What is classical lymphoma?

Classical Hodgkin's lymphoma is the more common type of this disease. People diagnosed with this type have large lymphoma cells called Reed-Sternberg cells in their lymph nodes. Subtypes of classical Hodgkin's lymphoma include: Nodular sclerosis Hodgkin's lymphoma. Mixed cellularity Hodgkin's lymphoma.
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Is classical Hodgkin lymphoma curable?

Classical Hodgkin lymphoma is considered a highly curable disease; however, 20% of patients cannot be cured with standard first-line chemotherapy and have a dismal outcome. Current clinical parameters do not allow accurate risk stratification, and personalized therapies are lacking.
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What is the difference between classical and Hodgkin lymphoma?

It's more common in older people but can occur in young people. The main difference between this type and classical Hodgkin lymphoma is that in the nodular lymphocyte predominant type there are very few Reed-Sternberg cells.
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Is classical Hodgkin lymphoma aggressive?

Classical Hodgkin Lymphoma (cHL) Classical Hodgkin Lymphoma (cHL) is a fast growing (aggressive) B-cell lymphoma. However, cHL usually responds very well to standard treatment with chemotherapy.
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What causes classical Hodgkin's lymphoma?

Hodgkin lymphoma is caused by a change (mutation) in the DNA of a type of white blood cell called B lymphocytes. The exact reason why this happens isn't known. The DNA gives the cells a basic set of instructions, such as when to grow and reproduce.
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Hodgkin’s lymphoma | Hodgkin’s Disease | Reed-Sternberg Cell



Which lymphoma is worse Hodgkins or non-Hodgkin's?

The prognosis of Hodgkin's lymphoma is also better than that of non-Hodgkin's lymphoma since non-Hodgkin's lymphoma is often diagnosed at a more advanced stage. Both forms of blood cancer are treatable when caught early, however.
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What is the treatment for classical Hodgkin lymphoma?

Treatment for classical Hodgkin lymphoma. Treatment for classical Hodgkin lymphoma usually involves chemotherapy, sometimes followed by radiotherapy. The exact treatment you need depends on the stage of your disease and how it is affecting you.
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What type of lymphoma is not curable?

Lymphoplasmacytic lymphoma or Waldenstrom macroglobulinemia.

It's found mainly in the bone marrow, lymph nodes, and spleen. This type of lymphoma can't be cured.
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Can you live 20 years with Hodgkin lymphoma?

The 20-year actuarial rates of survival were 78%, 78%, and 46%, respectively, for patients aged 16 or less, 17 to 39, and 40 years or older at diagnosis. Hodgkin's disease diagnosed at age 40 or older was a significant risk factor for all causes of death.
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What are the 3 main types of lymphoma?

Each type of lymphoma can cause different symptoms and need different treatment.
  • Hodgkin lymphoma. ...
  • Non-Hodgkin lymphoma. ...
  • Chronic lymphocytic leukaemia (CLL) and small lymphocytic lymphoma (SLL) ...
  • Lymphoma in children and young people.
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What is classic Hodgkin's disease?

Classical Hodgkin's lymphoma is the more common type of this disease. People diagnosed with this type have large lymphoma cells called Reed-Sternberg cells in their lymph nodes. Subtypes of classical Hodgkin's lymphoma include: Nodular sclerosis Hodgkin's lymphoma.
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What is classic Hodgkin's lymphoma stage 4?

Stage 4. Stage 4 means one of the following: your lymphoma is in an extranodal site and lymph nodes are affected. your lymphoma is in more than one extranodal site, for example the liver, bones or lungs.
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Can you live a long life with Hodgkin's lymphoma?

Survival for all stages

Generally, for people with Hodgkin lymphoma in England: around 90 out of 100 (around 90%) survive their cancer for 1 year or more after diagnosis. more than 80 out of 100 (more than 80%) survive their cancer for 5 years or more after diagnosis.
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Which type of Hodgkin lymphoma has best prognosis?

Nodular sclerosing Hodgkin lymphoma has a higher survival rate than other types of classic Hodgkin lymphoma, with the five-year survival rate being greater than 90%.
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What are the warning signs of lymphoma?

Signs and symptoms of lymphoma may include:
  • Painless swelling of lymph nodes in your neck, armpits or groin.
  • Persistent fatigue.
  • Fever.
  • Night sweats.
  • Shortness of breath.
  • Unexplained weight loss.
  • Itchy skin.
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What were your first signs of lymphoma?

Here are 11 early signs of lymphoma:
  • Swollen lymph nodes: ...
  • Fever and/or chills: ...
  • Night sweats: ...
  • Swelling of the abdomen: ...
  • Loss of appetite: ...
  • Persistent, overwhelming fatigue: ...
  • Easy bruising or bleeding: ...
  • Coughing, chest pressure, or shortness of breath:
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Where does lymphoma spread to first?

NHL usually starts in an area of lymph nodes. When it spreads to an organ or tissue outside of the lymph nodes, it is called extranodal spread.
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Who is most at risk for lymphoma?

Age. Getting older is a strong risk factor for lymphoma overall, with most cases occurring in people in their 60s or older . But some types of lymphoma are more common in younger people.
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How many rounds of chemo do you need for lymphoma?

Treatment for many patients is chemotherapy (usually 2 to 4 cycles of the ABVD regimen), followed by radiation to the initial site of the disease (involved site radiation therapy, or ISRT). Another option is chemotherapy alone (usually for 3 to 6 cycles) in selected patients.
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Do you lose your hair with chemo for lymphoma?

Hair loss is quite common in people who are treated with chemotherapy; overall, around 2 in 3 people experience hair loss. Chemotherapy kills lymphoma cells, but it can also destroy healthy cells, particularly those that normally divide quickly. Hair follicles produce hair.
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Is non-Hodgkin's lymphoma a death sentence?

What is the survival rate for non-Hodgkin lymphoma? According to the American Cancer Society, about 71 percent of people of all races with non-Hodgkin lymphoma are still alive five years after diagnosis. Children tend to fare better, with 87 percent living for at least five years after diagnosis.
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Which lymphoma is easier to treat?

Hodgkin lymphoma is considered one of the most treatable cancers, with more than 90 percent of patients surviving more than five years. Most patients with Hodgkin lymphoma live long and healthy lives following successful treatment.
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Which has better survival rate Hodgkin's or non-Hodgkin lymphoma?

More than 86 percent of patients diagnosed with Hodgkin lymphoma survive five years or more. About 70 percent of patients diagnosed with non-Hodgkin lymphoma survive five years or more. There are six varieties of Hodgkin lymphoma.
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