What is the sister disease to MS?

Neuromyelitis optica, also called NMO or Devic's disease, is a rare yet severe demyelinating autoimmune inflammatory process affecting the central nervous system. It specifically affects the myelin, which is the insulation around the nerves.
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What diseases are linked to MS?

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  • Acute Disseminated Encephalomyelitis (ADEM) ...
  • Balo's Disease. ...
  • HTLV-I Associated Myelopathy (HAM) ...
  • Neuromyelitis Optica (NMO) ...
  • Schilder's Disease. ...
  • Transverse Myelitis.
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What is another disease similar to MS?

These include fibromyalgia and vitamin B12 deficiency, muscular dystrophy (MD), amyotrophic lateral sclerosis (ALS or Lou Gehrig's disease), migraine, hypo-thyroidism, hypertension, Beçhets, Arnold-Chiari deformity, and mitochondrial disorders, although your neurologist can usually rule them out quite easily.
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Is Devic's disease worse than MS?

With MS, changes in memory, reasoning, problem solving and depression are also common. Vision loss with MS usually affects one eye at a time, but Devic's disease/NMO may affect both eyes at the same time. Symptoms are generally more severe for the Devic's disease/NMO attack than the MS attack.
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What is the sister to MS?

Neuromyelitis Optica - A Sister to Multiple Sclerosis.
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Multiple sclerosis - causes, symptoms, diagnosis, treatment, pathology



Which is worse NMO or MS?

Symptoms of NMO are usually severe than multiple sclerosis (MS). The individual episodes in NMO are more serious compared to MS. Their cumulative effect will have debilitating, irreversible effects on nerve functions.
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How long do NMO attacks last?

There are two types of NMO: Monophasic NMO: This single acute attack of NMO lasts for about 1 month and does not recur within 3 years. It occurs very rarely. In fact, a 2020 study that followed people with NMO for a longer period of time suggests the condition might not actually exist.
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How long can you live with Devics disease?

NMO is also known as Devic's disease or neuromyelitis optica spectrum disorder (NMOSD). Patients with neuromyelitis optica (NMO) patients have a 91% to 98% five-year survival rate. Current research indicates that neuromyelitis optica (NMO) patients have a 91% to 98% five-year survival rate.
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How do you get Devic's disease?

NMO is also known as neuromyelitis optica spectrum disorder or Devic's disease. It occurs when your body's immune system reacts against its own cells in the central nervous system, mainly in the optic nerves and spinal cord, but sometimes in the brain.
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How do you test for Devic's disease?

Diagnosis and Tests

Testing for Devic's disease may include MRI (magnetic resonance imaging) scans to show inflammation of the spinal cord. MRI uses a large magnet, radio waves and a computer to produce images. In a person with Devic's disease, the MRI scan may show inflammation in a long segment of the spinal cord.
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What autoimmune disease is similar to MS?

Sjogren's syndrome is an autoimmune disease that can mimic some of the symptoms of MS such as fatigue and joint pain.
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Is lupus worse than MS?

Yet there are differences as well. In general, lupus does more generalized damage to your body than MS, which primarily damages the nervous system.
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Can Sjogren's mimic MS?

Abstract. Background: Primary Sjögren's syndrome (SS) with central nervous system involvement and antiphospholipid syndrome have been reported to mimic multiple sclerosis (MS). SS has also been found in patients diagnosed with definite MS.
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Is MS inherited from mother or father?

MS is not directly inherited from parent to child. There's no single gene that causes it. Over 200 genes might affect your chances of getting MS.
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Do MS and fibromyalgia have similar symptoms?

Fatigue, or feeling tired all the time, is a common symptom of MS and fibromyalgia. Other similarities include: Age.
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Can you have MS and other autoimmune diseases?

Multiple sclerosis (MS) is thought by many medical researchers to be an autoimmune disease, which is when the body's immune system turns against its own tissues. There are a number of diseases that fall into this category, including lupus, rheumatoid arthritis, psoriasis, and Crohn's disease.
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Is NMO disease fatal?

Some people develop life threatening complications from NMO. One small study found that about 1 in 5 people with NMO develop breathing difficulties. Those breathing problems may require treatment with a ventilator. Fatal respiratory failure sometimes occurs.
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How can you tell the difference between MS and NMO?

In MS, individual episodes are usually mild; their cumulative effect over time may or not not cause progressive disability. In NMO, the opposite is true and therefore early diagnosis is critical; acute episodes are usually severe and – if untreated – can have devastating, irreversible effects on function.
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What are symptoms of NMO?

Symptoms of NMO
  • eye pain.
  • loss of vision.
  • colours appearing faded or less vivid.
  • weakness in the arms and legs.
  • pain in the arms or legs – described as sharp, burning, shooting or numbing.
  • increased sensitivity to cold and heat.
  • tight and painful muscle spasms in the arms and legs.
  • vomiting.
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Is there surgery for transverse myelitis?

To make matters worse, there's no cure for TM, no surgery that can fix it. At least that's what she had read. But then she learned that neurosurgeon Allan Belzberg had performed a novel nerve-repairing surgery on two other pediatric patients with transverse myelitis at Hopkins Children's.
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Is Devic's disease an autoimmune disease?

What is neuromyelitis optica? Neuromyelitis optica, also called NMO or Devic's disease, is a rare yet severe demyelinating autoimmune inflammatory process affecting the central nervous system. It specifically affects the myelin, which is the insulation around the nerves.
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What is the prognosis for transverse myelitis?

Prognosis. Although most people with transverse myelitis have at least partial recovery, it may take a year or more. Most recovery occurs within the first three months after the episode and strongly depends on the cause of transverse myelitis.
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What is the best treatment for NMO?

The standard of care for an initial attack of NMO includes the following: Intravenous (into the vein) high-dose corticosteroids (methylprednisolone)
...
Other drugs used off-label to prevent attacks include:
  • Rituxan (rituximab)
  • CellCept (mycophenolate mofetil)
  • Imuran, Azasan (azathioprine)
  • Prednisone.
  • Methotrexate.
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Is NMO painful?

Terrible, agonizing, wretched, sickening and unbearable—these are words frequently used by patients with neuromyelitis optica (NMO) to describe a very common symptom of their disease: pain. More than 80% of patients with NMO experience pain from this condition, which severely affects their quality of life.
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How do you test for NMO?

Your doctor might be able to detect lesions or damaged areas in your brain, optic nerves or spinal cord. Blood tests. Your doctor might test your blood for the autoantibody NMO -IgG, which helps doctors distinguish NMO from MS and other neurological conditions. This test helps doctors make an early diagnosis of NMO .
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