What is aggressive chemo?

Aggressive care includes chemotherapy after multiple earlier rounds of treatment have stopped working and being admitted to an intensive care unit. Such interventions at the end of life “are widely recognized to be harmful,” Chen said.
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What is an aggressive cancer treatment?

Aggressive, systemic treatment of metastatic cancer has evolved over time. For decades, it primarily involved chemotherapy, as well as hormone treatments for cancers like breast and prostate, but now includes a growing number of targeted therapies and immunotherapy.
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What does aggressive mean cancer?

Listen to pronunciation. (uh-GREH-siv) In medicine, describes a tumor or disease that forms, grows, or spreads quickly. It may also describe treatment that is more severe or intense than usual.
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Can aggressive cancer be cured?

While advanced cancers cannot be cured, there are still things that can be done to help you feel as good as possible for as long as possible. This care, aimed at relieving suffering and improving the quality of life, is called palliative care. Palliative care focuses on the patient and family rather than the disease.
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What is the most aggressive form of chemotherapy?

Doxorubicin (Adriamycin) is one of the most powerful chemotherapy drugs ever invented. It can kill cancer cells at every point in their life cycle, and it's used to treat a wide variety of cancers. Unfortunately, the drug can also damage heart cells, so a patient can't take it indefinitely.
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How does chemotherapy work? - Hyunsoo Joshua No



Which cancers are most aggressive?

The top five most aggressive cancers are:
  • Lung cancer.
  • Colorectal cancer.
  • Breast cancer.
  • Pancreatic cancer.
  • Prostate cancer.
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How many rounds of chemo can a person have?

During a course of treatment, you usually have around 4 to 8 cycles of treatment. A cycle is the time between one round of treatment until the start of the next. After each round of treatment you have a break, to allow your body to recover.
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What stage is aggressive cancer?

Cancer grades

grade 3 – cancer cells that look abnormal and may grow or spread more aggressively.
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Is aggressive cancer easier to treat?

Why is Rare and Aggressive Cancer Difficult to Treat? Rare and aggressive cancers often present tough challenges that make them more difficult to treat than common tumor types. For a rare cancer case, doctors may not have a standard FDA-approved therapy to help guide them in clinical decision-making.
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What makes cancer more aggressive?

Researchers have now discovered that some cancer cells can accumulate fat droplets, which appear to make them more aggressive and increase their ability to spread. It has been established that not all cancer cells are equally aggressive -- most can be neutralized with radiation and chemotherapy.
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Why does cancer come back more aggressive?

A cancer recurrence happens because, in spite of the best efforts to rid you of your cancer, some cells from your cancer remained. These cells can grow and may cause symptoms. These cells could be in the same place where your cancer first originated, or they could be in another part of your body.
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What are the symptoms of aggressive cancer?

Some common signs of metastatic cancer include:
  • pain and fractures, when cancer has spread to the bone.
  • headache, seizures, or dizziness, when cancer has spread to the brain.
  • shortness of breath, when cancer has spread to the lung.
  • jaundice or swelling in the belly, when cancer has spread to the liver.
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Can cancer spread while on chemo?

While chemotherapy is one of the oldest and most successful ways of treating cancer, it doesn't always work. So, yes, cancer can spread during chemotherapy. Spreading could mean the tumor keeps growing, or that the original tumor shrinks, but cancer metastasizes, forming tumors in other areas of the body.
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What is aggressive treatment?

Aggressive treatments were defined as intensive-care-unit stay, ventilator support, resuscitation, feeding tube, nonpalliative chemotherapy, and antibiotics. Outcome measures included the duration of hospice care received and various measures of quality of death.
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What is the life expectancy of someone with metastatic cancer?

A patient with widespread metastasis or with metastasis to the lymph nodes has a life expectancy of less than six weeks. A patient with metastasis to the brain has a more variable life expectancy (one to 16 months) depending on the number and location of lesions and the specifics of treatment.
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Does chemo work on aggressive cancer?

Since cancer cells multiply or divide quickly, chemo may be considered a first line of treatment for more aggressive forms of cancer.
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Which cancers spread the fastest?

Examples of fast-growing cancers include:
  • acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML)
  • certain breast cancers, such as inflammatory breast cancer (IBC) and triple-negative breast cancer (TNBC)
  • large B-cell lymphoma.
  • lung cancer.
  • rare prostate cancers such as small-cell carcinomas or lymphomas.
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Why do oncologists push chemo?

An oncologist may recommend chemotherapy before and/or after another treatment. For example, in a patient with breast cancer, chemotherapy may be used before surgery, to try to shrink the tumor. The same patient may benefit from chemotherapy after surgery to try to destroy remaining cancer cells.
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What are the signs that chemo is working?

Complete response - all of the cancer or tumor disappears; there is no evidence of disease. A tumor marker (if applicable) may fall within the normal range. Partial response - the cancer has shrunk by a percentage but disease remains. A tumor marker (if applicable) may have fallen but evidence of disease remains.
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How do you know if chemo is killing you?

Here are some signs that chemotherapy may not be working as well as expected: tumors aren't shrinking. new tumors keep forming. cancer is spreading to new areas.
...
Along the way, the timeline may have to be adjusted due to:
  1. low blood counts.
  2. adverse effects to major organs.
  3. severe side effects.
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What is the life expectancy after chemotherapy?

During the 3 decades, the proportion of survivors treated with chemotherapy alone increased from 18% in 1970-1979 to 54% in 1990-1999, and the life expectancy gap in this chemotherapy-alone group decreased from 11.0 years (95% UI, 9.0-13.1 years) to 6.0 years (95% UI, 4.5-7.6 years).
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How long can chemo prolong life?

For most cancers where palliative chemotherapy is used, this number ranges from 3-12 months. The longer the response, the longer you can expect to live.
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Does each chemo session get worse?

The effects of chemo are cumulative. They get worse with each cycle. My doctors warned me: Each infusion will get harder. Each cycle, expect to feel weaker.
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