What is auto-PEEP?

Auto-positive end expiratory pressure (auto-PEEP) is a physiologic event that is common to mechanically ventilated patients. Auto-PEEP is commonly found in acute severe asthma, chronic obstructive pulmonary disease, or patients receiving inverse ratio ventilation.
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How do you treat auto PEEP?

Treating auto-PEEP
  1. Decreasing respiratory rate will increase the time between breaths and decrease the inspiratory to expiratory (I:E) ratio to 1:3 to 1:5.
  2. Increasing the inspiratory rate to 60 to 100 L/min will assure fast delivery of air during inspiration, lending more time for exhalation.
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Is Auto PEEP the same as breath stacking?

AutoPEEP may also be referred to as air-trapping, breath stacking, dynamic hyperinflation, inadvertent PEEP, or occult PEEP. AutoPEEP is a common phenomenon in mechanically ventilated patients with long expiratory time constants, for example patients with chronic obstructive pulmonary disease or acute severe asthma.
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How is auto PEEP determined?

Look at the inspiratory/expiratory flow waveform: If the waveform does not return to baseline (still expiring when delivery of breath initiates), there's probably auto PEEP!
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How do you adjust the auto PEEP on a ventilator?

When intrinsic PEEP is diagnosed, the patient should temporarily be released from mechanical ventilation to allow for full expiration. The ventilator can then be adjusted to shorten inspiration by decreasing the set tidal volume, increasing the inspiratory flow rate, or reducing the frequency of respirations.
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Morning Rounds: Understanding auto PEEP



What is normal PEEP on ventilator?

This, in normal conditions, is ~0.5, while in ARDS it can range between 0.2 and 0.8. This underlines the need for measuring the transpulmonary pressure for a safer application of mechanical ventilation.
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Which mode of ventilation is associated with auto PEEP?

Auto-PEEP occurs in patients receiving mechanical ventilation in the acute stage of acute respiratory failure when they have excessive minute ventilation, resulting in a relatively short expiratory time.
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Is PEEP good for COPD patients?

Mechanical ventilation with positive end-expiratory pressure (PEEP) is a widely used technique to improve pulmonary oxygenation in patients with the adult respiratory distress syndrome (ARDS) [1]. In contrast, the use of PEEP has generally been discouraged in patients with chronic obstructive pulmonary disease (COPD).
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How much PEEP is too much?

Increasing PEEP to 10 and higher resulted in significant declines in cardiac output. A PEEP of 15 and higher resulted in significant declines in oxygen delivery.
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What causes high PEEP alarm?

A high PEEP alarm occurs when the level of PEEP exceeds the preset PEEP. The most common cause is when auto-PEEP or air trapping occurs. Autopeep is when air pressure remains in the lungs at the end of exhalation, which increases the work of breathing.
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Does PEEP increase blood pressure?

Our study found that when PEEP was below 4 cm H2O in the both control and hypertension groups, blood pressure was unaffected by PEEP. However, when PEEP was above 4 cm H2O, the increase in PEEP led to decreased blood pressure and PEEP was negatively correlated with blood pressure in the hypertension group.
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Which mode of mechanical ventilation is at highest risk of developing auto PEEP?

Patients on volume-targeted modes, with an obstructive or reactive airways disease, receiving a high minute-ventilation, or on inverse ratio ventilation are at high risk for auto-PEEP.
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How do you prevent breath stacking on a ventilator?

Pressure-support ventilation and increased inspiratory time were independently associated with the reduction of asynchrony index. Conclusions: Compared with increasing sedation-analgesia, adapting the ventilator to patient breathing effort reduces breath-stacking asynchrony significantly and often dramatically.
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What is a high auto PEEP?

Auto-positive end expiratory pressure (auto-PEEP) is a physiologic event that is common to mechanically ventilated patients. Auto-PEEP is commonly found in acute severe asthma, chronic obstructive pulmonary disease, or patients receiving inverse ratio ventilation.
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What is the difference between PEEP and CPAP?

Positive end-expiratory pressure (PEEP) is the pressure in the alveoli above atmospheric pressure at the end of expiration. CPAP is a way of delivering PEEP but also maintains the set pressure throughout the respiratory cycle, during both inspiration and expiration.
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Can high PEEP cause pneumothorax?

High PEEP had been reported to be associated with pneumothorax[1] but several studies have found no such relationship[15,17,23,28,37]. Increased pressure is not enough by itself to produce alveolar rupture, with some studies demonstrating that pneumothorax is related to high tidal volume[37].
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What is the highest PEEP on ventilator?

PEEP of 29 appears to be the highest tolerated PEEP in our patient. We noted an initial rise in blood flow across all cardiac valves followed by a gradual decline. Studies are needed to investigate the immediate effect and long-term impact of PEEP on cardiopulmonary parameters and clinical outcomes.
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How does PEEP improve oxygenation?

So PEEP: Reduces trauma to the alveoli. Improves oxygenation by 'recruiting' otherwise closed alveoli, thereby increasing the surface area for gas exchange. Increases the functional residual capacity- the reserve in the patients lungs between breaths which will also help improve oxygenation.
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What does high PEEP mean on ventilator?

Background. Positive end-expiratory pressure (PEEP) is widely used to improve oxygenation and prevent alveolar collapse in mechanically ventilated patients with the acute respiratory distress syndrome (ARDS).
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Why is PEEP used?

The use of PEEP mainly has been reserved to recruit or stabilize lung units and improve oxygenation in patients who have hypoxemic respiratory failure. It has been shown that this helps the respiratory muscles to decrease the work of breathing and the amount of infiltrated-atelectatic tissues.
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What are the indications for PEEP?

INDICATIONS: PEEP is commonly used in patients who are suspected of having a pathology that predisposes their alveoli to collapse, this is generally due to a large amount of fluid in the lungs. As with CPAP; COPD, heart failure, and near drowning are common indications.
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What is ARDS protocol?

An ARDS protocol can serve as a guide to performing low tidal volume ventilation for mechanically ventilated patients: Start in any ventilator mode with initial tidal volumes of 8 mL/kg predicted body weight in kg, calculated by: [2.3 *(height in inches - 60) + 45.5 for women or + 50 for men].
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How does PEEP affect cardiac output?

Clinical Reasoning

Second, PEEP increases intrathoracic pressure, particularly when used in focal processes. This decreases venous return and cardiac output with subsequent adverse effects on systemic blood pressure and tissue oxygen delivery.
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Is a lower PEEP better?

Higher PEEP levels may improve oxygenation and reduce ventilator-induced lung injury but may also cause circulatory depression and lung injury from overdistention.
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What does a PEEP of 5 mean?

A higher level of applied PEEP (>5 cmH2O) is sometimes used to improve hypoxemia or reduce ventilator-associated lung injury in patients with acute lung injury, acute respiratory distress syndrome, or other types of hypoxemic respiratory failure.
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