certain characteristic signs, including:
  • flat facial features.
  • small head and ears.
  • short neck.
  • bulging tongue.
  • eyes that slant upward.
  • atypically shaped ears.
  • poor muscle tone.
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Can stress during pregnancy cause Down syndrome?

Down syndrome, which arises from a chromosome defect, is likely to have a direct link with the increase in stress levels seen in couples during the time of conception, say Surekha Ramachandran, founder of Down Syndrome Federation of India, who has been studying about the same ever since her daughter was diagnosed with ...
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Can you tell if a baby has Down syndrome from an ultrasound?

An ultrasound can detect fluid at the back of a fetus's neck, which sometimes indicates Down syndrome. The ultrasound test is called measurement of nuchal translucency. During the first trimester, this combined method results in more effective or comparable detection rates than methods used during the second trimester.
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Does Down syndrome run in the family?

In almost all cases, Down's syndrome does not run in families. Your chance of having a baby with Down's syndrome increases as you get older, but anyone can have a baby with Down's syndrome.
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What are signs of Down syndrome on ultrasound?

Certain features detected during a second trimester ultrasound exam are potential markers for Down's syndrome, and they include dilated brain ventricles, absent or small nose bone, increased thickness of the back of the neck, an abnormal artery to the upper extremities, bright spots in the heart, 'bright' bowels, mild ...
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What are the 4 main causes of birth defects?

What causes birth defects?
  • Genetics. One or more genes might have a change or mutation that prevents them from working properly. ...
  • Chromosomal problems. ...
  • Exposures to medicines, chemicals, or other toxic substances. ...
  • Infections during pregnancy. ...
  • Lack of certain nutrients.
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What foods prevent chromosomal abnormalities?

Eating a healthful diet that contains foods that have folic acid, such as breakfast cereals, grain products, leafy greens, oranges and orange juice, and peanuts. Reaching or maintaining a healthy weight. Avoiding smoking and drinking alcohol.
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What vitamins prevent birth defects?

Folic Acid is An Important Vitamin

Folic acid is a vitamin found in many foods and multivitamin supplements. It's especially important for women who could become pregnant because folic acid can help prevent birth defects.
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Who is most at risk for Down syndrome?

Here's what to know about them. Maternal Age: Down syndrome can occur at any maternal age, but the possibility increases as a woman gets older. A 25-year-old woman has a one in 1,200 chance of having a baby with Down syndrome. By 35 years of age, the risk increases to one in 350—and it becomes one in 100 by age 40.
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Does father's age affect Down syndrome?

July 1, 2003 -- Older fathers may contribute just as much as older mothers to the dramatic increase in Down syndrome risk faced by babies born to older couples. A new study found that older fathers were responsible for up to 50% of the rise in Down syndrome risk when the mother was also over 40.
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What gender is Down syndrome most common?

Down syndrome appears to be more common among boys than girls, the study indicates. The condition is also seen more frequently in Hispanic children at birth, though the number of these children appears to level off with that of white children as they age. Black children appear less likely to have Down syndrome.
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Who carries the gene for Down syndrome?

People with translocation Down syndrome can inherit the condition from an unaffected parent. The parent carries a rearrangement of genetic material between chromosome 21 and another chromosome. This rearrangement is called a balanced translocation .
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Is Down syndrome inherited from the mother or father?

There is no definitive scientific research that indicates that Down syndrome is caused by environmental factors or the parents' activities before or during pregnancy. The additional partial or full copy of the 21st chromosome which causes Down syndrome can originate from either the father or the mother.
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What happens if Down syndrome test is positive?

A screen positive result means that you are in a group with an increased likelihood of having a baby with an open neural tube defect. If the result is screen positive, you will be offered an ultrasound examination after 16 weeks of pregnancy, and possibly an amniocentesis.
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How common is Down syndrome in pregnancy?

Down syndrome is the result of an extra number 21 chromosome. The extra genetic material causes the changes that characterize the condition. This condition occurs in approximately 1 in 500 births.
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How accurate is blood test for Down syndrome in pregnancy?

According to the latest research, this blood test can detect up to 98.6% of fetuses with trisomy 21. The chance of having a child with Down syndrome with a “positive” result varies widely depending on maternal age and gestational age.
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Is Down syndrome picked up at 20 week scan?

Diagnosing Down syndrome

It is necessary to look at fetal cells through a microscope to diagnose a chromosomal abnormality. Therefore, chromosomal lesions such as Down syndrome cannot be diagnosed with ultrasound. Some 40% of Down syndrome fetuses will appear normal on the 19-20 week scan.
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What is considered low risk for Down syndrome?

This means that if your screening test results show a risk of between 1 in 2 to 1 in 150 that the baby has Down's syndrome, this is classified as a higher risk result. If the results show a risk of 1 in 151 or more, this is classified as a lower risk result.
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Can anxiety cause birth defects?

9 issue of The Lancet that women who experience severe emotional stress in the first trimester of pregnancy, such as the death of a child, are more likely than women who do not experience that type of stress to have a baby with defects of a particular type, mainly heart defects or cleft lip, cleft palate, or both.
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What causes birth defects in first trimester?

These defects can be very minor or severe and typically develop in the first three months of pregnancy. About 70% of the time, the cause of the defect is not known. However, known causes of birth defects can also include genetics or exposure of the mother to harmful agents or medications.
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