What is PVP in pharmacy?

Polyvinylpyrrolidone (PVP) is a water-soluble polymer obtained by polymerization of monomer N-vinylpyrrolidone. PVP is an inert, non-toxic, temperature-resistant, pH-stable, biocompatible, biodegradable polymer that helps to encapsulate and cater both hydrophilic and lipophilic drugs.

What is PVP chemical used for?

PVP is a versatile ingredient used in the cosmetics and beauty industry as a binder, film former, emulsion stabilizer, suspending agent, and hair fixative, and is seen primarily in products such as mascara, eyeliner, hair conditioners, hair sprays, shampoos, and other hair care products.

What is PVP coating?

Polyvinylpyrrolidone (PVP), also commonly called polyvidone or povidone, is a water-soluble polymer made from the monomer N-vinylpyrrolidone.

How is PVP produced?

PVP can be prepared by free-radical polymerization from its monomer N-vinylpyrrolidone in the presence of AIBN as an initiator as shown in Figure 1.20 [87,88]. Figure 1.20. Synthesis of polyvinylpyrrolidone. The PVP was used as a blood plasma expander for trauma victims.

Is PVP a binder?

In the present study, hydrophilic polyvinylpyrrolidone (PVP) was used both as a binder and a pore-former in EC coated pellets to deliver sparingly water-soluble topiramate, and the key factors that influenced drug release were identified.

a-PVP pharmacology and mechanism

Is PVP a thickener?

PVP (polyvinylpyrrolidone) is a water-soluble polymer with film-forming properties. It is widely used in skincare and cosmetics. PVP has many functions including thickening, film-forming and hairstyling.

Is PVP a surfactant?

PVP is commonly used as a surfactant or structure directing reagent in the chemical process to regulate nucleation and crystal growth, reduced surface tension and stabilized metal nanoparticles [25].

Is PvP a plastic?

These two polymer ingredients are not solid plastics but are dissolved and used in solution within the product. PVP is water-soluble while Styrene/acrylate/ammonium methacrylate copolymer is oil-soluble.

What are the advantages of PvP?

PVP is an inert, non-toxic, temperature-resistant, pH-stable, biocompatible, biodegradable polymer that helps to encapsulate and cater both hydrophilic and lipophilic drugs. These advantages enable PVP a versatile excipient in the formulation development of broad conventional to novel controlled delivery systems.

What is PvP and PvE?

Player versus environment or player versus enemy (PvE, also known as player versus monster (PvM)), is a term used for both single player and online games, particularly MMORPGs, CORPGs, MUDs, other online role-playing video games and survival games to refer to fighting computer-controlled enemies—in contrast to PvP ( ...

How do you make a PVP solution?

In brief, the PVP solution was prepared by dissolving 0.5 g of PVP in 10 mL of deionized water at room temperature for 2 h under agitation.

What is PVP in DNA extraction?

As PVP forms a hydrogen bond with the phenolic compounds during centrifugation and separates them from the DNA, it can prevent DNA contamination by phenolic compounds [12], [29]. Our study confirmed that the addition of PVP in the DNA extraction process increases the concentration of DNA.

Is PVP edible?

However the polymer PVP in its pure form is so safe that not only is it edible by humans, but it was used as a blood plasma expander for trauma victims after the first half of 20th century. It is used as a binder in many pharmaceutical tablets; being completely inert to humans, it simply passes through the body.

Is PVP a silicone?

To understand how this silicone made a better hairspray, it helps to understand how the hairspray works in the first place. When you spray it on, the polyvinylpyrrolidone forms a thin coating on the hair. This coating is stiff and keeps the hair from moving around.

What is povidone used for?

POVIDONE IODINE (poe-vee-don ahy-uh-din) is used on the skin to decrease risk of infection. This medicine is also used as a surgical hand scrub and to wash the skin and surface of the eye before surgery to help prevent infections.

What does PVP mean in medical terms?

PVP. Peripheral Venous Pressure. Health, Healthcare, Diagnosis.

Is PVP a polymer?

Polyvinylpyrrolidone (PVP), also called polyvidone or povidone, is a biodegradable, water-soluble polymer, derived from its monomer N-vinylpyrrolidone.

What is povidone K30?

General description. Polyvinylpyrrolidone (PVP), also commercially known as K30, is a water soluble polymer. It has a hygroscopic nature with good adhesive properties. It has a stable pH and has the ability to form transparent films.

Is PVP ingredient safe?

Polyvinylpyrrolidone (PVP) is considered a safe ingredient and has been rated as a low hazard ingredient by the Cosmetics Database.

Is PVP a natural ingredient?

It is a synthetic ingredient that is derived from petroleum. PVP (also known as Polyvinylpyrrolidone) was the main ingredient in the first really successful hairsprays in the early 1950s. This polymer worked as a hairspray because it was soluble in water. This meant it could be rinsed out when you wash your hair.

Is polyvinylpyrrolidone safe for skin?

The CIR Expert Panel evaluated the scientific data and concluded that PVP (polyvinyl pyrrolidone) was safe as used in cosmetics and personal care products.

Is PVP a reducing agent?

PVP can serve as a surface stabilizer, growth modifier, nanoparticle dispersant, and reducing agent. As shown with examples, its role depends on the synthetic conditions.

What is K value in povidone?

Povidone is a chain polymer of 1-vinyl-2-pyrrolidone. It contains NLT 11.5% and NMT 12.8% of nitrogen (N: 14.01), calculated on the anhydrous basis. It has the nominal K-value of NLT 10 and NMT 120.

Is PVP biodegradable?

Polyvinylpyrrolidone (PVP) is a frequently used polymer in the pharmaceutical and foodstuff industries. Because it is not subject to metabolic changes and is virtually nondegradable, trace concentrations of PVP are often found in community wastewaters.