What is better than hydroquinone for melasma?

This study revealed that intralesional tranexamic acid is the more effective and safe therapeutic modality in treating melasma than topical 4% hydroquinone.
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What is alternative to hydroquinone for melasma?

Silymarin cream may be an effective and tolerable alternative to hydroquinone in patients with melasma, according to a study.
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What is more effective than hydroquinone?

Arbutin. According to Dr. Green, “Arbutin is a natural form of hydroquinone derived from the bearberry plant. It is a safer and effective alternative to hydroquinone and is less cytotoxic to the melanocytes.” Use it gradually during the first few weeks to make sure your skin doesn't react.
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What is the most effective treatment for melasma?

Triple combination cream (hydroquinone, tretinoin, and corticosteroid) remains the most effective treatment for melasma, as well as hydroquinone alone. Chemical peels and laser- and light-based devices have mixed results. Oral tranexamic acid is a promising new treatment for moderate and severe recurrent melasma.
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Which cream is best for remove melasma?

Hydroquinone: This is a common treatment for melasma. It is applied to the skin and works to even out the skin tone.
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Is hydroquinone safe? Q



What can I alternate with hydroquinone?

Below, we investigate the agents individually:
  • Mequinol. Mequinol is the main alternative prescription alternative to hydroquinone. ...
  • Retinoids. ...
  • Azelaic Acid. ...
  • Arbutin. ...
  • Kojic Acid. ...
  • Licorice Extract. ...
  • Ascorbic Acid (Vitamin C) ...
  • N-Acetylglucosamine.
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Which is better for melasma hydroquinone or azelaic acid?

Over a period of 24 weeks, 73% of the azelaic acid patients, compared with 19% of the hydroquinone patients, had good to excel- lent overall results, as measured by the reduction of melasma pigmentary intensity and lesion size. Tran- sient mild to moderate irritant reactions were initially seen with both test drugs.
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What do dermatologists recommend for hyperpigmentation?

What are the best treatments for hyperpigmentation?
  • Skin lightening creams. The first option, of course, is skin lightening creams. ...
  • Retinoids. ...
  • Laser peel. ...
  • Chemical peel. ...
  • Skin acids. ...
  • Microdermabrasion. ...
  • IPL or Intense pulsed-light therapy. ...
  • Dermabrasion.
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How long does azelaic acid take to fade melasma?

Depending on the strength of your prescription and frequency of use, azelaic acid can take between 6-8 weeks to be effective. Prescription products typically produce visible results in roughly two months, whereas OTC products often take twice as long.
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Why you should not use hydroquinone?

FDA has received reports of serious side effects including skin rashes, facial swelling, and ochronosis (discoloration of skin) from the use of skin lightening products containing hydroquinone.
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Is arbutin better than hydroquinone?

Arbutin is a naturally occurring derivative of hydroquinone. It is believed to be one of the best alternatives to hydroquinone as it provides the skin-lightening effect of hydroquinone without some of the risks.
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What is a natural substitute for hydroquinone?

5 Super Effective Natural Hydroquinone Alternatives
  • Kojic Acid.
  • Arbutin.
  • Vitamin C.
  • Retinol.
  • Niacinamide.
  • Mushroom.
  • Licorice/Glycyrrhizin.
  • Azelaic acid.
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How do I get rid of melasma ASAP?

Hydrocortisone (a topical corticosteroid): Hydrocortisone helps fade the color caused by melasma. It can also lessen the likelihood of dermatitis that may be caused by other agents. Hydroquinone: This medication is applied as a cream or lotion. It goes directly onto the melasma patches at night for two to four months.
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What is the permanent cure for melasma?

Triggered by factors like birth control, menopause and pregnancy, the condition usually subsides on its own. It can be treated by dermatologists as well, but there is no permanent cure for this skin issue.
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Why is it so hard to get rid of melasma?

Because the condition is fueled primarily by sunlight and female hormones, there's no true way to cut off the stimulus for melasma. In other words, you may get encouraging results from a gentle chemical peel, but they're likely to be short-lived. Eventually, nature will regain the upper hand.
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Which is better kojic acid or hydroquinone?

Topical Hydroquinone has a faster onset of action and higher efficacy compared to kojic acid with Vitamin C.
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Which is safer kojic acid or hydroquinone?

The chemical hydroquinone is the predecessor to kojic acid. It's deemed safe and accomplishes the same goal as kojic acid. If you have side effects with kojic acid, consider hydroquinone instead.
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What percentage of azelaic acid is effective for melasma?

Clinical studies of patients with melasma have shown that topical 20 percent azelaic acid is superior to 2 percent hydroquinone and as effective as 4 percent hydroquinone, without the latter's undesirable side effects.
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Does melasma come back after tranexamic acid?

Despite the success, however, relapses occurred. After an average of 7 months post-oral tranexamic acid treatment, 137 patients (27.2 percent) saw melasma recurrence. An additional 7.1 percent experienced transient side effects, including abdominal bloating and headaches, investigators said.
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What completely clears hyperpigmentation?

Chemical peels, laser therapy, microdermabrasion, or dermabrasion are all options that work similarly to rid skin of hyperpigmentation. These procedures work to gently remove the top layer of your skin where the dark spots lie.
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What do celebs do for hyperpigmentation?

Pigment inhibitors, antioxidants, broad-spectrum physical sunscreen, wide-brimmed hats, peels and microdermabrasion.
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What do estheticians use for hyperpigmentation?

Suggested treatments: Chemical peels (salicylic acid, lactic acid and glycolic acids, Trichloracetic acid) work well. Nonablative laser devices such as microneedling are okay too. When it comes to lasering, Dr. Jones says “lower intensities of laser treatments, spread out over multiple visits is safest.”
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How can I lighten my dark skin without hydroquinone?

The Best Skin Lightening Creams Without Hydroquinone.
  1. Medik8 C-Tetra Cream. ...
  2. Antipodes Manuka Honey Skin Brightening Day Cream. ...
  3. Dermalogica BioLumin-C Gel Moisturiser. ...
  4. Murad Environmental Shield City-Skin Overnight Detox Moisturiser. ...
  5. SK-II Cellumination Deep Surge EX. ...
  6. Laneige Radian C Cream.
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