What is the safest diabetes 2 medication?

Official answer. Most experts consider metformin to be the safest medicine for type 2 diabetes because it has been used for many decades, is effective, affordable, and safe. Metformin is recommended as a first-line treatment for type 2 diabetes by the American Diabetes Association (ADA).
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What is the best type 2 diabetes medication with the least side effects?

Metformin is a tried and tested medicine that has been used for many decades to treat type 2 diabetes, and is recommended by most experts as first-line therapy. It is affordable, safe, effective, and well tolerated by most people.
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Is there a better drug for type 2 diabetes than metformin?

Insulin remains the most effective therapy to lower glucose, particularly in comparison to most oral medicines for type 2 (including metformin).
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What is the number one drug for type 2 diabetes?

Metformin (Fortamet, Glumetza, others) is generally the first medication prescribed for type 2 diabetes. It works primarily by lowering glucose production in the liver and improving your body's sensitivity to insulin so that your body uses insulin more effectively.
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What are the top 5 medications for type 2 diabetes?

  • Insulin (long- and rapid-acting) ...
  • Metformin (biguanide class) ...
  • Glipizide (sulfonylurea class) ...
  • Glimepiride (sulfonylurea class) ...
  • Invokana (sodium glucose cotransporter 2 inhibitor class) ...
  • Jardiance (SGLT2 class)​​​​​​​
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Type 2 diabetes: Which drug is best?



What can I take instead of metformin?

Alternative options
  • Prandin (repaglinide) ...
  • Canagliflozin (Invokana) ...
  • Dapagliflozin (Farxiga) ...
  • Empagliflozin (Jardiance) ...
  • Actos (pioglitazone) ...
  • Herbal options.
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What medication is replacing metformin?

Other alternatives to metformin
  • Avandia (rosiglitazone)
  • Nesina (alogliptin)
  • Tanzeum (albiglutide)
  • Jardiance (empagliflozin)
  • Invokana (canagliflozin)
  • Farxiga (dapagliflozin)
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What is the newest treatment for type 2 diabetes?

In May 2022, the FDA approved Lilly's new medication Mounjaro (also known as tirzepatide) for type 2 diabetes management, in addition to diet and exercise. This first-in-class medication has been shown to improve glucose levels and also dramatically improve weight in clinical trials.
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What is the new pill for diabetes?

How does this new diabetes medication work? Teplizumab is a monoclonal antibody that modifies T cells in a way that prolongs the pancreas' ability to create insulin. The drug is specific to a molecule called CD3, which is the “cognate” component of the T cell, Dr. Herold explains.
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What is the least harmful diabetes medication?

Official answer. Most experts consider metformin to be the safest medicine for type 2 diabetes because it has been used for many decades, is effective, affordable, and safe. Metformin is recommended as a first-line treatment for type 2 diabetes by the American Diabetes Association (ADA).
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At what A1C level should you start metformin?

Recent guidelines recommend considering use of metformin in patients with prediabetes (fasting plasma glucose 100-125 mg/dL, 2-hr post-load glucose 140-199 mg/dL, or A1C 5.7-6.4%), especially in those who are <60 years old, have a BMI >35 kg/m2, or have a history of gestational diabetes.
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What are the dangers of taking metformin?

Taking metformin can cause vitamin B12 deficiency.
...
Vitamin B12 deficiency
  • feel very tired.
  • have muscle weakness.
  • have a sore, red tongue.
  • have mouth ulcers.
  • have problems with your vision.
  • have pale or yellow skin (this may be less obvious on brown or black skin.
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What is the humble pill for diabetes?

For decades we've known that metformin does more than just help lower blood sugar in people with diabetes. It also offers them cardiovascular benefits, including lower rates of death due to cardiovascular disease. And it sometimes helps people with diabetes lose excess weight.
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Is there a pill for diabetes instead of insulin?

Metformin(Glucophage) is usually the first pill that doctors prescribe for type 2 diabetes. (You can take it as a liquid, too.) Metformin lowers the amount of blood sugar that your liver makes and helps your body use insulin more effectively.
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What is the new miracle weight loss drug?

In June 2021, the FDA approved semaglutide (Wegovy), a once-weekly injection, for chronic weight management in adults when used in combination with a healthy diet and exercise. The medication had made headlines before its approval when the manufacturer reported 15% to 18% weight loss findings during clinical trials.
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What level of A1C requires insulin?

Insulin therapy will often need to be started if the initial fasting plasma glucose is greater than 250 or the HbA1c is greater than 10%.
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What is the new treatment for type 2 diabetes 2022?

Mounjaro (Tirzepatide) In May 2022, the FDA approved the novel type 2 diabetes injectable medication called Mounjaro (tirzepatide). 5 Mounjaro is the first and only FDA-approved dual GIP and GLP-1 agonist medication for type 2 diabetes.
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What is the fastest way to reverse type 2 diabetes?

Making positive lifestyle changes such as eating a well-balanced diet, exercising regularly and getting down to a healthy weight (and maintaining it) are the key to possibly reversing or managing type 2 diabetes.
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Can diabetes Type 2 be cured without medication?

Although there's no cure for type 2 diabetes, studies show it's possible for some people to reverse it. Through diet changes and weight loss, you may be able to reach and hold normal blood sugar levels without medication. This doesn't mean you're completely cured. Type 2 diabetes is an ongoing disease.
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What happens to your body when you stop taking metformin?

If you stop taking metformin abruptly, your health may suffer. You may experience side effects such as higher blood sugars, an increased A1c, and even weight gain. Over time, higher blood sugar levels can lead to diabetes complications, including: Retinopathy and blindness.
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What is a natural form of metformin?

Metformin is a synthetic derivative of galegine and/or guanidine, natural products found in the herbal medicine Galega officinalis that was used in medieval Europe.
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Does metformin make you look younger?

Metformin is a commonly used drug for treating patients with Type 2 diabetes. Extensive research has shown that metformin can also be used as an anti-aging therapy. For this reason, many people without diabetes, including Silicon Valley techies, take the inexpensive drug in the hopes it will keep them healthy longer.
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