What is the most tolerated antidepressant?

Escitalopram and sertraline stand out.
Bupropion, citalopram, escitalopram, and sertraline were better tolerated than the other antidepressants. Escitalopram and sertraline were found to have the best combination of efficacy and acceptability.
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What is the most effective antidepressant with the least side effects?

Selective serotonin reuptake inhibitors (SSRIs).

These medications generally cause fewer bothersome side effects and are less likely to cause problems at higher therapeutic doses than other types of antidepressants are.
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What is the most tolerable antidepressant?

Overall, citalopram appears to be the best-tolerated SSRI, followed by fluoxetine, sertraline, paroxetine, and fluvoxamine. The latter 2 drugs are associated with the most side effects and the highest discontinuation rates because of side effects in clinical trials.
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What is the most mild antidepressant?

Which antidepressants have the mildest side effects? In general, SSRIs are considered the most well-tolerated antidepressants, per the Mayo Clinic; they typically have fewer side effects than other types and can be safely used at higher doses.
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What is the best antidepressant for anxiety with the least side effects?

As of this writing, some of the anxiety medications with the fewest reported side effects and least risk of side effects include:
  • Most Benzodiazepines (Xanax, Valium)
  • Bupropion (Wellbutrin)
  • Citalopram (Celexa - SSRI)
  • Paroxetine (Paxil - SSRI)
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SSRIs and New Antidepressants



What is the drug of choice for anxiety?

Benzodiazepines (also known as tranquilizers) are the most widely prescribed type of medication for anxiety. Drugs such as Xanax (alprazolam), Klonopin (clonazepam), Valium (diazepam), and Ativan (lorazepam) work quickly, typically bringing relief within 30 minutes to an hour.
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Is there a medication that treats both depression and anxiety?

Selective serotonin reuptake inhibitors (SSRIs) are a class of medications that have a broad therapeutic range. They can be used to treat anxiety disorders, depression, or, in some cases, both at the same time.
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What is the best antidepressant 2020?

Based on their analysis, the review authors concluded sertraline and escitalopram were the best antidepressants overall in terms of efficacy and patient acceptability. Sertraline was found to be more effective than duloxetine by 30%, fluvoxamine (27%), fluoxetine (25%), paroxetine (25%), and reboxetine (85%).
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What are the top 3 antidepressants?

Selective serotonin reuptake inhibitors (SSRIs) are the most prescribed type of antidepressant and include: Fluoxetine. Citalopram. Sertraline.
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Is there a mild antidepressant?

Bupropion (Aplenzin, Wellbutrin) is a unique antidepressant that is thought to affect the brain chemicals norepinephrine and dopamine. Side effects are usually mild, including upset stomach, headache, insomnia, and anxiety.
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What is the best antidepressant for anxiety and panic attacks?

The selective serotonin reuptake inhibitors (SSRIs) are the most commonly prescribed drugs for panic today and offer fewer side effects than the tricyclic antidepressants. These include fluoxetine (Prozac), fluvoxamine (Luvox), sertraline (Zoloft), paroxetine (Paxil), citalopram (Celexa) and escitalopram (Lexapro).
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Which is better Lexapro or Zoloft?

A 2014 study published in International Clinical Psychopharmacology suggested that Lexapro may be more effective and better tolerated than Zoloft or Paxil. Lexapro has different binding site interactions which may lead to better efficacy and tolerability.
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What is better Prozac or Zoloft?

Which is More Effective? Both Prozac and Zoloft are considered powerful mental health medications, comparably effective at treating depression and reducing anxiety for the patients who take them. A few clinical trials suggest that Zoloft may have less serious side effects than Prozac.
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Is Wellbutrin or Lexapro better?

Wellbutrin vs Lexapro: Which is better? There is no clear-cut answer in choosing between Lexapro and Wellbutrin. That is because each person is different, with potentially different responses and sensitivities to a medication. Both drugs have been effective in depressed patients.
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What is the best antidepressant for energy and motivation?

Prozac/Fluoxetine

It gives people more energy than other antidepressants which may not work well for someone with insomnia as well as depression. That being said, for those with low energy, it can be helpful. Fluoxetine treats many mental health issues which includes depression, OCD, and panic disorders.
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Which antidepressant medication has the least side effects in the elderly?

SSRIs considered to have the best safety profile in the elderly are citalopram, escitalopram, and sertraline.
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Is Wellbutrin better than Zoloft?

Is Wellbutrin or Zoloft better? Multiple studies have shown Wellbutrin and Zoloft to be relatively comparable in achieving remission of depression symptoms. Wellbutrin may be favored over Zoloft due to the fact that its side effect profile is less severe.
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Is Prozac better than Lexapro?

When considering Prozac vs Lexapro, both medications are approved to treat major depressive disorder (MDD). A 2014 study found that Lexapro was more effective than Prozac in treating severe periods of depression.
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What is the newest drug for depression?

On March 5, 2019, the Food and Drug Administration (FDA) approved the first new medication for major depression in decades. The drug is a nasal spray called esketamine, derived from ketamine—an anesthetic that has made waves for its surprising antidepressant effect.
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What is the best meds for anxiety and depression?

When treating anxiety disorders, antidepressants, particularly the SSRIs and some SNRIs (serotonin-norepinephrine reuptake inhibitors), have been shown to be effective. Other anti-anxiety drugs include the benzodiazepines, such as as alprazolam (Xanax), diazepam (Valium), buspirone (Buspar), and lorazepam (Ativan).
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What is the best antidepressant for sensitive stomach?

Certain antidepressants can help regulate abnormal bowel functions, as well as other IBS symptoms. Tricyclic antidepressants (TCAs) help with diarrhea, serotonin reuptake inhibitors (SSRIs) help with constipation, and serotonin-norepinephrine reuptake inhibitors (SNRIs) can help with visceral pain.
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What is the 3 3 3 rule for anxiety?

Follow the 3-3-3 rule.

Look around you and name three things you see. Then, name three sounds you hear. Finally, move three parts of your body — your ankle, fingers, or arm.
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Why do you feel worse when starting antidepressants?

When you start an antidepressant medicine, you may feel worse before you feel better. This is because the side effects often happen before your symptoms improve. Remember: Over time, many of the side effects of the medicine go down and the benefits increase.
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What are the top 5 medications for anxiety?

SSRIs and SNRIs are often the first-line treatment for anxiety. Common SSRI brands are Celexa, Lexapro, Luvox, Paxil, and Zoloft, and common SNRI brands are Pristiq, Cymbalta, and Effexor XR. Pros: They are effective for a lot of people and they have a solid safety profile.
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