What medications should not be taken with omeprazole?

Cautions with other medicines
  • heart medicines, such as digoxin.
  • cilostazol, a medicine that treats peripheral arterial disease (PAD)
  • antifungal medicines, such as itraconazole, ketoconazole, posaconazole and voriconazole.
  • methotrexate, a medicine that treats psoriasis and rheumatoid arthritis.
  • HIV medicines.
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What are the dangers of taking omeprazole?

Side effects of omeprazole Brand names: Losec, Losec MUPS, Pyrocalm
  • Headaches. Make sure you rest and drink plenty of fluids, but it's best to not to drink alcohol. ...
  • Feeling sick (nausea) Try taking omeprazole with or after a meal or snack. ...
  • Being sick (vomiting) or diarrhoea. ...
  • Stomach pain. ...
  • Constipation. ...
  • Farting (flatulence)
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Does omeprazole interact with anything?

Some products that may interact with this drug include: cilostazol, clopidogrel, methotrexate (especially high-dose treatment), rifampin, St John's wort. Some products need stomach acid so that the body can absorb them properly. Omeprazole decreases stomach acid, so it may change how well these products work.
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What medication Cannot be taken with omeprazole?

Results. Omeprazole has actual adverse influences on the pharmacokinetics of medications such as diazepam, carbamazepine, clozapine, indinavir, nelfinavir, atazanavir, rilpivirine, methotrexate, tacrolimus, mycophenolate mofetil, clopidogrel, digoxin, itraconazole, posaconazole, and oral iron supplementation.
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Can you take omeprazole with blood pressure medicine?

Adding omeprazole to long-term amlodipine therapy in patients with hypertension and ARD may lead to a significantly more pronounced antihypertensive effect in patients genotyped CYP2C19 IMs.
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How and When to take Omeprazole (Prilosec / Losec) | Side Effects All Patients Need to Know



Does omeprazole affect the heart?

About 431 of these patients took PPIs, most commonly Prilosec (omeprazole), to control stomach problems from CAD medications. But, patients who took PPIs had a higher risk of heart failure and death that those who did not, about 14.65 percent versus 5.45 percent.
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Does omeprazole cause high BP?

3.1. Treatment with omeprazole causes endothelial dysfunction without significantly increasing arterial blood pressure. We found that chronic treatment with omeprazole neither increased SBP nor significantly aggravated 2K1C hypertension (Fig.
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What happens if you lay down after taking omeprazole?

glass of liquid. Do not lie down immediately after taking medicine, to make sure the pills have gone through the esophagus into the stomach. Notify your healthcare provider if you experience painful swallowing or feel that the medicine is sticking in your throat.
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What painkillers can I take with omeprazole?

Taking omeprazole with painkillers

It is safe to take painkillers such as paracetamol or ibuprofen at the same time as omeprazole. It's best to take ibuprofen with, or just after, a meal so it does not upset your stomach.
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When is the best time to take omeprazole?

You'll usually take omeprazole once a day, first thing in the morning. It will not affect your stomach, so you can take it with or without food. If you take omeprazole twice a day, take 1 dose in the morning and 1 dose in the evening. Swallow tablets and capsules whole with a drink of water or squash.
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Can omeprazole make acid reflux worse?

The proportion of reflux episodes greater than pH 4 increased from 37% to 98% (P < 0.0001). In normal subjects, omeprazole treatment does not affect the number of reflux episodes or their duration; rather it converts acid reflux to less acid reflux, thus exposing esophagus to altered gastric juice.
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What is the safest drug for acid reflux?

Proton pump inhibitors are accepted as the most effective initial and maintenance treatment for GERD. Oral pantoprazole is a safe, well tolerated and effective initial and maintenance treatment for patients with nonerosive GERD or erosive esophagitis.
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Can omeprazole cause anxiety?

Omeprazole (OM) is one of the most prescribed drugs worldwide for the treatment of hyperacidity and gastric reflux. However, concerns regarding its safety have emerged recently, and the drug is reported to enhance the risk for anxiety and cognitive deficits, particularly in elderly patients.
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How long can you safely take omeprazole?

You should not take it for more than 14 days or repeat a 14-day course more often than every 4 months unless directed by a doctor. Do not crush, break, or chew the tablet.
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Can I drink coffee after taking omeprazole?

In general, food does not affect the absorption or effectiveness of omeprazole. However, since the goal is to reduce stomach acid, it's probably not sensible to take omeprazole and then eat foods that overstimulate stomach acid secretion such as spicy foods, fatty foods, sodas, alcohol, or coffee.
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What are the long term side effects of omeprazole 40 mg?

Prilosec (omeprazole) is a proton pump inhibitor that treats severe stomach acid-related conditions like GERD. Common Prilosec side effects include headache, stomach pain and nausea. Long-term Prilosec use has been linked to kidney damage, bone fractures and other dangerous side effects.
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How long should I wait to eat after taking omeprazole?

Omeprazole tablets may be taken with food or on an empty stomach. Take omeprazole powder for oral suspension on an empty stomach at least 1 hour before a meal.
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Can I drink milk after taking omeprazole?

The milk interferes with the absorption of various antibiotics such as tetracycline's (decreasing absorption) and few quinolones, propranolol, mercaptopurine (reduce bioavailability), nonsteroidal anti-inflammatory drugs, digitalis, amiloride, omeprazole, spironolactone and ranitidine.
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Does omeprazole affect absorption of other medications?

May interact with some other medications including methotrexate and sometimes warfarin. Omeprazole can also reduce the absorption of drugs that are dependant on a certain gastric pH for their absorption. It may also interact with drugs metabolized through the cytochrome P450 pathway (particularly CYP2C19 and CYP3A4).
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What are the symptoms of too much acid in your stomach?

Some signs that you may have high stomach acid include:
  • abdominal discomfort, which may be worse on an empty stomach.
  • nausea or vomiting.
  • bloating.
  • heartburn.
  • diarrhea.
  • decreased appetite.
  • unexplained weight loss.
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Does drinking water help heartburn?

This can help prevent acid reflux symptoms. According to a 2019 case study , frequent sips of water can help clear acid from the esophagus. Beverages such as coffee, soda, and acidic juices may increase the risk or severity of reflux symptoms.
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Does milk help acid reflux?

Does milk help with heartburn? "Milk is often thought to relieve heartburn," says Gupta. "But you have to keep in mind that milk comes in different varieties — whole milk with the full amount of fat, 2% fat, and skim or nonfat milk. The fat in milk can aggravate acid reflux.
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Can omeprazole affect your cholesterol?

Answer. The full paperwork on Prilosec does list high blood pressure as possible side effect but not increase in cholesterol. You should know: The answer above provides general health information that is not intended to replace medical advice or treatment recommendations from a qualified healthcare professional.
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Does omeprazole make your hair fall out?

The medication listing compendium we use states that hair loss is not a side effect posted for Prilosec.
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Can omeprazole affect your stools?

This medication may increase your risk of severe diarrhea. This diarrhea may be caused by an infection (Clostridium difficile) in your intestines. Call your medical professional or seek medical help right away if you have watery stools, stomach pain, or fever.
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