What is the best treatment for CIN 2?

laser or loop electrosurgical excision procedure (leeP) are the preferred treatment methods for recurrent CIN 2 and CIN 3 (sor: B, based on clinical trials without randomization).

Will CIN 2 Go Away?

CIN 2 lesions often clear up on their own, but can also progress to CIN 3 lesions. CIN 3 is the most severe. It's a very slow-growing disease, though: fewer than half of CIN 3 lesions will have become cancer within 30 years.

Does CIN 2 always need treatment?

Right now, CIN2 is typically treated. But some studies have suggested that CIN2 lesions often regress completely without treatment and should therefore be simply monitored instead.

How long does it take for CIN 2 to go away?

In a meta-analysis of 36 studies (both randomized trials and observational studies) including 3160 patients with CIN 2, at 24 months, lesions regressed in 50 percent of patients, persisted in 32 percent, and progressed to CIN 3+ in 18 percent [14].

How long does it take for CIN 2 to develop into cancer?

However, it is estimated that 5% of CIN 2 and 12% of CIN 3 cases will progress to invasive cancer if untreated. In general, it takes 10 to 20 years for CIN to progress to cancer, allowing a significant time period for detection and treatment. Progression from CIN to cancer requires persistent HPV infection.

What is CIN

Should I be worried about CIN 2?

CIN 2 means two-thirds of the thickness of the cervical surface layer is affected by abnormal cells. There is a higher risk the abnormal cells will develop into cervical cancer. You may be offered treatment to stop this happening, or another colposcopy.

What is CIN 2 and how should it be treated?

CIN 2 is not cancer, but may become cancer and spread to nearby normal tissue if not treated. Treatment for CIN 2 may include cryotherapy, laser therapy, loop electrosurgical procedure (LEEP), or cone biopsy to remove or destroy the abnormal tissue. CIN 2 is sometimes called high-grade or moderate dysplasia.

Does CIN 2 come back?

Women treated for CIN2 or CIN3 retain an elevated risk of recurrence or even invasive cancer for years following treatment (2, 3). Thus, heightened surveillance has been the rule, with uncertainty as to whether (and when) a return to normal screening intervals can be safely permitted.

How long does it take for CIN 2 to regress?

Conclusion: CIN2 lesions regress without treatment in one year, although an ablative procedure is more effective.

What type of HPV causes CIN 2?

Results: HPV was detected in 92.9% of women with CIN 2-3 and high-risk HPV (HR-HPV) was detected in 85.8% of them. In women with cervical cancer, HPV was positive in 96.5%, HR-HPV detected in 93%.

Does CIN 2 mean I have HPV?

High grade squamous intraepithelial lesion (HSIL) encompasses the entities previously termed cervical intraepithelial neoplasia (CIN)2, CIN3, moderate and severe dysplasia and carcinoma in situ. HSIL is a squamous cell abnormality associated with human papillomavirus (HPV).

Is CIN 2 precancerous?

CIN – The outer surface of the cervix is composed of cells called squamous cells. A precancerous lesion affecting these cells is called CIN. These changes are categorized as being mild (CIN 1) or moderate to severe (CIN 2 or 3).

Should I get a hysterectomy if I have precancerous cells?

If the precancerous disease is more extensive or involves adenocarcinoma in situ (AIS), and the woman has completed childbearing, a total hysterectomy may be recommended. 1 During a total hysterectomy, the entire uterus (including the cervix) is removed.

Why do I need a second LEEP procedure?

In some instances, you may need a repeat procedure to remove all the cells completely. You may also need an additional LEEP if abnormal cells return. You're at a greater risk of recurrence if you're infected with a high-risk strain of the human papillomavirus, or HPV.

What is CIN 2 colposcopy?

Cervical intraepithelial neoplasia (CIN) is classified on a scale from one to three. CIN 1: Refers to abnormal cells affecting about one-third of the thickness of the epithelium. CIN 2: Refers to abnormal cells affecting about one-third to two-thirds of the epithelium.

Will a hysterectomy cure HPV?

A hysterectomy will not cure the HPV which has caused the CIN, as there is no cure for HPV, but the CIN cannot have spread anywhere else in your body and will only be in your cervix area-it doesn't travel through the bloodstream, and remains where the HPV infection is.

What happens if CIN 2 is left untreated?

High-Grade Abnormalities CIN-2 & CIN-3

These cells are more likely to become cancerous and invade deeper layers of the cervix if left untreated. If high-grade abnormalities are detected on a Pap smear, the woman is advised to have a colposcopy and biopsy.

Is CGIN worse than CIN?

CGIN is usually classified as low grade (mild) or high grade (severe). High grade CGIN is the equivalent of CIN3. CGIN can be multi-focal – this means that more than one area is affected at one time, with normal tissue lying between them.

How long before HPV causes cell changes?

The time from getting HPV to developing warts, cervical cell changes or cervical cancer varies. Although most people clear HPV within 2 years, we know that HPV can stay in the body for a long time before causing any problems. Cervical screening (a smear test) can help detect the virus and any cell changes early.

How many times can you have LLETZ treatment?

How many times can you have the LLETZ procedure, can you have LLETZ twice? Mr John Butler explains that most women will only need one LLETZ procedure. However, if abnormal cells come back, you may require further procedures, and this is perfectly safe and acceptable.

How can I help my cervix heal?

Folate (vitamin B₉) and vitamin B₁₂ both play a crucial role in supporting cervical health. Studies show that folate and Vitamin B₁₂ may help support healthy cervical cells due to their role in DNA repair and synthesis. Include leafy greens, Brussels sprouts, broccoli, and peanuts for a healthy dose of folate.

Can CIN 2 come back after LEEP?

About 23% of patients develop CIN2+ after LEEP treatment due to residual or recurrent lesions. The majority of patients with HPV infection were HPV negative before treatment, but 16,4% were still HPV 16 positive after treatment, indicating that conization do not necessarily clear HPV infection rapidly.

How can I get rid of cervical dysplasia naturally?

Can precancerous cells come back after LEEP?

LEEP works very well to treat abnormal cell changes on the cervix. If all of the abnormal tissue is removed, you won't need more surgery. In some studies, doctors were able to remove all the abnormal cells in almost every case. But abnormal cells may come back in the future.

How successful is LLETZ treatment?

The benefit of LLETZ is that it can stop cell changes potentially developing into cervical cancer. It is successful in over 9 in 10 (over 90%) of cases, meaning no further treatment is needed.