What is better HRT or antidepressants?

Conclusions: The data suggest that antidepressant and antianxiety medications are more helpful than HRT in relieving peri- and postmenopausal depression or anxiety. However, most women managed the mood changes associated with menopause without psychopharmacologic intervention.
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Can you take antidepressants instead of HRT?

Antidepressants, such as citalopram or venlafaxine in low doses, are sometimes prescribed to help with hot flushes and night sweats for women who cannot take HRT as a firstline treatment.
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Is HRT good for anxiety and depression?

Many women start hormone therapy to help with physical symptoms like hot flashes, but hormone replacement may also help alleviate emotional symptoms like depression symptoms and mood changes.
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Which antidepressant is best for menopause?

SSRIs – The selective serotonin receptor inhibitors (SSRIs) are the class of antidepressants used most commonly for treating hot flashes. A form of paroxetine (sample brand name: Brisdelle) is an SSRI and is the only nonhormonal therapy that is specifically approved for hot flashes in the United States.
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Does hormone replacement therapy help depression?

One study published in JAMA Psychiatry found that hormone therapy may help ward off symptoms of peri- and postmenopausal depression in some women.
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HRT vs Antidepressants in Perimenopausal Depression by Prof Jayashri Kulkarni



Does HRT make you feel happier?

Many women find that they feel calmer, have more energy, are more motivated and generally much happier when they take HRT. Some women also need to take the hormone testosterone which is usually given as a gel but can also be given as an implant.
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Can HRT worsen depression?

There is evidence that some women experience unpleasant mood symptoms (such as irritability, depressed mood and anxiety) while receiving hormone replacement therapy (HRT) while taking the progestin / progesterone component of the HRT.
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Can I take HRT and antidepressants together?

Should You Get HRT If You're Already on Antidepressants? A concern for someone entering menopause and looking at HRT to deal with other symptoms would be whether or not the HRT will adversely impact the antidepressants. The good news is that they don't negatively affect each other, and you can be on both.
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Can antidepressants make menopause worse?

Women going through the menopause are being wrongly prescribed antidepressants which are making their symptoms worse and destroying their confidence, experts have warned. New research has found over a third of women going to their GP with symptoms of the menopause are being offered antidepressants.
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Do antidepressants affect estrogen levels?

From data reviewed herein, it is evident that most antidepressants can influence testosterone and estrogen levels.
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Can lack of estrogen cause depression?

Depression: Estrogen is thought to increase serotonin, which is a chemical in the brain that boosts mood. Estrogen deficiency may cause a decline in serotonin that contributes to mood swings or depression.
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How long does HRT take to improve mood?

It may take a few weeks to feel the effects of treatment and there may be some side effects at first. A GP will usually recommend trying treatment for 3 months to see if it helps. If it does not, they may suggest changing your dose, or changing the type of HRT you're taking.
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What does HRT do to you mentally?

While gender affirming hormone therapy usually results in an improvement in mood, some people may experience mood swings or a worsening of anxiety, depression, or other mental health conditions as a result of the shifts associated with starting a second puberty.
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Can HRT make you feel worse at first?

Estrogen can give side effects of headache, breast tenderness and mild nausea. These tend to be common when you first start hormone replacement or increase the dose but often settle after a few weeks.
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Does HRT cause weight gain?

Many women believe that taking HRT will make them put on weight, but there's no evidence to support this claim. You may gain some weight during the menopause, but this often happens regardless of whether you take HRT. Exercising regularly and eating a healthy diet should help you to lose any unwanted weight.
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How do I know if I need HRT?

If you're younger than age 45, you need enough estrogen to provide protection against the long-term health effects of estrogen deficiency. If you have lasting menopausal symptoms that significantly impair your quality of life, your doctor may recommend longer term treatment.
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What is the best antidepressant for menopause UK?

Paroxetine is the SSRI that works best for flushes and sweats. Its prescribed at 10mg, half the dose usually used to treat depression. An increase to 20mg will have no extra benefit on flushes and sweats.
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Can antidepressants cause hormone imbalance?

SSRIs, SNRIs, and TCAs increase levels of hormones, especially serotonin. While serotonin is a good thing in moderation, too much of any hormone can cause issues. Other antidepressant medications like Olanzapine and Lithium Carbonate can also affect the hormones in your body.
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Can menopause cause extreme anxiety?

A: The fluctuation of estrogen and another key hormone, progesterone, in your body can cause feelings of anxiety or depression. But frequent, troubling high anxiety or panic attacks are not a normal part of menopause. Some women develop a panic disorder during menopause.
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Is HRT or antidepressants better for menopause?

Conclusions: The data suggest that antidepressant and antianxiety medications are more helpful than HRT in relieving peri- and postmenopausal depression or anxiety. However, most women managed the mood changes associated with menopause without psychopharmacologic intervention.
Takedown request   |   View complete answer on pubmed.ncbi.nlm.nih.gov


Why do you feel worse when starting antidepressants?

When you start an antidepressant medicine, you may feel worse before you feel better. This is because the side effects often happen before your symptoms improve. Remember: Over time, many of the side effects of the medicine go down and the benefits increase.
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What does low estrogen feel like?

Low estrogen can affect your body in various ways, depending on where you are in terms of your sexual development. Low estrogen: May delay puberty, slow or prevent sexual development. Occurs in perimenopause and menopause, often leading to painful sex, lower sexual desire and hot flashes.
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Does HRT make you look younger?

One of the benefits of hormone replacement therapy is that it can make you look younger. Hormone replacement therapy, or more specifically estrogen, can help reduce the appearance of fine lines and wrinkles on the skin. It can also promote hair growth, which can contribute to a more youthful appearance.
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What are the benefits of taking HRT?

Benefits of HRT include:
  • Reduction in vasomotor symptoms.
  • Improvement in quality of life. ...
  • Improvement in mood changes.
  • Improvement of urogenital symptoms.
  • Reduction in osteoporosis risk.
  • Reduction in cardiovascular disease.
  • Lower risk of colorectal cancer.
  • Other benefits.
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How does HRT change your face?

Coming back to the main question, of whether HRT changes your face, if you are undergoing HRT it is possible you may notice some facial changes. The main ones you may experience are increased skin thickness, elasticity, and hydration, along with the possibility of less wrinkles.
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