What kind of cancer causes high protein in the blood?

Multiple Myeloma (also known as Myeloma or Plasma Cell Myeloma) is a malignancy of plasma cells, which are the white blood cells responsible for the production of antibodies (proteins). Antibodies protect humans from infections.

What cancers cause high protein in blood?

Possible Causes

Viral infections such as hepatitis B, hepatitis C or HIV/AIDS. Blood cancers such as multiple myeloma or certain types of lymphoma. Severe liver or kidney disease.

What is usually the first early symptom of multiple myeloma?

Multiple myeloma causes many symptoms, but bone pain often is the first symptom people notice. Other symptoms include: Weakness in your arms and legs and/or a sensation of numbness in your arms and legs. Multiple myeloma can affect the bones in your spine, causing them to collapse and press on your spinal cord.

What is life expectancy with multiple myeloma?

As myeloma treatments are advancing, people have more hope in managing the disease. “About 20 years ago, the life expectancy was about three years, and overall now it is at least five to six years,” says Bartlett.

What are the warning signs of myeloma?

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What is first stage myeloma?

Stage 1 (or stage I) multiple myeloma is the least advanced stage. People with stage 1 myeloma have few myeloma cells in the body. The cancer cells have not yet spread very far or caused as much damage as in other stages.

What are the red flags for multiple myeloma?

High blood levels of calcium

Extreme thirst, leading to drinking a lot. Urinating (peeing) a lot. Dehydration. Kidney problems and even kidney failure.

Where does myeloma spread to first?

At first, the cells reproduce in the bone marrow of the spine. From there, they enter the bloodstream and travel to bone marrow in other parts of the body. They collect in the bone marrow and the hard, outer part of the bones. As this progression happens, the plasma cells can cause multiple tumors.

What triggers myeloma?

What Are Its Causes? Exposure to toxic chemicals, atomic radiation, anything that interferes with the immune system, or infection with cancer-causing viruses, may potentially be linked to the developing myeloma.

What is the most frequent cause of death in a patient with multiple myeloma?

Infection is a major complication and a leading cause of death in patients with multiple myeloma (MM) [1]. The risk of infection is due to a multifactorial immunodeficiency caused by the disease itself and the treatment regimens given during the different phases of therapy [2].

Where does multiple myeloma pain start?

Multiple myeloma can cause pain in affected bones – usually the back, ribs or hips. The pain is frequently a persistent dull ache, which may be made worse by movement.

Where does your back hurt with multiple myeloma?

Bone pain is a common symptom. Myeloma cells grow in the bone marrow and cortical bone, causing local bone damage or generalized thinning of the bone, which is called osteoporosis. This makes the bone more likely to break. The back or ribs are the most common sites of bone pain, but any bone can be affected.

What are unusual symptoms of multiple myeloma?

Sometimes, multiple myeloma can damage nerves, causing a condition called peripheral neuropathy. Sometimes, the abnormal proteins produced by myeloma cells can damage nerves. This damage can lead to weakness and numbness and sometimes a “pins and needles” sensation. This is also called peripheral neuropathy.

Should I be worried about high protein in blood?

A high total protein level could indicate dehydration or a certain type of cancer, such as multiple myeloma, that causes protein to accumulate abnormally. If the result of a total protein test is abnormal, further tests will be needed to identify which proteins are too high or too low.

How fast does myeloma progress?

The risk of myeloma progressing is highest in the first 5 years after diagnosis. About 50 out of 100 people (50%) with smouldering myeloma develop symptoms and need treatment within the first 5 years. However, after 5 years the risk decreases and some people never develop symptoms or need treatment.

Can high protein in blood be cured?

There is no cure for amyloidosis. Treatment of an underlying illness - if there is one - can cause the amyloidosis to go away. Drugs and diet can help manage symptoms and help prevent the production of more of the protein.

What organ is most affected by multiple myeloma?

Multiple myeloma, also known as myeloma, is a type of bone marrow cancer. Bone marrow is the spongy tissue found at the centre of some bones. It produces the body's blood cells. Multiple myeloma affects the plasma cells (a type of blood cell) inside the bone marrow.

Who is most at risk for myeloma?

People who have been exposed to radiation or to asbestos, benzene, pesticides, and other chemicals used in rubber manufacturing may be at higher risk for developing myeloma. People often exposed to wood products, such as carpenters, furniture makers, and paper makers, are also at higher risk.

Can people with myeloma live a normal life?

Apart from ongoing monitoring, most myeloma patients are able to live fairly normal lives, with few restrictions on low-impact exercise and other activity.

How do you rule out myeloma?

Specialized tests, such as fluorescence in situ hybridization (FISH) can analyze myeloma cells to identify gene mutations. Imaging tests. Imaging tests may be recommended to detect bone problems associated with multiple myeloma. Tests may include an X-ray, MRI, CT or positron emission tomography (PET).

What bones does multiple myeloma affect first?

The bones most commonly affected are the spine, pelvis, ribs, skull, and the long bones of the arms and legs.

When should you suspect multiple myeloma?

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Low red blood cell counts, white blood cell counts, and platelet counts, which are common in multiple myeloma. High levels of calcium in your blood, called hypercalcemia. Abnormal proteins in your blood or urine.

Does multiple myeloma come on suddenly?

The bone damage associated with multiple myeloma occurs mostly in the rib cage, spine and pelvis, increasing the risk of spinal cord compression, which causes pain, numbness or weakness in the limbs and requires immediate treatment. It may come on gradually or suddenly.

How do doctors test for myeloma?

A bone marrow biopsy is usually needed to confirm multiple myeloma. A needle is used to take a small sample of bone marrow (where all the blood cells are made) from one of your bones, usually the pelvis. A small sample of bone may also be removed.

Can myeloma be cured if caught early?

While there is no cure for multiple myeloma, the cancer can be managed successfully in many patients for years. The common types of treatments used for multiple myeloma are described below. Your care plan may also include treatment for symptoms and side effects, an important part of cancer care.