What is multisystem inflammatory syndrome in adults (MIS-A) and how is it related to COVID-19?

MIS-A is characterized by fever, elevated inflammatory markers, and multiple organ system involvement (usually cardiovascular and gastrointestinal manifestations). These cases series also illustrate that previous COVID-19 infection may be asymptomatic (Bastug, March 2021; Morris, October 2020).
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What is multisystem inflammatory syndrome in children in the context of COVID-19?

Multisystem inflammatory syndrome (MIS) is a rare but serious condition associated with COVID-19 in which different body parts become inflamed, including the heart, lungs, kidneys, brain, skin, eyes, or gastrointestinal organs. MIS can affect children (MIS-C) and adults (MIS-A).
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Which organ system is most often affected by COVID-19?

COVID-19 is a disease caused by SARS-CoV-2 that can trigger what doctors call a respiratory tract infection. It can affect your upper respiratory tract (sinuses, nose, and throat) or lower respiratory tract (windpipe and lungs).
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What is the MIS-A during the COVID-19 pandemic?

MIS-A is a group of symptoms that develops as a complication of coronavirus disease 2019 (COVID-19). Inflammation develops in areas such as your heart, digestive system, skin, or brain.

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What is multisystem inflammatory syndrome in children (MIS-C)?

Multisystem inflammatory syndrome in children (MIS-C) is a serious condition associated with COVID-19 where different body parts can become inflamed, including the heart, lungs, kidneys, brain, skin, eyes, or gastrointestinal organs.
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Can COVID-19 cause pediatric multisystem inflammatory syndrome (PMIS) in children?

Some children and teens who are in the hospital with the disease have an inflammatory syndrome that may be linked to the new coronavirus. Doctors call it pediatric multisystem inflammatory syndrome (PMIS). Symptoms include a fever, a rash, belly pain, vomiting, diarrhea, and heart problems.
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When was COVID-19 Multisystem inflammatory syndrome in children (MIS-C) first diagnosed?

Multisystem inflammatory syndrome in children (MIS-C) was first identified in April 2020 by doctors at children's hospitals in the United States and the United Kingdom. The condition has also been called pediatric inflammatory multisystem syndrome (PIMS).

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What are the common symptoms of Multisystem Inflammatory Syndrome (MIS-C)?


The most common symptoms are fever with a red rash, red eyes, red lips and red palms and soles. Abdominal pain, vomiting and diarrhea also occur. Half of the patients develop trouble breathing.

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Is the Mu variant of COVID-19 a 'variant of interest'?


Although the World Health Organization continues to classify Mu as a 'variant of interest' globally, the CDC lists Mu simply as a 'variant being monitored. ' The CDC counts 10 variants in the variant being monitored group, including three once considered variants of concern: the Alpha, Beta, and Gamma

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What are the new changes to the COVID-19 Economic Injury Disaster Loan program?


Key changes announced included: Increased COVID EIDL Cap. The SBA lifted the COVID EIDL cap from $500,000 to $2 million. Loan funds can be used for any normal operating expenses and working capital, including payroll, purchasing equipment, and paying off debt.

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Can COVID-19 damage organs?


COVID-19 can cause lasting damage to multiple organs, including the lungs, heart, kidneys, liver and brain. SARS CoV-2 first affects the lungs through the nasal passages. When the lungs are severely affected, it can affect the heart.

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Can COVID-19 affect the digestive system?

In some instances, digestive symptoms are reported as the initial presentation of COVID-19 (15). These findings suggest that the virus can impair the digestive system and may explain the range of digestive symptoms seen in COVID-19, including diarrhea, nausea, vomiting, and diminished appetite (16).
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Can COVID-19 spread through sexual intercourse?

Although COVID-19 has been detected in semen and feces, currently we do not think that the virus is spread through the sexual act. But, given that the virus is spread through respiratory droplets—which are much more likely to be shared when in close contact with another person—many sexual acts will be considered high risk. So, as the New York City Department of Health details in its safer sex and COVID-19 fact sheet, minimizing risks by exploring other avenues of meaningful interaction is suggested and recommended.
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What are the most common reactions to the COVID-19 vaccine in children?


Reactions were reported most frequently on the day after vaccination for both doses. The most frequently reported reactions after either dose were injection site pain, fatigue, and headache. Fever was more frequently reported after dose 2 (4,001; 13.4%) than dose 1 (3,350; 7.9%).

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What conditions put children at higher risk for COVID-19?


Like adults, children with obesity, diabetes, asthma or chronic lung disease, sickle cell disease, or who are immunocompromised can also be at increased risk for getting very sick from COVID-19.

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What are the common side effects of the Pfizer-BioNTech COVID-19 vaccine on children?


For children and teens ages 12 through 17 years, the most commonly reported side effects after getting the first two doses of the Pfizer-BioNTech COVID-19 vaccine are: Tiredness. Fever. Headache.

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Are there different types of coronaviruses other than COVID-19?

Coronaviruses didn't just pop up recently. They're a large family of viruses that have been around for a long time. Many of them can cause a variety of illnesses, from a mild cough to severe respiratory illnesses. The new (or “novel”) coronavirus that causes COVID-19 is one of several known to infect humans.

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Should I be worried about getting the COVID-19 Omicron variant?


While some have suggested that most people will eventually get the coronavirus, you should do your best to avoid infection with Omicron—there is no justification for deliberately getting infected so you have what you think will be a mild illness that will provide you with more immunity going forward, the doctors say.

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What are some symptoms of the new Omicron variant of Covid-19?

Katherine Poehling, an infectious disease specialist and member of the Advisory Committee on Immunization Practices, told NBC News in January that a cough, congestion, runny nose and fatigue appear to be prominent symptoms with the omicron variant.
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Can the Omicron variant cause long-term COVID-19 symptoms?


The possibility of long COVID. While omicron may cause less severe symptoms, this may not mean a decreased risk of long-term sickness.

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What are some of the symptoms of Post-acute sequelae from COVID-19?

Those suffering from post-acute sequelae of COVID-19 frequently have difficulty concentrating and memory problems, sometimes called “brain fog.” This impairment is a common symptom in those with severe fatigue of any cause.

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What is the treatment for Multisystem Inflammatory Syndrome in Adults (MIS-A) from COVID-19 in adults?


For now, steroids, IVIG, and supportive care treatments have been suggested in the literature for MIS-A (Ahmad, May 2021; Davogustto, May 2021). Based on current knowledge, CDC recommends COVID-19 vaccination as the best protection from MIS-A.

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Are Multisystem Inflammatory Syndrome in Children (MIS-C) and COVID-19 related?

We do not yet know what causes MIS-C. However, we know that many children with MIS-C had the virus that causes COVID-19, or had been around someone with COVID-19. MIS-C can be serious, even deadly, but most children who were diagnosed with this condition have gotten better with medical care.
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When was the Omicron variant of COVID-19 detected in the U.S.?


The B.1.1.529 (Omicron) variant, first detected in November 2021, was responsible for a surge in U.S. infections with SARS-CoV-2, the virus that causes COVID-19, during December 2021–January 2022 (1).

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When was the official name of SARS-CoV-2 announced?

On 11 February 2020, the International Committee on Taxonomy of Viruses adopted the official name "severe acute respiratory syndrome coronavirus 2" (SARS-CoV-2).
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