What is the best form of B12 to take?

For prevention and treatment of vitamin B12 deficiency, cyanocobalamin in chewable, sublingual, or liquid forms (rather than in a multivitamin) is best under most circumstances.
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Which form of B12 is best absorbed?

Methylcobalamin. Methylcobalamin is the most bio-available type of Vitamin B12 which means the body absorbs it more easily.
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What is the most effective B12?

Research has shown that methylcobalamin is more efficiently used and retained in the body than the cyanocobalamin form,” Gray says. ✔️ Read the label. The form of B12 should be clearly listed.
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What is the safest form of B12?

Answer: The most common form of vitamin B-12 (cobalamin) in supplements is cyanocobalamin and although this form includes a cyanide molecule, it is very safe.
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Is sublingual B12 better than oral?

There is a variety of vitamin B12 supplements available. Although there are claims that certain forms—like sublingual tablets or liquids placed under the tongue to be absorbed through the tissues of the mouth—have better absorption than traditional tablets, studies have not shown an important difference.
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The Best Type of Vitamin B12: Cyanocobalamin or Methylcobalamin?



Which is better cyanocobalamin or hydroxocobalamin?

The BNF states that hydroxocobalamin has completely replaced cyanocobalamin as the first choice for replacement therapy. It is certainly more convenient for the majority of patients who require lifelong treatment because it needs to be given only every three months.
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What helps B12 absorption?

Your intestines absorb vitamin B12 from food. A protein your stomach makes called “intrinsic factor” helps your body absorb it. When you don't have enough, you have a type of vitamin B12 deficiency anemia called “pernicious anemia.”
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Is 5000 mcg of vitamin B12 too much to take?

Since B12 is a water-soluble vitamin, it's generally considered safe, even at high doses. No Tolerable Upper Intake Level (UL) has been established for B12, due to its low level of toxicity. UL refers to the maximum daily dose of a vitamin unlikely to cause adverse side effects in the general population.
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Which is better B12 or B complex?

When it comes to the issue of vitamin B12 vs B complex, both types of vitamins are crucial. If you're lacking B12, consume more of it via supplements or food. If you're lacking vitamin B in general, consider B complex vitamins instead. Overall, both vitamins are essential nutrients.
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Which vitamin B12 is better methylcobalamin or cyanocobalamin?

The body may absorb cyanocobalamin better, while methylcobalamin has a higher retention rate. Both can prevent B12 deficiency, but methylcobalamin should be combined with adenosylcobalamin for best results.
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What is the difference between vitamin B12 and methylcobalamin?

Unlike cyanocobalamin, methylcobalamin is a naturally occurring form of vitamin B12 that can be obtained through supplements, as well as food sources like fish, meat, eggs and milk. Another major difference between methylcobalamin and cyanocobalamin is the way they're absorbed and retained within your body.
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What are the symptoms of B12 deficiency?

Vitamin B12 or folate deficiency anaemia can cause a wide range of symptoms. These usually develop gradually, but can worsen if the condition goes untreated.
  • extreme tiredness (fatigue)
  • lack of energy (lethargy)
  • breathlessness.
  • feeling faint.
  • headaches.
  • pale skin.
  • noticeable heartbeats (palpitations)
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Should you take B12 and B-complex together?

No interactions were found between Super B Complex and Vitamin B12.
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What vitamins should I not take together?

Here are six vitamin combinations you definitely shouldn't take together.
  • Magnesium and calcium/multivitamin. ...
  • Vitamins D, E and K. ...
  • Fish Oil & Gingko Biloba. ...
  • Copper and zinc. ...
  • Iron and Green tea. ...
  • Vitamin C and B12.
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How much B12 should an elderly woman take?

Dosages for Older People

Around this age, you should be getting around 2.4 micrograms of B12 a day. Not only does this mean consciously eating foods that contain vitamin B12 but it also means that you should ingest this vitamin as a supplement. By taking supplements, you will ensure that your body absorbs vitamin B12.
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Is it OK to take 1000 mcg of B12 a day?

What is the dosage for cyanocobalamin tablets? The recommended dose for treating vitamin B12 deficiency is 1000 mcg daily. The recommended dose for preventing vitamin B12 deficiency is 1500 mg or 2500 mcg (sublingual tablets) daily.
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What medications should not be taken with B12?

Certain medications can decrease the absorption of vitamin B12, including: colchicine, metformin, extended-release potassium products, antibiotics (such as gentamicin, neomycin, tobramycin), anti-seizure medications (such as phenobarbital, phenytoin, primidone), medications to treat heartburn (such as H2 blockers ...
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Does B12 raise blood pressure?

We found that a higher intake of vitamin B12 was associated with lower systolic and diastolic blood pressure and a higher intake of folic acid was associated with lower systolic blood pressure in children.
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Does coffee deplete vitamin B12?

Furthermore, caffeine interferes with the metabolism of certain B vitamins, including thiamine. However, because caffeine increases stomach acid secretion, it actually boosts the absorption of vitamin B12.
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How much B12 should you take a day?

Vitamin B12 is an essential nutrient. Fish, shellfish, meat, eggs, and dairy products are good sources of vitamin B12. The amount that should be consumed on a daily basis is called the recommended dietary allowance (RDA). The RDA is 2.4 mcg daily for people 18 years and older.
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What vitamins should I take with B12?

Folate and B12 work together to produce S-adenosylmethionine (SAMe), a compound involved in immune function and mood. Vitamins B12, B6, and B9 work together to control blood levels of the amino acid homocysteine.
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Why is hydroxocobalamin preferred over cyanocobalamin?

However, in the United States cyanocobalamin is preferred because hydroxycobalamin may induce inappropriate immune responses in some patients Sweetman (2003).
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Is hydroxocobalamin the same as B12?

Hydroxocobalamin is a manufactured version of the vitamin B12. It is used to treat and prevent vitamin B12 deficiency anaemia (when you have low levels of this vitamin in the body). The most common cause of vitamin B12 deficiency in the UK is pernicious anaemia. Hydroxocobalamin is only available on prescription.
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What are the side effects of cyanocobalamin?

Side Effects
  • Abdominal or stomach pain.
  • bleeding from the gums or nose.
  • blue lips and fingernails.
  • chest pain.
  • coughing that sometimes produces a pink frothy sputum.
  • decreased urine output.
  • difficult, fast, noisy breathing, sometimes with wheezing.
  • difficulty with swallowing.
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Is it better to take B-complex or individual B vitamins?

People can buy B vitamins as individual supplements if they are deficient in only one type. However, some evidence suggests that a full B-complex vitamin supplement may be a better choice, even if a person has just one deficiency.
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