What is triple maceration?

August 12, 2013 at 5:13 AM · Triple Maceration Process:- -------------------------- In this maceration process,the drug is macerated thrice by using the menstruum which is divided into three parts in such a manner that the same volume is used for each maceration.

What is multiple maceration?

Multiple maceration - a process to prepare concentrated extract. It includes 'Double maceration' and 'Triple maceration'.

What is maceration in pharmacy?

(i) Maceration. This is an extraction procedure in which coarsely powdered drug material, either leaves or stem bark or root bark, is placed inside a container; the menstruum is poured on top until completely covered the drug material. The container is then closed and kept for at least three days.

What maceration means?

1 : to cause to waste away by or as if by excessive fasting. 2 : to cause to become soft or separated into constituent elements by or as if by steeping in fluid broadly : steep, soak. intransitive verb.

Which is prepared by double or triple maceration process?

➢ Double maceration is used for concentrated infusions which contain volatile oil, e.g. Concentrated Compound Gentian Infusion. ➢ Where the marc cannot be pressed, a process of triple maceration is sometimes employed.

4..Double maceration, Triple maceration

What is double maceration process?

In double maceration process, the whole of the drug is macerated for 48 hours with the quantity of the menstruum required for first maceration. The liquid is strained and the marc is pressed. The marc is macerated again for 24 hours with the remaining menstruum required for second maceration.

What are the three main types of extraction methods?

The three most common types of extractions are: liquid/liquid, liquid/solid, and acid/base (also known as a chemically active extraction). The coffee and tea examples are both of the liquid/solid type in which a compound (caffeine) is isolated from a solid mixture by using a liquid extraction solvent (water).

What is the difference between infusion and maceration?

Maceration involves extracting flavors by crushing or muddling. Infusion is the easiest. Put ingredients in a jar and fill with alcohol. Since ethanol is a solvent, if the ingredients have any natural oils, they are quickly absorbed and the spirit takes on those flavors.

What does maceration look like?

Maceration occurs when skin is in contact with moisture for too long. Macerated skin looks lighter in color and wrinkly. It may feel soft, wet, or soggy to the touch. Skin maceration is often associated with improper wound care.

What is expressed liquid in maceration?

Maceration is an extractive technique that is conducted at room temperature. It consists of immersing a plant in a liquid (water, oil, alcohol, etc.) inside an airtight container, for a variable time based on the plant material and liquid used.

How do you reduce maceration?

To prevent maceration, it is important to change dressings frequently. Leaving dressings on for too long, especially for wounds that are producing large volumes of exudate, can lead to maceration. Heavily exudative wounds should not have dressings left on for more than one day.

What are the 2 methods of extraction?

Extraction methods include solvent extraction, distillation method, pressing and sublimation according to the extraction principle. Solvent extraction is the most widely used method.

What is the basic principle of extraction?

The principle behind solvent extraction is extremely basic. The goal is to use a liquid (solvent) to dissolve (solvate) a target molecule or group of compounds (solute) and to wash them out of the solid plant material. The solvent is then separated from the solute in order to concentrate the solute.

What are the different method of extraction?

What is Marc and Menstruum?

For example, marc could be the herbs in a soaked tea bag or those that were used to make a tincture or elixir after they have been pressed and separated from the liquid extract. Menstruum or Solvent: The liquids used to extract an herbal preparation are called the menstruum, or solvent.

What is the difference between maceration and percolation?

The main difference between maceration and percolation is that the maceration is a process of soaking something to make it softer whereas the percolation is the seepage or filtration of a liquid through a porous substance.

What is percolation method?

Percolation is an exhaustive extraction procedure, by which all of the soluble constituents are completely removed from a comminuted plant material, by extracting the crude drug by fresh solvent. In the case of repercolation, the percolate is again introduced as the solvent, thus reducing solvent consumption.

Which solvent is best for extraction?

Methanol was identified as the most effective solvent for the extraction, resulting in the highest extraction yield (33.2%) as well as the highest content of phenolic (13.36 mg GAE/g DW), flavonoid (1.92 mg QE/g DW), alkaloid (1.40 mg AE/g DW), and terpenoids (1.25%, w/w).

What chemical properties are used in extraction?

Extraction yields as well as physicochemical properties like refractive index, color perception, melting point, viscosity, iodine value, saponification value, and peroxide value are usually assessed for oils in order to evaluate their compositional quality as well as their nutritional and sensory properties.

Which law is used in solvent extraction?

THE thermodynamic law for the partition of a solute between two immiscible or partially miscible solvents is: a = K a′ where a and a′ are the activities in the two phases, and K is a constant.

Why is diethyl ether used in extraction?

Diethyl ether is a common laboratory aprotic solvent. It has limited solubility in water (6.05 g/100 ml at 25 °C) and dissolves 1.5 g/100 g (1.0 g/100 ml) water at 25 °C. This, coupled with its high volatility, makes it ideal for use as the non-polar solvent in liquid-liquid extraction.

What is efficiency of extraction?

Extraction efficiency—that is, the percentage of solute that moves from one phase to the other—is determined by the equilibrium constant for the solute's partitioning between the phases and any other side reactions that involve the solute.

What is difference between extract and tincture?

The difference between extracts and tinctures is the amount of herb infused in the alcohol or glycerin. An extract is considered 1 part herb to 1 part alcohol or glycerin. A tincture is considered 1 part herbs to 3 parts alcohol or glycerin.

What causes maceration?

Excessive exposure to moisture can cause maceration, a serious problem for your skin. Skin maceration happens when your skin is broken down by moisture on a cellular level. Once this damage occurs, your skin is much more vulnerable to other types of problems and complications.

Why is my skin white around my stitches?

Wounds need to be lightly moist to heal. Unfortunately, too much moisture and the wound can become macerated. If you spend too much time in the bathtub and your skin turns white and wrinkly, that's maceration. In an open wound, however, that can be a major problem.