What is considered a high ferritin level postmenopausal woman?

Results: Among these postmenopausal women, the median plasma ferritin concentration was 73.8 ng/mL (interquartile range: 41.6–125.8 ng/mL), 2.7% were iron depleted (ferritin concentration < 12 ng/mL), and 9.8% had an elevated ferritin concentration (> 200 ng/mL).

What is a normal ferritin level for a 60 year old woman?

20 to 250 ng/mL for adult males. 10 to 120 ng/mL for adult females, 18 to 39 years. 12 to 263 ng/mL for females, 40 years and older.

Can menopause cause high ferritin levels?

Here, we show that although estrogen decreases by 90%, a concurrent but inverse change occurs in iron levels during menopausal transition. For example, levels of serum ferritin are increased by two- to threefold from before menopause to after menopause.

What is dangerously high ferritin levels symptoms?

High ferritin levels

Symptoms of excess ferritin include: stomach pain. heart palpitations or chest pains. unexplained weakness.

What is a toxic ferritin level?

Mild-to-moderate toxicity generally manifests at levels of 350-500 mcg/dL. Persistently symptomatic patients with serum iron levels higher than 350 mcg/dL should be admitted. Hepatotoxicity usually is observed at levels higher than 500 mcg/dL. Levels higher than 800 mcg/dL are associated with severe toxicity.

Ferritin Levels in Women: Menstruating vs Post Menopausal

Is 400 ferritin too high?

Many laboratories consider serum ferritin levels greater than 200 ng/mL in women and greater than 300 ng/mL in men to be abnormal.

Is 600 a high ferritin level?

In a healthy man in his 30s or 40s, a stable elevated ferritin level of 500 – 600 μg/l is suggestive of preclinical hereditary haemochromatosis. Mildly elevated serum ALT and fatigue, as in our patient, are common initial symptoms of the transition to clinical stage disease.

Is ferritin a tumor marker?

Ferritin: a tumor marker expressed by renal cell carcinoma.

What cancers cause high ferritin levels?

Iron overload, inflammation, liver disease, and malignancy are conditions that lead to elevated serum ferritin [7-11]. Pancreatic cancer, colorectal cancer, lung cancer, T-cell lymphoma, and hepatocellular carcinoma are associate with high serum ferritin [7-12].

What should I do if my ferritin level is high?

If you're experiencing symptoms of low or high iron and ferritin levels, contact your healthcare provider as soon as possible. Seeing an abnormal test result can be stressful. Know that having a high or low level of ferritin doesn't necessarily mean you have a medical condition and need treatment.

Can hormones affect ferritin levels?

In our population-based cross-sectional study, data showed that levels of serum ferritin were negatively associated with sex hormones.

Does HRT lower ferritin?

Current HRT use was associated with lower ferritin (β=-34.13, p=0.0002), controlling for potential breakthrough bleeding with a hysterectomy variable.

Can you have high iron levels and not have hemochromatosis?

Conclusion. In a patient with signs and symptoms of tissue iron overload and high serum ferritin levels, low or normal transferrin saturation should alert the physician to other - primary as well as secondary - causes of iron overload besides hemochromatosis.

What should female ferritin levels be?

The results may vary slightly among laboratories, but in general, normal ferritin levels range from 12 to 300 nanograms per milliliter of blood (ng/mL) for males and 12 to 150 ng/mL for females.

Do ferritin levels increase with age?

Ferritin level can increase with aging as a part of the low-grade chronic inflammatory state, which occurs, with aging, so called inflammaging. Aging is associated with low-grade chronic inflammation [5].

What is the ideal ferritin level for a woman?

Optimal ferritin levels for females: 12 to 263 ng/mL. Optimal ferritin levels for athletes: 60 to 300 ng/ mL. Optimal ferritin levels for children: 7 to 140 ng/mL.

Can high ferritin mean nothing?

Higher than normal ferritin levels can mean you have too much iron in your body. Conditions that cause increased iron levels include liver disease, alcohol abuse, and hemochromatosis, a disorder that can lead to cirrhosis, heart disease, and diabetes.

What type of inflammation causes high ferritin?

Ferritin is an acute phase reactant and a marker of acute and chronic inflammation. It is elevated in a wide range of inflammatory conditions, including chronic kidney disease, rheumatoid arthritis, and other autoimmune disorders, acute infections, and cancer [1, 2].

Does high ferritin mean liver disease?

Serum ferritin (SF) levels are commonly elevated in patients with nonalcoholic fatty liver disease (NAFLD), due to systemic inflammation, increased iron stores or both.

Is ferritin high in leukemia?

Extremely high serum ferritin levels were seen in acute myeloblastic leukemia before treatment and in blastic crisis of chronic myeloid leukemia (ie, 21-fold increased serum ferritin concentrations). Patients with acute myeloblastic leukemia in complete remission had their ferritin concentrations decreased to normal.

Is ferritin an inflammatory marker?

Ferritin is a marker of inflammation rather than iron status in overweight and obese individuals. Being an acute phase reactant, a high ferritin level secondary to subclinical inflammation in overweight and obese people may mask an underlying iron deficiency.

Can lymphoma cause high ferritin levels?

The study included 207 patients with Hodgkin lymphomas, 196 patients with low grade malignant Non Hodgkin lymphomas and 132 patients with high grade malignant Non Hodgkin lymphomas of different tumor stages. Increased serum ferritin concentrations were found in 54% of the unselected patients.

What does a ferritin level of 700 mean?

Serum ferritin levels >700 ng/ml were associated with higher incidence of aGVHD grade III-IV (p=0.002), mainly intestinal aGHVD (p=0.014) but we did not find higher incidence of chronic GVHD in the allogeneic group.

Is a ferritin level of 1000 high?

Research demonstrates that a ferritin level higher than 1000 µg/L is associated with a high prevalence (20%–45%) of advanced fibrosis and cirrhosis in hereditary hemochromatosis.

What does a ferritin level of 400 mean?

A serum ferritin level above 200 ng/mL for premenopausal women or 400 ng/mL for men (in the absence of inflammation, cancer or hepatitis) supports the diagnosis of hereditary hemochromatosis.