What is a second line drug?

Any therapeutic agent that is not the drug of choice, or the 1^st normally used to treat a particular condition; in rheumatoid arthritis, 2^nd-line agents are used when standard 'first-line' therapy–ie, anti-inflammatory agents and corticosteroids fail.

What is first-line and second line drugs?

The first-line therapeutic drugs are the most effective and least toxic for use in the treatment of TB, while the second-line therapeutic drugs are less effective, more expensive and have higher toxicities. They are however, essential for the treatment of drug resistant forms of the bacteria (MDR-TB).

What is a first-line drug?

a drug that is the first choice for treating a particular condition because it is considered a very effective treatment for that condition with the least likelihood of causing side effects. A first-line medication may be a class of drugs (e.g., SSRIs for depression) as well as a single drug.

What is third line treatment?

Treatment that is given when both initial treatment (first-line therapy) and subsequent treatment (second-line therapy) don't work, or stop working.

What are third line drugs?

Third line therapy is usually defined as a regimen for an individual who has developed resistance to at least one drug in all three classes of anti-HIV therapies [nucleoside analogue reverse transcriptase inhibitors (NRTIs), non-nucleoside reverse transcriptase inhibitors (NNRTIs) and protease inhibitors] or has failed ...

ANTITUBERCULAR DRUGS (ATT) | Tricks And Mnemonics To Remember First Line And Second Line Drugs |

How do you know if chemo is killing you?

What are the third line drugs for TB?

What are the 4 TB drugs?

What is first line treatment for TB?

Of the approved drugs, isoniazid (INH), rifampin (RIF), ethambutol (EMB), and pyrazinamide (PZA) are considered first-line anti-TB drugs and form the core of standard treatment regimens (Figure 6.4) (Table 6.2).

What is front line treatment?

The first treatment given for a disease. It is often part of a standard set of treatments, such as surgery followed by chemotherapy and radiation.

What is the first line drug for high blood pressure?

There are three main classes of medication that are usually in the first line of treatment for hypertension: 1. Calcium Channel Blockers (CCB) 2. Angiotensin Converting Enzyme inhibitors (ACE inhibitors or ACE-I) and Angiotensin Receptor Blockers (ARBs) 3. Diuretics.

Why are beta-blockers not first line for hypertension?

In summary, beta-blockers are effective in preventing cardiovascular disease but are no longer suitable for routine initial treatment of hypertension because their cardiovascular protection and metabolic effects are worse than those of other antihypertensive drugs.

What is a second line antibiotic?

The most commonly used second-line therapies include amoxicillin/clavulanate, second- or third-generation cephalosporins (eg, cefuroxime, cefpodoxime, cefdinir), macrolides (ie, clarithromycin), fluoroquinolones (eg, ciprofloxacin, levofloxacin, moxifloxacin), and clindamycin.

What is the second line treatment for asthma?

Among the 3 second-line treatments, double-dose ICS plus LABA was the most efficient to take the complete control of asthma for stepping up treatments, while having the risk of peumonia or lung infections.

When is TB second line used?

The second line drugs include levofloxacin, moxifloxacin, bedaquiline, delamanid and linezolid. There is also pretomanid which is a new second line drug recommended in 2019 for the treatment of drug resistant TB. All the second line drugs should only be used under the supervision of an experienced doctor.

What are the 3 types of tuberculosis?

How many different lines of antibiotics against TB are there?

There are four first-line drugs against tuberculosis (isoniazid – INH, rifampicin – RMP, ethambutol – EMB, pyrazinamide – PZA) and nearly 20s-line drugs, which can be administered during the treatment of drug-resistant tuberculosis.

What is the most commonly used drug to treat TB?

The most common treatment for active TB is isoniazid INH in combination with three other drugs—rifampin, pyrazinamide and ethambutol. You may begin to feel better only a few weeks after starting to take the drugs but treating TB takes much longer than other bacterial infections.

What are the two phases in TB?

The standard six month course of treatment consists of two phases. The first phase lasts two months and is called the intensive phase. The second phase lasts four months and is called the continuous phase.

Which is harder on the body chemo or radiation?

Since radiation therapy is focused on one area of your body, you may experience fewer side effects than with chemotherapy. However, it may still affect healthy cells in your body.

What should you not do during chemotherapy?

Does chemo shorten your life?

During the 3 decades, the proportion of survivors treated with chemotherapy alone increased from 18% in 1970-1979 to 54% in 1990-1999, and the life expectancy gap in this chemotherapy-alone group decreased from 11.0 years (95% UI, 9.0-13.1 years) to 6.0 years (95% UI, 4.5-7.6 years).

What is the full form of dots?

The full form of DOTS is the Directly Observed Therapy, Short-course. It is also known as TB – DOTS. It refers to a strategy aimed at curing and reducing the risk of TB (tuberculosis) cases.