What is an alternative to desmopressin?

Alternatives to desmopressin as pharmacologic therapy for DI include synthetic vasopressin and the nonhormonal agents chlorpropamide, carbamazepine, clofibrate (no longer on the US market), thiazides, and nonsteroidal anti-inflammatory drugs (NSAIDs).

What is the drug of choice for diabetes insipidus?

Central diabetes insipidus.

Typically, this form is treated with a synthetic hormone called desmopressin (DDAVP, Nocdurna). This medication replaces the missing anti-diuretic hormone (ADH) and decreases urination. You can take desmopressin in a tablet, as a nasal spray or by injection.

Can desmopressin be taken long term?

Desmopressin is the medicine commonly used to treat bedwetting. It can be used both short-term (eg, for a school trip or a sleepover) and long-term.

Who should not take desmopressin?

tell your doctor if you have or have ever had kidney disease or a low level of sodium in your blood. Your doctor will probably tell you not to take desmopressin. tell your doctor if you have or have ever had high blood pressure, any condition that causes you to be extremely thirsty, cystic fibrosis, or heart disease.

What is the generic drug for desmopressin?

Vasopressin, also known as anti-diuretic hormone, is a natural hormone that controls the amount of water in our body. Desmopressin (DDAVP) is the man-made version of vasopressin that works better to control urination and water balance in our bodies.

NCLEX Question Review - Desmopressin

How do I wean off desmopressin?

After a few months of being dry at a particular dose, you may want to wean off the medicine. If so, try taking one less tablet each night for two weeks until you have weaned to one tablet each night. Then try taking the medicine every other day for a month and then stop the DDAVP entirely.

Can desmopressin cause weight gain?

A: If you drink large volumes of fluids and take too much desmopressin, your body may become overloaded with fluid, which could result in headaches, dizziness and abnormal weight gain.

Does desmopressin hurt your kidneys?

The doctor may need to stop or adjust desmopressin treatment, especially in children and older adults. Children may be more sensitive to the side effects of this drug, especially water/mineral imbalance and a low level of sodium in the blood. Kidney function declines as you grow older.

What medicine can stop bed wetting?

The two drugs approved by the FDA specifically for bed-wetting are DDAVP and Tofranil. Other medications that are sometimes used to treat bed-wetting include Ditropan and Levsin. Drug therapy does not work for everyone, and these medications can have significant side effects.

What happens if you drink water after taking desmopressin?

Use the medicine exactly as directed. Limit your intake of water and other fluids while you are using desmopressin. Drinking too much water may lead to a serious, life-threatening electrolyte imbalance. Fluid restriction is especially important in children and older adults using desmopressin.

Does desmopressin cause memory loss?

The results confirm that memory impairment is a common side-effect of ECT and suggest that desmopressin may prevent ECT-induced memory impairment by its effects on memory and the learning process.

How safe is desmopressin?

Treatment with intranasal and oral formulations of desmopressin is generally well tolerated, and side effects are usually minor. The risk of hyponatraemia, although small, can be reduced by adhering to the indications, dosing recommendations and precautions when prescribing desmopressin.

How long before bed should you take desmopressin?

Desmopressin lasts eight hours so it must be taken just before your child goes to sleep and there must be no drinks until eight hours after it has been taken. It can be more effective to take Desmopressin an hour before going to sleep so that it's already working on slowing wee production as your child goes to bed.

Can diabetes insipidus go away?

There's no cure for diabetes insipidus. But treatments can relieve your thirst and decrease your urine output and prevent dehydration.

What should people with diabetes insipidus avoid?

If your condition is mild, your GP or endocrinologist may suggest reducing the amount of salt and protein in your diet, which will help your kidneys produce less urine. This may mean eating less salt and protein-rich food, such as processed foods, meat, eggs and nuts.

What happens if diabetes insipidus is left untreated?

Without treatment, diabetes insipidus can cause dehydration and, eventually, coma due to concentration of salts in the blood, particularly sodium.

How long can a child stay on desmopressin?

In practice most children need to Page 4 4 Copyright Bladder & Bowel UK (2019) take Desmopressin for 6 – 12 months (with a week-long break after every 12 weeks), but they can stay on it for years if necessary.

How can I stop bedwetting permanently?

Is there a pill to stop peeing at night?

The drug desmopressin (DDAVP) reduces urine production at night.

What are side effects of desmopressin?

What medications interact with desmopressin?

Can desmopressin cause high blood pressure?

Infrequently, desmopressin may affect your blood pressure. It may cause an increase or decrease in your blood pressure. A temporary drop in your blood pressure may result in dizziness and a fast heartbeat. Ask your doctor for more details, especially if you have heart problems or high or low blood pressure.

Can you drink alcohol on desmopressin?

Alcohol may reduce the effect of desmopressin. Avoid drinking alcohol while taking desmopressin.

Can desmopressin cause depression?

Adverse Effects of Desmopressin

Although extremely rare, fluid intoxication associated with desmopressin overdosage can lead to central nervous system disturbances, including depression, increased salivation, vomiting, ataxia, muscle tremors, coma, and convulsions.

Does desmopressin affect heart rate?

Desmopressin acutely decreases tachycardia and improves symptoms in the postural tachycardia syndrome. Heart Rhythm.