What is the most serious side effect of antipsychotics?

Taking antipsychotics can increase your risk of developing metabolic syndrome. If you experiencing metabolic syndrome, this means you are at higher risk of developing: diabetes. stroke.
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What are the major side effects of antipsychotic medications?

Side effects of antipsychotic medications
  • dry mouth.
  • dizziness.
  • weight gain that can lead to diabetes.
  • blurred vision.
  • movement effects (for example, tremor, stiffness, agitation)
  • sedation (for example causing sleepiness or low energy)
  • loss of menstrual periods in women.
  • fluid retention.
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What is the most serious consequence related to antipsychotic medications?

Severe constipation leading to serious consequences and even death can occur with certain antipsychotics.
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What is a serious side effect of older antipsychotics?

Side effects of particular concern in the elderly include anticholinergic reactions, parkinsonian events, tardive dyskinesia, orthostatic hypotension, cardiac conduction disturbances, reduced bone mineral density, sedation, and cognitive slowing.
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Do typical antipsychotics have serious side effects?

First-generation antipsychotics (FGAs), also known as neuroleptics, conventional or typical antipsychotics, have significant potential to cause extrapyramidal symptoms and tardive dyskinesia. This propensity to cause movement disorders is the primary difference between FGAs and second-generation antipsychotics (SGAs).
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Side effects of antipsychotics to remember in easy way



What are some of the most common side effect with the new atypical antipsychotics?

Common side effects of atypical antipsychotics include: Decreased sex drive. Weight gain. Diabetes.
...
Less common side effects include:
  • Involuntary body movements or facial tics (tardive dyskinesia and other movement disorders)
  • Suicidal thoughts.
  • Heart attack.
  • Heart inflammation.
  • Cataracts.
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What is an adverse outcome associated with atypical antipsychotics?

Adverse effects such as weight gain, hyperglycemia, hyper- or dyslipidemia, and hyperprolactinemia are all fairly common occurrences with these agents. Other serious adverse effects, including neuroleptic malignant syndrome (NMS) or pulmonary embolism, may also occur.
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What is the most common neurological side effect of antipsychotic medication?

The specific neurologic side effects of the antipsychotic agents include acute dystonias, parkinsonism, motor restlessness, and late choretoathetosis.
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Why do antipsychotics have a black box warning?

Atypical antipsychotics carry a black-box warning for increased risk of death and cerebrovascular events in dementia, although typical antipsychotics appear no safer.
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Can antipsychotics cause psychosis?

Tardive psychosis is a term used to describe new psychotic symptoms that begin after you have been taking antipsychotics for a while. Some scientists believe that these symptoms may be caused by your medication, not your original illness returning.
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What happens if you take too many antipsychotics?

The most common cardiovascular effects that occur after atypical antipsychotic overdose are tachycardia, mild hypotension, and prolongation of the QTc interval. Other clinical syndromes in overdose include neuroleptic malignant syndrome (NMS) and antimuscarinic delirium. Seizures may be observed.
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Can antipsychotics cause long term damage?

Many antipsychotics increase risk for metabolic syndrome and thus the risk of heart disease, diabetes, and stroke (7), which are among the common causes of premature mortality in schizophrenia (8).
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Can antipsychotics cause brain damage?

But according to a new study, long-term use of these drugs may also negatively impact brain structure. Share on Pinterest Researchers say long-term use of antipsychotic medications – particularly first-generation antipsychotics – may lead to gray matter loss in the brain.
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Which side effect of antipsychotic medication is generally Nonreversible?

Tardive dyskinesia is a serious adverse effect, characterised by repetitive, involuntary, painless movements. Features of tardive dyskinesia typically appear after months or years of antipsychotic use. Importantly, this condition is often non-reversible and difficult to treat.
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Which side effect of antipsychotic medication therapy is generally not reversible?

These first-generation antipsychotics have frequent and potentially significant neurological side effects, including the possibility of developing a movement disorder (tardive dyskinesia) that may or may not be reversible.
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Which adverse side effect would the nurse monitor for in an older patient receiving antipsychotic drug therapy?

Anticholinergic: Anticholinergic effects such as constipation, dry mouth, blurred vision, and urinary retention are particularly problematic in the elderly and may contribute to delirium. They are most common with low-potency traditional antipsychotic agents (e.g., chlorpromazine) and clozapine.
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Why are antipsychotics not recommended?

In particular, antipsychotic drugs have been linked to an increased risk of falls, diabetes and heart disease. Older adults are also more likely to be prescribed multiple medications, increasing the likelihood of negative drug interactions.
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Can antipsychotics cause dementia?

A 2008 study found that antipsychotic use causes at least a threefold increase in the risk of “serious events” in seniors with dementia within 30 days of starting the medication. The study defined serious event as a hospital admission or death.
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How does Seroquel cause death?

The main clinical findings in quetiapine overdose—resulting from α-adrenergic and histamine receptor blockade—are hypotension, tachycardia, and somnolence. Potentially life-threatening consequences from overdose include QT prolongation and respiratory depression.
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What are the 4 extrapyramidal symptoms?

Extrapyramidal side effects are a group of symptoms that can occur in people taking antipsychotic medications. 1 Symptoms of extrapyramidal effects include an inability to sit still, involuntary muscle contraction, tremors, stiff muscles, and involuntary facial movements.
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What is extrapyramidal effect?

The term "extrapyramidal effects" describes involuntary movements that you cannot control. These side effects are most common when taking antipsychotic medications? When you experience extrapyramidal effects, movements that were once voluntary happen without your control.
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What is the most powerful antipsychotic medication?

Clozapine, which has the strongest antipsychotic effect, can cause neutropenia. A problem in the treatment of schizophrenia is poor patient compliance leading to the recurrence of psychotic symptoms.
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How do antipsychotics affect the heart?

Epidemiological studies provide evidence that antipsychotics increase the risk of sudden cardiac death. Specifically, certain antipsychotics can induce prolongation of the QT interval, that can potentate a lethal ventricular arrhythmia.
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What are the common side effects of second generation antipsychotics?

Second-generation antipsychotics are more likely to cause metabolic side effects, such as: weight gain. high cholesterol. high blood pressure.
...
Side effects
  • tremors.
  • rigidity.
  • shuffling gait.
  • reduced facial expressions.
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Which medication is associated with the highest risk of tardive dyskinesia?

Medicines that most commonly cause this disorder are older antipsychotics, including: Chlorpromazine. Fluphenazine. Haloperidol.
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