What is the first stage of MS?

Clinically isolated syndrome describes a person's first episode of neurological symptoms caused by damaged myelin in the CNS. CIS is often referred to as the first stage of MS, even though it doesn't meet the MS criterion for dissemination in time (MS damage that occurs on different dates).
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How does MS usually begin?

Numbness or weakness in one or more limbs that typically occurs on one side of your body at a time. Tingling. Electric-shock sensations that occur with certain neck movements, especially bending the neck forward (Lhermitte sign) Lack of coordination.
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What does MS feel like in the beginning?

Numbness of the face, body, or extremities (arms and legs) is often the first symptom experienced by those eventually diagnosed as having MS.
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What are Stage 2 MS symptoms?

Symptoms
  • Fatigue.
  • Numbness or tingling.
  • Vision problems, such as double vision.
  • Spasticity or stiffness of the muscles.
  • Bowel and bladder problems, such as urgent need to urinate.
  • Problems with cognition, such as learning and memory or information processing.
  • Difficulty with walking and coordination.
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When should I be worried if I have MS?

That said, certain symptoms should prompt you to seek help. If you're experiencing blurred vision, numbness, weakness or dizziness at the same time and for more than a day, those symptoms could be potential early signs of MS. It's important not to let too much time slip by before seeing a doctor.
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Visualizing MS Progression



How can I test myself for MS?

Some of the most common signs of MS are:
  1. numbness, pain, or tingling.
  2. vision issues such as blurred vision, trouble seeing, or floaters.
  3. weakness.
  4. issues with walking or balance.
  5. bladder or bowel incontinence.
  6. unexplained sexual dysfunction.
  7. mood changes.
  8. brain fog.
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What part of the body does MS affect first?

Vision problems

In around 1 in 4 cases of MS, the first noticeable symptom is a problem with one of your eyes (optic neuritis). You may experience: some temporary loss of vision in the affected eye, usually lasting for days to weeks.
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How did you know you had MS?

Here's where MS (typically) starts

You may experience eye pain, blurred vision and headache. It often occurs on one side and can eventually lead to partial or total vision loss. Spinal cord inflammation, or what's called partial transverse myelitis, is the second most common symptom Shoemaker typically sees.
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Where does MS start in the body?

In people with MS, the immune system attacks cells in the myelin, the protective sheath that surrounds nerves in the brain and spinal cord. Damage to the myelin sheath interrupts nerve signals from your brain to other parts of your body. The damage can lead to symptoms affecting your brain, spinal cord and eyes.
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How is MS first diagnosed?

Neurological examination

Your neurologist will look for abnormalities, changes or weakness in your vision, eye movements, hand or leg strength, balance and co-ordination, speech and reflexes. These may show whether your nerves are damaged in a way that might suggest MS.
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When does MS start to show?

MS can appear at any age but most commonly manifests between the ages of 20 and 40. It affects women two to three times as often as men. Almost one million people in the United States have MS, making it one of the most common causes of neurological disability among young adults in North America.
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How long can you have MS Before you know it?

MS is usually diagnosed between the ages of 20 and 50, but it can go undetected for years. In fact, a 2021 study suggested that many people with MS experience disease symptoms several years before being officially diagnosed with the disease.
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Can you live with mild MS?

You may have to adapt your daily life if you're diagnosed with multiple sclerosis (MS), but with the right care and support many people can lead long, active and healthy lives.
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Can MS be very mild?

The term benign MS is sometimes used to describe a version of relapsing remitting MS with very mild or no attacks separated by long periods with no symptoms. 'Benign' means 'something doesn't cause any harm'.
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Can brain MRI detect MS?

Magnetic resonance imaging has become the single most useful test for the diagnosis of MS; MRI is sensitive to brain changes which are seen in MS. Classically, the MRI shows lesions in the white matter deep in the brain near the fluid spaces of the brain (the ventricles).
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What happens if I think I have MS?

Getting medical advice

Let the GP know about the specific pattern of symptoms you're experiencing. If they think you could have MS, you'll be referred to a specialist in conditions of the nervous system (a neurologist), who may suggest tests such as an MRI scan to check for features of MS.
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Can you feel normal with MS?

Some people with MS live symptom-free for long periods of time. Others with severe MS symptoms may need special accommodations just to go out to a restaurant, especially if they have physical limitations.
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Who gets multiple sclerosis?

Most people are diagnosed between the ages of 20 and 50, although MS can occur in young children and older adults. Where is MS most commonly found? In general, MS is more common in areas farthest from the equator.
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Where do you feel pain from MS?

Tightness or stiffness of the muscles, called spasticity, is caused directly by MS. Spasticity, will alter walking and cause pulling on the joints. This can result in pain typically in the ankles, knees, hips and back.
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What pain do you feel with MS?

MS can damage the nerves that affect your muscles. This can cause acute or paroxysmal pain in the form of spasms. Your arms and legs might shoot out uncontrollably and might have pain like cramping or pulling. Nerve pain can also be chronic in the form of painful or unusual sensations on your skin.
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Can you see MS in a blood test?

While there is no definitive blood test for MS, blood tests can rule out other conditions that cause symptoms similar to those of MS, including lupus erythematosis, Sjogren's, vitamin and mineral deficiencies, some infections, and rare hereditary diseases.
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What diseases are similar to MS?

Conditions That Can Seem Like MS
  • Epstein-Barr Virus.
  • Vitamin B12 Deficiency.
  • Diabetes.
  • Nerve Damage.
  • Eye Problems.
  • Stroke.
  • Lupus and Other Autoimmune Diseases.
  • Parkinson's Disease.
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How do you know if i dont have MS?

a full neurological examination. MRI scans of the brain, spine or both to look for MS plaques. a spinal tap to look for signs of inflammation and certain immune proteins that are often present in people with MS. blood tests to rule out other disorders.
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