What organs are affected by chemotherapy?

Some of the organs that may be affected by chemotherapy include the:
  • heart.
  • lungs.
  • liver.
  • kidneys.
  • bladder.
  • female reproductive system.
  • male reproductive system.
  • nervous system, including peripheral nerve damage.
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What organ is most affected by chemotherapy?

Excretory system (kidneys and bladder)

The kidneys work to excrete the chemotherapy drugs as they move through your body. In the process, some kidney and bladder cells can become irritated or damaged.
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Can chemotherapy affect other organs?

Chemo may have no serious long-term problems for many people. But in some cases, it can cause permanent changes or damage to the heart, lungs, nerves, kidneys, and reproductive or other organs. Certain types of chemo may also have delayed effects. For example, a second cancer may develop in the future.
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What is the most serious side effect of chemotherapy?

I answer this question for them (depends on the type of chemotherapy), but then start talking about a more serious side effect called neutropenia. It's one that they might not know to ask about. Neutropenia, pronounced noo-troh-PEE-nee-uh, is a low white blood cell count.
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Does chemo affect liver and kidneys?

Some drugs can cause changes in the way that your kidneys, liver, heart or lungs work. The changes are usually temporary and stop when your treatment ends. But some drugs might cause permanent changes. Some chemotherapy drugs, targeted cancer drugs and immunotherapies are most likely to cause these changes.
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Acute Complications of Chemotherapy (side effects, adverse effects)



Does chemo permanently damage your body?

The side effects of chemotherapy can linger for months and sometimes years. It depends on your overall health and the type of chemotherapy you receive as treatment. Some complications of chemotherapy are permanent. These can include damage to your respiratory, circulatory, sensory, excretory, and reproductive systems.
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How do you know if chemo is killing you?

Here are some signs that chemotherapy may not be working as well as expected: tumors aren't shrinking. new tumors keep forming. cancer is spreading to new areas.
...
Along the way, the timeline may have to be adjusted due to:
  1. low blood counts.
  2. adverse effects to major organs.
  3. severe side effects.
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What is the life expectancy after chemotherapy?

During the 3 decades, the proportion of survivors treated with chemotherapy alone increased from 18% in 1970-1979 to 54% in 1990-1999, and the life expectancy gap in this chemotherapy-alone group decreased from 11.0 years (95% UI, 9.0-13.1 years) to 6.0 years (95% UI, 4.5-7.6 years).
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Which is harder on the body chemo or radiation?

Since radiation therapy is focused on one area of your body, you may experience fewer side effects than with chemotherapy. However, it may still affect healthy cells in your body.
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What should you not do after chemo?

9 things to avoid during chemotherapy treatment
  • Contact with body fluids after treatment. ...
  • Overextending yourself. ...
  • Infections. ...
  • Large meals. ...
  • Raw or undercooked foods. ...
  • Hard, acidic, or spicy foods. ...
  • Frequent or heavy alcohol consumption. ...
  • Smoking.
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What are the late effects of chemotherapy?

Late effects of chemotherapy include:
  • Fatigue.
  • Difficulty with focused thinking (sometimes called chemo brain).
  • Early menopause.
  • Heart problems.
  • Reduced lung capacity.
  • Kidney and urinary problems.
  • Nerve problems such as numbness and tingling.
  • Bone and joint problems.
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Can chemotherapy cause death?

In this series, 2.3% of patients died from chemotherapy-related toxicity and 1.6% died from acute pneumonitis following thoracic radiotherapy. Unsurprisingly, advanced clinical stage of cancer and poor performance status correlated with an increased risk of a chemotherapy-related death.
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How long is someone immunocompromised after chemo?

During that time, you would be considered to be immunocompromised — not as able to fight infection. After finishing chemotherapy treatment, it can take anywhere from about 21 to 28 days for your immune system to recover.
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How long can you live after chemo stops working?

Patients who died under palliative care service had longer median survival (120 days) after last chemotherapy as compared to other patients [120 and 43 days respectively, P < 0.001, Figure 2].
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Does chemo get harder with each treatment?

The effects of chemo are cumulative. They get worse with each cycle. My doctors warned me: Each infusion will get harder. Each cycle, expect to feel weaker.
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Why do oncologists push chemo?

An oncologist may recommend chemotherapy before and/or after another treatment. For example, in a patient with breast cancer, chemotherapy may be used before surgery, to try to shrink the tumor. The same patient may benefit from chemotherapy after surgery to try to destroy remaining cancer cells.
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How sick does chemo make you?

Chemotherapy can cause fatigue, loss of appetite, nausea, bowel issues such as constipation or diarrhoea, hair loss, mouth sores, skin and nail problems. You may have trouble concentrating or remembering things. There can also be nerve and muscle effects and hearing changes. You will be at increased risk of infections.
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Is there a limit to how much chemotherapy you can have?

How long can treatment go on? This is a very good question to ask, but one that's very hard to answer. There's no way to give an exact time limit.
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Will chemo shorten my life?

During the 3 decades, the proportion of survivors treated with chemotherapy alone increased (from 18% in 1970-1979 to 54% in 1990-1999), and the life expectancy gap in this chemotherapy-alone group decreased from 11.0 years (95% UI, 9.0-13.1 years) to 6.0 years (95% UI, 4.5-7.6 years).
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What cancers have the lowest survival rate?

The cancers with the lowest five-year survival estimates are mesothelioma (7.2%), pancreatic cancer (7.3%) and brain cancer (12.8%). The highest five-year survival estimates are seen in patients with testicular cancer (97%), melanoma of skin (92.3%) and prostate cancer (88%).
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Can you live a normal life after chemo?

When treatment ends, you may expect life to return to the way it was before you were diagnosed with cancer. But it can take time to recover. You may have permanent scars on your body, or you may not be able to do some things you once did easily. Or you may even have emotional scars from going through so much.
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Can chemo speed up death?

A British inquiry into the use of chemotherapy to treat seriously ill cancer patients has found the treatment caused or hastened death in 27% of cases.
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Why would chemotherapy be stopped?

If your blood cell levels are too low, the doctors will have to put off your next treatment until the levels have recovered. This may be called a chemotherapy break. This doesn't matter too much. It shouldn't make the treatment any less effective.
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How can I protect my liver from chemo?

If you are at risk of liver damage following cancer treatment, you can help lower the risk by keeping your liver healthy.
  1. Get immunized against hepatitis A and B.
  2. Avoid alcohol or limit the amount you drink.
  3. Drink plenty of water.
  4. Eat a well-balanced diet and less fatty, salty, smoked and cured foods.
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