What is Blaschkitis?

Blaschkitis is an acquired inflammatory dermatitis that some consider an adult variant of lichen striatus

lichen striatus

Lichen striatus is an uncommon condition typically seen in children that presents as elevated pink papules that coalesce to form one or more linear, potentially scaly bands along the Blaschko lines. Lichen striatus is benign and self-resolving and does not require extensive investigations or treatment.

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. In 1990, Grosshans proposed that blaschkitis was distinct from lichen striatus, identifying several criteria by which the 2 differ, including typical patient age, distribution, time course, and histopathology.

What causes Blaschkitis?

Emotional stress, medications (such as certolizumab and metronidazole), trauma, and viral infections have been implicated as triggers for blaschkitis [1,11,12]. Blaschkitis has been reported to occur with features of other skin diseases such as lichen nitidus, lichen striatus, and lupus erythematosus [1,3,11].

Why do I get eczema on one side of my body?

Acquired blaschkoid dermatitis is unilateral — it only affects one side of the body. As its name would suggest, the skin lesions occur along Blaschko lines. The lesions may resolve spontaneously but they have a tendency to relapse over time, especially at times of stress.

What is blaschko's lines?

Blaschko's lines, also called the lines of Blaschko, are lines of normal cell development in the skin. These lines are invisible under normal conditions, but can become apparent as whorls, patches, streaks or lines in a linear or segmental distribution over the skin due to a mosaic skin condition.

How is lichen striatus treated?

Because lichen striatus is a self-limited disorder and because the lesions spontaneously regress within 3-12 months, no treatment is needed. The patient and family should be reassured. However, emollients and topical steroids may be used to treat associated dryness and pruritus, if present.

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What does lichen striatus look like?

Lichen striatus (LY kuhn stry AY tuhs) is a rash that appears as pink or lightly-colored, scaly, flat bumps. Over the following weeks, these bumps come together to form a line or band on the skin. Sometimes the rash can appear inflamed or redder, with a thicker scale.

What causes lichen striatus in adults?

The condition is triggered by an “immunologic reaction to an infection,” and that this results in a cascade of events including the methylation or demethylation of a portion of a “partially silenced genomic element.” Also, it has been reported that lichen striatus is triggered as a result of a viral infection of ...

Are human females covered in stripes?

But what is less well known is that humans actually have stripes of their own. Our skin is covered in stripes that run up and down the arms and around the torso. To the human eye they are invisible, but they can be seen under UV light.

What is Bart's syndrome?

Barth syndrome is a rare condition characterized by an enlarged and weakened heart (dilated cardiomyopathy ), weakness in muscles used for movement (skeletal myopathy), recurrent infections due to small numbers of white blood cells (neutropenia), and short stature.

What are human Stripes called?

They're called Blaschko Lines: Blaschko Lines follow the same pattern on all people. They run down the arms and legs. They curve around the sides, like tiger stripes.

What is the root cause of eczema?

Eczema (atopic dermatitis) is caused by a combination of immune system activation, genetics, environmental triggers and stress. Your immune system. If you have eczema, your immune system overreacts to small irritants or allergens. This overreaction can inflame your skin.

What cures eczema fast?

Does Covid make eczema worse?

There is no evidence to suggest that people with eczema are more likely to develop Covid-19 or to experience a more severe form of the condition if they do develop it.

How do you get lichen striatus?

The cause of lichen striatus is unknown. Possibly genetic factors or environmental triggers have a role to play in its development. The eruption affects the lines of Blaschko, which are thought to be embryonic in origin. Over 50% of cases occur in children aged between 5 and 15 years.

What is linear psoriasis?

Linear psoriasis is an unusual clinical variation of psoriasis that manifests segmentally along the lines of Blaschko. A major differential diagnosis is inflammatory linear verrucous epidermal nevus (ILVEN).

What is linear Lichen Planus?

Linear lichen planus (LLP) is a rare form of lichen planus, which is a condition that affects the skin and/or mouth. In LLP, specifically, affected people develop itchy, purple, flat-topped papules (bumps) in a linear distribution along the lines of Blaschko.

What is Highlander syndrome?

The development of highlander syndrome in human patients suggests that humans might possess the genes that enable the property of eternal youth. The actualization of eternal youth is a long-held dream, and numerous studies have been performed to elucidate the mechanisms of aging and to achieve eternal youth.

What is Tucker syndrome?

Tucker Syndrome is a rare condition that causes droopy eyelids and the paralysis of the vocal chords. Individuals with Tucker Syndrome may experience symptoms such as premature birth, droopy eyelids, weak leg or arm muscles, laryngeal abnormality and vocal cord paralysis.

What is Adams Oliver Syndrome?

Adams-Oliver syndrome (AOS) is a rare inherited condition present at birth that involves changes to the limbs and scalp. Symptoms may include areas of missing skin on the scalp, limb abnormalities, heart defects, neurological concerns, and issues with the eyes.

Can dogs see our stripes?

And some people with a genetic mutation have stripes clearly visible. The stripes were discovered by German dermatologist Alfred Blaschko 75 years ago. Also since cats and dogs can see UV light they can see our stripes.

Can cats see UV?

The kitty may be seeing things that human eyes can't. Unlike humans, many animals see in ultraviolet, and a study now suggests that cats, dogs and other mammals can, too. Knowing these animals see things invisible to humans could shed some light on the animals' behavior, the researchers say.

Can Covid cause lichen striatus?

1 The same study also reported a female predominance of 90% in cutaneous reactions to COVID-19 vaccination. Adding to this body of evidence, we, herein, describe an eruption of lichen striatus occurring several days after COVID-19 vaccination in a middle-aged woman.

Is lichen striatus an autoimmune disease?

Some scientists have suggested that lichen striatus is an autoimmune response to inflamed T cells. Environmental stimuli, such as infection or trauma, have also been implicated in its pathogenesis, as cases in unrelated individuals have been described.

What does a linear rash mean?

Linear epidermal naevi

They are thought to be due to point mutations in keratin genes causing malformation in the epidermis. They may be present at birth or develop in infancy. At first they appear as flat, itchy, pigmented plaques but may increase in size and develop a thickened warty surface.